SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ME6_D_CGED501_1 (CYTOCHROME P450 2B4)	2bdr	UREIDOGLYCOLATE HYDROLASE (Pseudomonas putida)	5 / 9	PHE A 110 ILE A 93 ALA A 15 VAL A 124 VAL A 95	None	1.23A	3me6D-2bdrA: undetectable	3me6D-2bdrA: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7B_B_HAEB1270_1 (COLLAGENASE 3)	2bdr	UREIDOGLYCOLATE HYDROLASE (Pseudomonas putida)	4 / 5	HIS A 127 HIS A 76 GLU A 74 HIS A 126	None NA A 402 (-3.7A) NA A 402 (-3.3A) NA A 402 (-4.0A)	1.39A	4a7bB-2bdrA: undetectable	4a7bB-2bdrA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A99_D_MIYD392_1 (TETX2 PROTEIN)	2bdr	UREIDOGLYCOLATE HYDROLASE (Pseudomonas putida)	4 / 5	HIS A 153 GLN A 159 SER A 104 VAL A 107	None	1.46A	4a99D-2bdrA: undetectable	4a99D-2bdrA: 16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBZ_C_DAHC123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	2bdr	UREIDOGLYCOLATE HYDROLASE (Pseudomonas putida)	5 / 11	PHE A 14 THR A 10 SER A 112 ILE A 93 PHE A 110	None	1.00A	6ebzC-2bdrA: undetectable	6ebzC-2bdrA: 16.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ME6_D_CGED501_1","CYTOCHROME P450 2B4","2bdr","UREIDOGLYCOLATE HYDROLASE","Pseudomonas putida",5,"PHE A 110;ILE A  93;ALA A  15;VAL A 124;VAL A  95","None","1.23A","3me6D-2bdrA:undetectable","3me6D-2bdrA:16.81"],["4A7B_B_HAEB1270_1","COLLAGENASE 3","2bdr","UREIDOGLYCOLATE HYDROLASE","Pseudomonas putida",4,"HIS A 127;HIS A  76;GLU A  74;HIS A 126","None; NA A 402 (-3.7A); NA A 402 (-3.3A); NA A 402 (-4.0A)","1.39A","4a7bB-2bdrA:undetectable","4a7bB-2bdrA:20.60"],["4A99_D_MIYD392_1","TETX2 PROTEIN","2bdr","UREIDOGLYCOLATE HYDROLASE","Pseudomonas putida",4,"HIS A 153;GLN A 159;SER A 104;VAL A 107","None","1.46A","4a99D-2bdrA:undetectable","4a99D-2bdrA:16.83"],["6EBZ_C_DAHC123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","2bdr","UREIDOGLYCOLATE HYDROLASE","Pseudomonas putida",5,"PHE A  14;THR A  10;SER A 112;ILE A  93;PHE A 110","None","1.00A","6ebzC-2bdrA:undetectable","6ebzC-2bdrA:16.00"]]