SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bdt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 2bdt BH3686
(Bacillus
halodurans) 		6 / 12 THR A  18
ILE A 107
GLY A   9
ILE A   7
VAL A 136
GLU A 140
 None
 1.08A 1sg9B-2bdtA:
undetectable		 1sg9B-2bdtA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 2bdt BH3686
(Bacillus
halodurans) 		6 / 12 THR A  18
ILE A 107
GLY A   9
ILE A   7
VAL A 136
GLU A 140
 None
 1.19A 1vq1B-2bdtA:
undetectable		 1vq1B-2bdtA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 2bdt BH3686
(Bacillus
halodurans) 		5 / 12 LEU A 115
GLU A 138
VAL A 136
PRO A  10
GLY A  34
 None
 1.14A 4q15A-2bdtA:
2.2		 4q15A-2bdtA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 2bdt BH3686
(Bacillus
halodurans) 		5 / 12 LEU A 115
GLU A 138
VAL A 136
PRO A  10
GLY A  34
 None
 1.11A 4q15B-2bdtA:
2.3		 4q15B-2bdtA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 2bdt BH3686
(Bacillus
halodurans) 		5 / 12 LEU A 115
GLU A 138
VAL A 136
PRO A  10
GLY A  34
 None
 1.08A 4ydqA-2bdtA:
2.5		 4ydqA-2bdtA:
17.37