SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2be4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 7 ALA A 123
GLU A 125
LEU A 126
MET A 154
 None
 0.93A 1hk2A-2be4A:
2.4		 1hk2A-2be4A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 8 ALA A 203
GLY A 211
HIS A 270
PHE A 198
 None
 0.78A 1sv9A-2be4A:
undetectable		 1sv9A-2be4A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		5 / 12 LEU A 167
LEU A 266
ALA A 263
LEU A 245
MET A 107
 None
 1.30A 1ya3A-2be4A:
undetectable		 1ya3A-2be4A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 6 LEU A 182
LEU A 268
MET A 107
LEU A 167
 None
 1.01A 1z95A-2be4A:
undetectable		 1z95A-2be4A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 6 ARG A 194
ARG A 172
GLU A  87
GLU A  88
 None
 1.15A 3k9fA-2be4A:
undetectable
3k9fB-2be4A:
undetectable
3k9fD-2be4A:
undetectable		 3k9fA-2be4A:
20.16
3k9fB-2be4A:
20.16
3k9fD-2be4A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 6 LEU A  91
GLU A  88
PRO A  85
ARG A 172
 None
 1.40A 3ltwA-2be4A:
undetectable		 3ltwA-2be4A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 7 LEU A 182
LEU A 268
MET A 107
LEU A 167
 None
 1.03A 4okwA-2be4A:
undetectable		 4okwA-2be4A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 7 ARG A 242
VAL A 222
LEU A 245
GLU A 243
 None
 1.10A 4zphA-2be4A:
undetectable
4zphB-2be4A:
undetectable		 4zphA-2be4A:
20.31
4zphB-2be4A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		5 / 12 ILE A  83
ALA A  80
ILE A  16
LEU A  84
LEU A  33
 None
 1.14A 6a5zD-2be4A:
undetectable		 6a5zD-2be4A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 6 GLY A 119
LEU A 167
PHE A 198
PHE A 202
 None
 1.04A 6h7lA-2be4A:
undetectable		 6h7lA-2be4A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 6 GLY A 119
LEU A 167
PHE A 198
PHE A 202
 None
 1.03A 6h7lB-2be4A:
0.0		 6h7lB-2be4A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 6 ASP A 162
TYR A 120
ASP A 169
GLU A  87
 None
 1.47A 6mn5A-2be4A:
undetectable		 6mn5A-2be4A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2be4 HYPOTHETICAL PROTEIN
LOC449832
(Danio
rerio) 		4 / 6 ASP A 162
TYR A 120
ASP A 169
GLU A  87
 None
 1.34A 6mn5C-2be4A:
undetectable		 6mn5C-2be4A:
17.27