SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2be7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 136
THR A 138
PRO A 135
 None
 0.76A 1dscC-2be7A:
undetectable		 1dscC-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		5 / 9 GLY A 127
HIS A 134
THR A 136
ILE A 125
SER A  59
 None
 1.11A 1gtnL-2be7A:
undetectable
1gtnM-2be7A:
undetectable		 1gtnL-2be7A:
13.19
1gtnM-2be7A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		5 / 10 GLY A 127
HIS A 134
THR A 136
ILE A 125
SER A  59
 None
 1.15A 1gtnU-2be7A:
undetectable
1gtnV-2be7A:
undetectable		 1gtnU-2be7A:
13.19
1gtnV-2be7A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 ARG A 269
THR A 280
VAL A 277
 None
 0.92A 1hxbA-2be7A:
undetectable		 1hxbA-2be7A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 136
THR A 138
PRO A 135
 None
 0.84A 1mnvD-2be7A:
undetectable		 1mnvD-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 136
THR A 138
PRO A 135
 None
 0.85A 1unjL-2be7A:
undetectable		 1unjL-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 136
THR A 138
PRO A 135
 None
 0.85A 1unjW-2be7A:
undetectable		 1unjW-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 138
PRO A 135
THR A 136
 None
 0.86A 1unjX-2be7A:
undetectable		 1unjX-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 136
THR A 138
PRO A 135
 None
 0.85A 1unjX-2be7A:
undetectable		 1unjX-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 136
THR A 138
PRO A 135
 None
 0.84A 1unmE-2be7A:
undetectable		 1unmE-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 138
PRO A 135
THR A 136
 None
 0.87A 1unmF-2be7A:
undetectable		 1unmF-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 THR A 136
THR A 138
PRO A 135
 None
 0.81A 1unmF-2be7A:
undetectable		 1unmF-2be7A:
3.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		5 / 10 GLY A 127
HIS A 134
THR A 136
ILE A 125
SER A  59
 None
 1.16A 1utdQ-2be7A:
undetectable
1utdR-2be7A:
undetectable		 1utdQ-2be7A:
13.19
1utdR-2be7A:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		4 / 5 ARG A 106
PHE A  49
THR A  56
LEU A  58
 None
None
SO4  A 311 (-4.3A)
None
 1.49A 2e1qD-2be7A:
undetectable		 2e1qD-2be7A:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda) 		3 / 3 CYH D 108
CYH D 113
HIS D 116
 ZN  D1108 (-2.2A)
ZN  D1108 (-2.3A)
None
 0.74A 2iwkA-2be7D:
undetectable		 2iwkA-2be7D:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda) 		3 / 3 CYH D 108
CYH D 113
HIS D 116
 ZN  D1108 (-2.2A)
ZN  D1108 (-2.3A)
None
 0.75A 2iwkB-2be7D:
undetectable		 2iwkB-2be7D:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		3 / 3 ARG A 269
THR A 280
VAL A 277
 None
 0.86A 2qakA-2be7A:
undetectable		 2qakA-2be7A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		5 / 12 LEU A  21
LEU A 152
GLN A 133
LEU A 264
VAL A 224
 None
 1.20A 2qd4A-2be7A:
2.5		 2qd4A-2be7A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 5 ARG A 114
ASP A  15
ILE A  16
GLU D 141
 None
 1.13A 2xrzA-2be7A:
undetectable
2xrzB-2be7A:
undetectable		 2xrzA-2be7A:
24.21
2xrzB-2be7A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 7 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 1.18A 2zxwN-2be7D:
undetectable
2zxwW-2be7D:
undetectable		 2zxwN-2be7D:
17.43
2zxwW-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 7 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.98A 3ag2N-2be7D:
undetectable
3ag2W-2be7D:
undetectable		 3ag2N-2be7D:
17.43
3ag2W-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda) 		3 / 3 CYH D 108
CYH D 113
HIS D 116
 ZN  D1108 (-2.2A)
ZN  D1108 (-2.3A)
None
 0.84A 3dtuB-2be7D:
undetectable		 3dtuB-2be7D:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda) 		3 / 3 CYH D 108
CYH D 113
HIS D 116
 ZN  D1108 (-2.2A)
ZN  D1108 (-2.3A)
None
 0.83A 3dtuD-2be7D:
undetectable		 3dtuD-2be7D:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 6 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.88A 3wg7A-2be7D:
undetectable
3wg7J-2be7D:
undetectable		 3wg7A-2be7D:
17.43
3wg7J-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		4 / 8 ILE A  10
ILE A  24
ALA A 298
PRO A 135
 None
 0.78A 4jltA-2be7A:
undetectable		 4jltA-2be7A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda) 		3 / 3 CYH D 108
ASN D 112
LYS D 142
 ZN  D1108 (-2.2A)
None
None
 1.43A 4k50A-2be7D:
undetectable		 4k50A-2be7D:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda) 		5 / 11 ILE D  58
LYS D  27
ILE D  17
TYR D  15
THR D  35
 None
 1.48A 4p68A-2be7D:
undetectable		 4p68A-2be7D:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 7 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.78A 5b1aA-2be7D:
undetectable
5b1aJ-2be7D:
undetectable		 5b1aA-2be7D:
17.43
5b1aJ-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 7 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.98A 5b1bA-2be7D:
undetectable
5b1bJ-2be7D:
undetectable		 5b1bA-2be7D:
17.43
5b1bJ-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 7 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.84A 5b3sA-2be7D:
undetectable
5b3sJ-2be7D:
undetectable		 5b3sA-2be7D:
17.43
5b3sJ-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		5 / 11 ALA A 173
GLY A 166
THR A 228
ASP A 141
LEU A 140
 None
 1.12A 5lf7H-2be7A:
undetectable
5lf7I-2be7A:
undetectable		 5lf7H-2be7A:
23.67
5lf7I-2be7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		5 / 11 ALA A 173
GLY A 166
THR A 228
ASP A 141
LEU A 140
 None
 1.08A 5lf7V-2be7A:
undetectable
5lf7W-2be7A:
undetectable		 5lf7V-2be7A:
23.67
5lf7W-2be7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		5 / 12 ILE A 125
VAL A 303
LEU A 300
ILE A  64
PHE A  49
 None
 0.99A 5mueA-2be7A:
2.2		 5mueA-2be7A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		4 / 4 LEU A 225
LEU A 261
SER A 253
ALA A 257
 None
 1.01A 5uunA-2be7A:
undetectable		 5uunA-2be7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		4 / 7 ARG A 106
PHE A  50
LEU A  89
SER A  97
 None
 1.15A 5uxcA-2be7A:
undetectable		 5uxcA-2be7A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 8 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.80A 5zcoA-2be7D:
undetectable
5zcoJ-2be7D:
undetectable		 5zcoA-2be7D:
17.43
5zcoJ-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 7 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.81A 5zcpA-2be7D:
undetectable
5zcpJ-2be7D:
undetectable		 5zcpA-2be7D:
17.43
5zcpJ-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 7 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.83A 5zcqA-2be7D:
undetectable
5zcqJ-2be7D:
undetectable		 5zcqA-2be7D:
17.43
5zcqJ-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 8 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.89A 5zcqN-2be7D:
undetectable
5zcqW-2be7D:
undetectable		 5zcqN-2be7D:
17.43
5zcqW-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		4 / 7 SER A  59
HIS A 134
GLY A 127
LEU A 140
 None
 0.92A 6btxA-2be7A:
undetectable		 6btxA-2be7A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Moritella
profunda;
Moritella
profunda) 		4 / 6 ILE D 114
LEU A 115
ARG A 106
MET A 105
 None
 0.91A 6nmfN-2be7D:
undetectable
6nmfW-2be7D:
undetectable		 6nmfN-2be7D:
17.43
6nmfW-2be7D:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN
(Moritella
profunda) 		4 / 6 GLN A 288
PHE A 143
LEU A 152
PHE A 179
 None
 1.28A 6nmpC-2be7A:
undetectable
6nmpJ-2be7A:
undetectable		 6nmpC-2be7A:
21.89
6nmpJ-2be7A:
13.44