SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2be9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 2be9 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Sulfolobus
acidocaldarius) 		4 / 8 LEU B  36
ILE B  21
ILE B  70
ILE B  87
 None
 0.81A 2bu8A-2be9B:
undetectable		 2bu8A-2be9B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2be9 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Sulfolobus
acidocaldarius) 		4 / 5 ILE B  38
PHE B  44
ASP B  67
GLU B  66
 None
 1.15A 3kp6A-2be9B:
0.0
3kp6B-2be9B:
undetectable		 3kp6A-2be9B:
25.29
3kp6B-2be9B:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 2be9 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Sulfolobus
acidocaldarius) 		5 / 12 LEU B  36
ILE B  46
ILE B  78
ALA B  85
VAL B  12
 None
 1.25A 3vw1D-2be9B:
undetectable		 3vw1D-2be9B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 2be9 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Sulfolobus
acidocaldarius) 		3 / 3 PRO B 128
ILE B  78
SER B 121
 None
 0.70A 5fsaA-2be9B:
undetectable		 5fsaA-2be9B:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2be9 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Sulfolobus
acidocaldarius) 		5 / 12 ILE B  87
VAL B  95
ILE B  24
ALA B  85
VAL B  63
 None
 1.00A 5n0tA-2be9B:
undetectable		 5n0tA-2be9B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2be9 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN
(Sulfolobus
acidocaldarius) 		5 / 8 VAL B 107
ILE B 154
LEU B 111
ILE B 158
ILE B  81
 None
 1.06A 5numA-2be9B:
undetectable		 5numA-2be9B:
20.24