SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2beo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLY A  44
VAL A  87
SER A  89
THR A  46
 None
 0.79A 3tj7A-2beoA:
undetectable
3tj7B-2beoA:
undetectable		 3tj7A-2beoA:
22.44
3tj7B-2beoA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLY A  44
VAL A  87
SER A  89
THR A  46
 None
 0.78A 3tj7C-2beoA:
undetectable
3tj7D-2beoA:
undetectable		 3tj7C-2beoA:
22.44
3tj7D-2beoA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		4 / 6 VAL A  87
SER A  89
THR A  46
GLY A  44
 None
 0.77A 3tj7C-2beoA:
undetectable
3tj7D-2beoA:
undetectable		 3tj7C-2beoA:
22.44
3tj7D-2beoA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		3 / 3 THR A  49
ASN A  59
GLU A  86
 None
 0.80A 3v4tA-2beoA:
undetectable
3v4tC-2beoA:
undetectable		 3v4tA-2beoA:
21.00
3v4tC-2beoA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		5 / 11 GLY A 138
ASP A 133
ALA A 218
GLY A 141
CYH A 144
 None
 1.43A 4c5lA-2beoA:
undetectable		 4c5lA-2beoA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		5 / 9 GLY A 138
ASP A 133
ALA A 218
GLY A 141
CYH A 144
 None
 1.44A 4c5lB-2beoA:
undetectable		 4c5lB-2beoA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		5 / 10 GLY A 138
ASP A 133
ALA A 218
GLY A 141
CYH A 144
 None
 1.44A 4c5lD-2beoA:
undetectable		 4c5lD-2beoA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		5 / 10 GLY A 138
ASP A 133
ALA A 218
GLY A 141
CYH A 144
 None
 1.44A 4c5nD-2beoA:
undetectable		 4c5nD-2beoA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		4 / 7 ALA A  92
THR A  93
ALA A  94
THR A  46
 None
 1.02A 4qw0K-2beoA:
undetectable		 4qw0K-2beoA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 2beo LISTERIOLYSIN
REGULATORY PROTEIN
(Listeria
monocytogenes) 		4 / 7 ALA A  92
THR A  93
ALA A  94
THR A  46
 None
 1.02A 4qw0Y-2beoA:
undetectable		 4qw0Y-2beoA:
21.80