SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bep'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 2bep UBIQUITIN-CONJUGATIN
G ENZYME E2-25 KDA
(Bos
taurus) 		4 / 8 LEU A 106
GLU A  15
ILE A   9
TYR A  66
 None
 0.97A 1qvtA-2bepA:
undetectable		 1qvtA-2bepA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 2bep UBIQUITIN-CONJUGATIN
G ENZYME E2-25 KDA
(Bos
taurus) 		5 / 11 ALA A 145
ILE A  79
ALA A 153
PRO A  50
PHE A 141
 None
 1.26A 2admA-2bepA:
undetectable		 2admA-2bepA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 2bep UBIQUITIN-CONJUGATIN
G ENZYME E2-25 KDA
(Bos
taurus) 		5 / 12 VAL A  16
LEU A 106
VAL A 109
THR A  77
VAL A  73
 None
 0.78A 2cbrA-2bepA:
undetectable		 2cbrA-2bepA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2bep UBIQUITIN-CONJUGATIN
G ENZYME E2-25 KDA
(Bos
taurus) 		5 / 8 SER A  85
TYR A  51
ARG A  74
ILE A  91
PHE A  75
 None
 1.49A 3ln1A-2bepA:
undetectable		 3ln1A-2bepA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 2bep UBIQUITIN-CONJUGATIN
G ENZYME E2-25 KDA
(Bos
taurus) 		4 / 5 LEU A  58
LEU A  96
PHE A  75
LEU A 116
 None
 1.04A 5gtrA-2bepA:
undetectable		 5gtrA-2bepA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2bep UBIQUITIN-CONJUGATIN
G ENZYME E2-25 KDA
(Bos
taurus) 		3 / 3 ILE A  91
VAL A  73
PRO A  71
 None
 0.67A 5uunA-2bepA:
undetectable		 5uunA-2bepA:
18.31