SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bfu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 6 TRP L 196
THR L 251
LEU L 344
GLY L 198
 None
 1.33A 1gtiC-2bfuL:
undetectable		 1gtiC-2bfuL:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_A_SAMA500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 10 SER L 237
TRP L 308
GLY L 356
PHE L 354
LEU L 193
 None
 1.39A 2c2bA-2bfuL:
0.0
2c2bB-2bfuL:
0.0		 2c2bA-2bfuL:
21.58
2c2bB-2bfuL:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_B_SAMB500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 10 LEU L 193
SER L 237
TRP L 308
GLY L 356
PHE L 354
 None
 1.37A 2c2bA-2bfuL:
0.0
2c2bB-2bfuL:
0.0		 2c2bA-2bfuL:
21.58
2c2bB-2bfuL:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_C_SAMC500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 10 SER L 237
TRP L 308
GLY L 356
PHE L 354
LEU L 193
 None
 1.43A 2c2bC-2bfuL:
0.0
2c2bD-2bfuL:
0.0		 2c2bC-2bfuL:
21.58
2c2bD-2bfuL:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_E_SAME500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 11 SER L 237
TRP L 308
GLY L 356
PHE L 354
LEU L 193
 None
 1.38A 2c2bE-2bfuL:
0.0
2c2bF-2bfuL:
undetectable		 2c2bE-2bfuL:
21.58
2c2bF-2bfuL:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_F_SAMF500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 10 LEU L 193
SER L 237
TRP L 308
GLY L 356
PHE L 354
 None
 1.39A 2c2bE-2bfuL:
0.0
2c2bF-2bfuL:
0.0		 2c2bE-2bfuL:
21.58
2c2bF-2bfuL:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 6 TYR L 278
GLY L 269
ASP L 321
ASN L 270
 None
 1.27A 2g72A-2bfuL:
undetectable		 2g72A-2bfuL:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 5 ILE L  68
PHE L  25
PHE L  62
ILE L  72
 None
 0.95A 2hjhA-2bfuL:
undetectable		 2hjhA-2bfuL:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus;
Cowpea
mosaic
virus) 		4 / 5 ILE S  56
PRO S  54
VAL L 146
PHE S 180
 None
 1.28A 2ygnA-2bfuS:
undetectable		 2ygnA-2bfuS:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 9 ILE L  68
ILE L 172
PHE L  25
PHE L 127
VAL L 150
 None
 1.16A 2ygpA-2bfuL:
0.0		 2ygpA-2bfuL:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		3 / 3 MET S  15
CYH S 148
PRO S  41
 None
 0.91A 3h52C-2bfuS:
undetectable		 3h52C-2bfuS:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 12 ILE S  39
GLY S  37
ALA S 134
ILE S  35
PRO S 179
 None
 0.84A 3jayA-2bfuS:
undetectable		 3jayA-2bfuS:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 12 ILE S  39
GLY S  37
ALA S 134
ILE S  35
PRO S 179
 None
 0.97A 3jb1A-2bfuS:
undetectable		 3jb1A-2bfuS:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6B_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 5 TRP L 239
PHE L 354
TRP L 235
PRO L 192
 None
 1.17A 3n6bA-2bfuL:
0.0
3n6bB-2bfuL:
0.0		 3n6bA-2bfuL:
20.95
3n6bB-2bfuL:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6D_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 6 TRP L 239
PHE L 354
TRP L 235
PRO L 192
 None
 1.07A 3n6dA-2bfuL:
undetectable
3n6dB-2bfuL:
0.0		 3n6dA-2bfuL:
20.95
3n6dB-2bfuL:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 11 ARG S 170
GLY S 173
SER L  94
GLY L 133
MET L 140
 None
 1.30A 4a6nC-2bfuS:
undetectable		 4a6nC-2bfuS:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 5 LEU S 146
ILE S  70
MET S 163
PHE S 122
 None
 1.05A 4dc3B-2bfuS:
undetectable		 4dc3B-2bfuS:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		3 / 3 GLN L 204
THR L 335
THR L 334
 None
 0.78A 4fu9A-2bfuL:
undetectable		 4fu9A-2bfuL:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		3 / 3 GLN L 204
THR L 335
THR L 334
 None
 0.76A 4fufA-2bfuL:
undetectable		 4fufA-2bfuL:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 7 MET L 238
ARG S 164
VAL S  59
PHE S 169
 None
 1.40A 4jseA-2bfuL:
undetectable
4jseB-2bfuL:
undetectable		 4jseA-2bfuL:
21.60
4jseB-2bfuL:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 8 THR S  19
ILE S  16
LEU S  74
ILE S 110
 None
 0.87A 4r38D-2bfuS:
1.3		 4r38D-2bfuS:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_1
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 6 ASN S 119
LEU S 118
GLU S 160
TYR S  11
 None
 1.28A 4wcxC-2bfuS:
undetectable		 4wcxC-2bfuS:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 7 VAL L 104
TRP L 115
LEU L  32
LEU L  42
 None
 0.94A 4xo7A-2bfuL:
undetectable		 4xo7A-2bfuL:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		5 / 12 GLY L 219
ILE L 236
LEU L 193
ILE L 217
GLY L 362
 None
 1.04A 5d4uC-2bfuL:
undetectable		 5d4uC-2bfuL:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2bfu COWPEA MOSAIC VIRUS,
LARGE (L) SUBUNIT
(Cowpea
mosaic
virus) 		4 / 7 ALA L 229
GLY L 220
SER L 366
GLY L 222
 None
 0.88A 5e26A-2bfuL:
undetectable
5e26B-2bfuL:
undetectable		 5e26A-2bfuL:
21.03
5e26B-2bfuL:
21.03