SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		3 / 3 ALA C 438
VAL C 443
TRP C 446
 None
 0.90A 1c4dA-2bg9C:
undetectable
1c4dB-2bg9C:
undetectable		 1c4dA-2bg9C:
3.01
1c4dB-2bg9C:
3.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.15A 1dz4A-2bg9A:
undetectable		 1dz4A-2bg9A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.15A 1dz4B-2bg9A:
undetectable		 1dz4B-2bg9A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 5 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.18A 1dz6A-2bg9A:
undetectable		 1dz6A-2bg9A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 8 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.11A 1dz9A-2bg9A:
undetectable		 1dz9A-2bg9A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 12 ILE A 102
PHE A 100
LEU A  92
LEU A  35
TYR A 203
 None
 1.47A 1fm6X-2bg9A:
undetectable		 1fm6X-2bg9A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 8 PHE A 225
SER A 287
PHE A 414
ILE A 420
 None
 1.17A 1gm7A-2bg9A:
undetectable
1gm7B-2bg9A:
undetectable		 1gm7A-2bg9A:
20.00
1gm7B-2bg9A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		5 / 12 LEU E  36
THR E  37
LEU E  49
ILE E 185
GLY E 181
 None
 1.01A 1qknA-2bg9E:
undetectable		 1qknA-2bg9E:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_A_ADNA1501_1
(CLASS B ACID
PHOSPHATASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 10 ASP A 195
THR A 154
GLY A 153
THR A 191
TYR A 190
 None
 1.27A 1rmtA-2bg9A:
undetectable		 1rmtA-2bg9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 5 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.13A 1t88B-2bg9A:
undetectable		 1t88B-2bg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 12 LEU A 410
LEU A 253
VAL A 232
PHE A 233
ILE A 417
 None
 1.32A 1uobA-2bg9A:
undetectable		 1uobA-2bg9A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
(Torpedo
marmorata) 		5 / 12 THR B 445
ILE B 296
VAL B 300
TYR B 441
ILE B 442
 None
 1.16A 1z9hD-2bg9B:
2.4		 1z9hD-2bg9B:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata) 		3 / 3 SER A 302
THR A 244
GLN E 249
 None
 0.82A 2fk8A-2bg9A:
undetectable		 2fk8A-2bg9A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 5 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.14A 2m56A-2bg9A:
undetectable		 2m56A-2bg9A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		3 / 3 ARG E 216
ASN E 224
THR E 275
 None
 0.75A 2q63A-2bg9E:
undetectable		 2q63A-2bg9E:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		5 / 12 ILE E 453
GLY E 461
ALA E 454
LEU E 455
PHE E 466
 None
 1.04A 2yvlA-2bg9E:
undetectable		 2yvlA-2bg9E:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.15A 2zawA-2bg9A:
undetectable		 2zawA-2bg9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		5 / 11 ILE E  55
LEU E  34
ILE E 208
VAL E  30
PRO E  87
 None
 1.24A 3a51A-2bg9E:
2.6		 3a51A-2bg9E:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		5 / 12 ILE E  55
LEU E  34
ILE E 208
VAL E  30
PRO E  87
 None
 1.22A 3a51D-2bg9E:
2.6		 3a51D-2bg9E:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 11 LEU A 253
PHE A 225
ILE A 289
PRO A 236
VAL A 295
 None
 1.29A 3aqiA-2bg9A:
undetectable		 3aqiA-2bg9A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 12 LEU A 253
PHE A 225
ILE A 289
PRO A 236
VAL A 295
 None
 1.32A 3aqiB-2bg9A:
undetectable		 3aqiB-2bg9A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
(Torpedo
marmorata) 		5 / 12 GLU B  45
SER B 126
ASN B  44
LEU B  43
ARG B 215
 None
 1.34A 3eigA-2bg9B:
undetectable		 3eigA-2bg9B:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 12 VAL A 215
PHE A 280
LEU A 433
ILE A 431
GLN A 435
 None
 1.37A 3elzC-2bg9A:
undetectable		 3elzC-2bg9A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.12A 3fwgA-2bg9A:
undetectable		 3fwgA-2bg9A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		5 / 11 MET C 257
LEU C 264
LEU B 237
GLY B 246
HIS C 320
 None
 1.31A 3hm1B-2bg9C:
undetectable		 3hm1B-2bg9C:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		5 / 10 SER C 258
LEU A 251
ILE A 247
SER B 250
SER B 254
 None
 1.44A 3ik6B-2bg9C:
undetectable
3ik6E-2bg9C:
undetectable		 3ik6B-2bg9C:
21.14
3ik6E-2bg9C:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 7 ASP E 202
ASP E 204
GLN E 206
GLN E 197
 None
 1.20A 3l2vA-2bg9E:
undetectable		 3l2vA-2bg9E:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata;
Torpedo
marmorata) 		4 / 8 SER C 258
ILE A 247
SER B 250
SER B 254
 None
 0.92A 3lslA-2bg9C:
undetectable
3lslD-2bg9C:
undetectable		 3lslA-2bg9C:
21.53
3lslD-2bg9C:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata) 		3 / 3 TYR E 104
ASP A  99
ASP A  97
 None
 0.78A 3ou6B-2bg9E:
undetectable		 3ou6B-2bg9E:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		3 / 3 TYR C 202
ASP C 214
ASP C 161
 None
 0.71A 3ou7B-2bg9C:
undetectable		 3ou7B-2bg9C:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 12 LEU A 253
PHE A 225
ILE A 289
PRO A 236
VAL A 295
 None
 1.37A 3w1wA-2bg9A:
undetectable		 3w1wA-2bg9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.11A 3wrhE-2bg9A:
undetectable		 3wrhE-2bg9A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.14A 3wrjE-2bg9A:
undetectable		 3wrjE-2bg9A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		5 / 9 ILE C  79
ASP C  64
LEU C  67
GLY C 116
ASN C 115
 None
 1.33A 4eb4C-2bg9C:
undetectable		 4eb4C-2bg9C:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 6 ILE E 225
ASN E 224
GLU E 182
VAL E 279
 None
 0.83A 4ejwB-2bg9E:
undetectable		 4ejwB-2bg9E:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.14A 4g3rA-2bg9A:
undetectable		 4g3rA-2bg9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 7 ILE E 209
ASP E 173
LEU E 212
PHE E 211
 None
 0.92A 4iqqA-2bg9E:
undetectable		 4iqqA-2bg9E:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 6 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.16A 4kkyX-2bg9A:
undetectable		 4kkyX-2bg9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
(Torpedo
marmorata) 		4 / 7 LEU B 158
PRO B  21
SER B  22
VAL B 116
 None
 1.24A 4klrA-2bg9B:
undetectable		 4klrA-2bg9B:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 5 LEU A  80
PRO A  81
LEU A 108
ILE A 116
 None
 1.04A 4klrA-2bg9A:
undetectable		 4klrA-2bg9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 5 PHE A 205
TYR A 181
LEU A  35
VAL A  50
 None
 1.16A 4l49A-2bg9A:
undetectable		 4l49A-2bg9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		5 / 12 LEU E 457
LEU E 460
LEU E 463
ALA E 464
CYH E 229
 None
 1.07A 4ltwA-2bg9E:
undetectable		 4ltwA-2bg9E:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 7 LEU E  49
ASN E  94
LEU E  34
ILE E 208
 None
 1.05A 4okwA-2bg9E:
undetectable		 4okwA-2bg9E:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 6 THR E 468
ALA E 464
LEU E 460
SER E 459
 None
 0.97A 4pwjA-2bg9E:
undetectable		 4pwjA-2bg9E:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 7 THR E 468
ALA E 464
LEU E 460
SER E 459
 None
 0.91A 4pwjB-2bg9E:
undetectable		 4pwjB-2bg9E:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
(Torpedo
marmorata) 		4 / 8 GLU A 262
LEU A 253
VAL B 261
LEU B 264
 None
 0.86A 4r3aA-2bg9A:
undetectable		 4r3aA-2bg9A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
(Torpedo
marmorata) 		5 / 12 LEU B 259
LEU B 297
MET B 446
VAL B 238
ILE B 442
 None
 1.08A 4x1yB-2bg9B:
undetectable		 4x1yB-2bg9B:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 7 THR E 468
ALA E 464
LEU E 460
SER E 459
 None
 0.99A 5bojB-2bg9E:
undetectable		 5bojB-2bg9E:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		3 / 3 ASN C  97
LEU C  42
PHE C 217
 None
 0.81A 5dsgA-2bg9C:
undetectable		 5dsgA-2bg9C:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 12 VAL A 413
LEU A 250
PHE A 225
LEU A 253
THR A 254
 None
 1.21A 5hnwB-2bg9A:
undetectable		 5hnwB-2bg9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		4 / 5 ILE A 417
LEU A 253
HIS A 299
VAL A 295
 None
 1.23A 5jmnB-2bg9A:
2.1		 5jmnB-2bg9A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		4 / 7 VAL C  56
ALA C 124
LEU C  37
LEU C  35
 None
 0.67A 5jq7A-2bg9C:
undetectable		 5jq7A-2bg9C:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata) 		6 / 12 LEU B 230
ILE B 233
GLY C 307
LEU B 263
LEU B 259
LEU B 237
 None
 1.47A 5nfjA-2bg9B:
undetectable		 5nfjA-2bg9B:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		3 / 3 VAL C  24
VAL C  31
GLN C 213
 None
 0.68A 5qglA-2bg9C:
undetectable		 5qglA-2bg9C:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata) 		4 / 4 VAL C  24
VAL C  31
TYR C 153
GLN C 213
 None
 1.07A 5qgqA-2bg9C:
undetectable		 5qgqA-2bg9C:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata) 		4 / 6 ILE C 460
ILE B 233
LEU C 310
HIS C 313
 None
 1.03A 5vkqA-2bg9C:
3.9
5vkqB-2bg9C:
3.9		 5vkqA-2bg9C:
11.88
5vkqB-2bg9C:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata) 		4 / 6 ILE C 460
ILE B 233
LEU C 310
HIS C 313
 None
 1.03A 5vkqB-2bg9C:
3.9
5vkqC-2bg9C:
3.8		 5vkqB-2bg9C:
11.88
5vkqC-2bg9C:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata) 		4 / 6 ILE C 460
ILE B 233
LEU C 310
HIS C 313
 None
 1.01A 5vkqC-2bg9C:
3.8
5vkqD-2bg9C:
3.8		 5vkqC-2bg9C:
11.88
5vkqD-2bg9C:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN
(Torpedo
marmorata;
Torpedo
marmorata) 		4 / 6 ILE C 460
ILE B 233
LEU C 310
HIS C 313
 None
 1.01A 5vkqA-2bg9C:
3.9
5vkqD-2bg9C:
3.8		 5vkqA-2bg9C:
11.88
5vkqD-2bg9C:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		3 / 3 GLY E 181
THR E 178
GLU E 179
 None
 0.57A 6b58A-2bg9E:
5.9		 6b58A-2bg9E:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
(Torpedo
marmorata) 		5 / 12 LEU A  35
GLY A  34
VAL A 156
ILE A  31
ASP A  30
 None
 1.19A 6bxnB-2bg9A:
undetectable		 6bxnB-2bg9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN
(Torpedo
marmorata) 		4 / 7 TRP E 183
CSS E 141
TYR E 133
LEU E  39
 None
 1.14A 6cnkB-2bg9E:
19.0
6cnkC-2bg9E:
17.1		 6cnkB-2bg9E:
11.62
6cnkC-2bg9E:
11.40