SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bh5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_E_THAE5_1 (LIVER CARBOXYLESTERASE I)	2bh5	CYTOCHROME C-550 (Paracoccus versutus)	5 / 12	GLY X 44 VAL X 70 SER X 119 VAL X 112 LEU X 76	None	1.43A	1mx1E-2bh5X: undetectable	1mx1E-2bh5X: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X1L_A_ADNA601_1 (METHIONYL-TRNA SYNTHETASE)	2bh5	CYTOCHROME C-550 (Paracoccus versutus)	5 / 11	ALA X 48 HIS X 19 GLY X 36 GLY X 56 ILE X 59	HEC X1123 (-4.4A) HEC X1123 (-3.1A) HEC X1123 ( 3.9A) HEC X1123 (-3.7A) HEC X1123 (-4.3A)	1.16A	2x1lA-2bh5X: undetectable	2x1lA-2bh5X: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HZN_D_ACTD229_0 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	2bh5	CYTOCHROME C-550 (Paracoccus versutus)	4 / 4	ASP X 4 GLY X 8 LYS X 7 GLU X 11	None	1.42A	3hznD-2bh5X: undetectable	3hznD-2bh5X: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KHP_A_PARA1606_1 (16S RIBOSOMAL RNA 30S RIBOSOMAL PROTEIN S9 30S RIBOSOMAL PROTEIN S10)	2bh5	CYTOCHROME C-550 (Paracoccus versutus)	3 / 3	TYR X 55 ARG X 45 SER X 49	HEC X1123 (-4.5A) HEC X1123 (-4.0A) None	0.82A	4khpI-2bh5X: undetectable 4khpJ-2bh5X: undetectable	4khpI-2bh5X: 22.46 4khpJ-2bh5X: 19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LF7_A_PARA1817_1 (16S RRNA RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S10)	2bh5	CYTOCHROME C-550 (Paracoccus versutus)	3 / 3	TYR X 55 ARG X 45 SER X 49	HEC X1123 (-4.5A) HEC X1123 (-4.0A) None	0.75A	4lf7I-2bh5X: undetectable 4lf7J-2bh5X: undetectable	4lf7I-2bh5X: 23.74 4lf7J-2bh5X: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LF8_A_PARA1817_1 (16S RRNA RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S10)	2bh5	CYTOCHROME C-550 (Paracoccus versutus)	3 / 3	TYR X 55 ARG X 45 SER X 49	HEC X1123 (-4.5A) HEC X1123 (-4.0A) None	0.75A	4lf8I-2bh5X: undetectable 4lf8J-2bh5X: undetectable	4lf8I-2bh5X: 23.74 4lf8J-2bh5X: 18.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MX1_E_THAE5_1","LIVER CARBOXYLESTERASE I","2bh5","CYTOCHROME C-550","Paracoccus versutus",5,"GLY X  44;VAL X  70;SER X 119;VAL X 112;LEU X  76","None","1.43A","1mx1E-2bh5X:undetectable","1mx1E-2bh5X:16.56"],["2X1L_A_ADNA601_1","METHIONYL-TRNA SYNTHETASE","2bh5","CYTOCHROME C-550","Paracoccus versutus",5,"ALA X  48;HIS X  19;GLY X  36;GLY X  56;ILE X  59","HEC X1123 (-4.4A);HEC X1123 (-3.1A);HEC X1123 ( 3.9A);HEC X1123 (-3.7A);HEC X1123 (-4.3A)","1.16A","2x1lA-2bh5X:undetectable","2x1lA-2bh5X:17.20"],["3HZN_D_ACTD229_0","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","2bh5","CYTOCHROME C-550","Paracoccus versutus",4,"ASP X   4;GLY X   8;LYS X   7;GLU X  11","None","1.42A","3hznD-2bh5X:undetectable","3hznD-2bh5X:22.08"],["4KHP_A_PARA1606_1","16S RIBOSOMAL RNA;30S RIBOSOMAL PROTEIN S9;30S RIBOSOMAL PROTEIN S10","2bh5","CYTOCHROME C-550","Paracoccus versutus",3,"TYR X  55;ARG X  45;SER X  49","HEC X1123 (-4.5A);HEC X1123 (-4.0A);None","0.82A","4khpI-2bh5X:undetectable;4khpJ-2bh5X:undetectable","4khpI-2bh5X:22.46;4khpJ-2bh5X:19.40"],["4LF7_A_PARA1817_1","16S RRNA;RIBOSOMAL PROTEIN S9;RIBOSOMAL PROTEIN S10","2bh5","CYTOCHROME C-550","Paracoccus versutus",3,"TYR X  55;ARG X  45;SER X  49","HEC X1123 (-4.5A);HEC X1123 (-4.0A);None","0.75A","4lf7I-2bh5X:undetectable;4lf7J-2bh5X:undetectable","4lf7I-2bh5X:23.74;4lf7J-2bh5X:18.31"],["4LF8_A_PARA1817_1","16S RRNA;RIBOSOMAL PROTEIN S9;RIBOSOMAL PROTEIN S10","2bh5","CYTOCHROME C-550","Paracoccus versutus",3,"TYR X  55;ARG X  45;SER X  49","HEC X1123 (-4.5A);HEC X1123 (-4.0A);None","0.75A","4lf8I-2bh5X:undetectable;4lf8J-2bh5X:undetectable","4lf8I-2bh5X:23.74;4lf8J-2bh5X:18.31"]]