SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 2bhn XPF ENDONUCLEASE
(Aeropyrum
pernix) 		4 / 5 ILE A 223
PHE A 198
PHE A 199
ILE A 180
 None
 1.16A 2hjhA-2bhnA:
undetectable		 2hjhA-2bhnA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 2bhn XPF ENDONUCLEASE
(Aeropyrum
pernix) 		5 / 10 THR A 130
VAL A  32
PRO A  33
ILE A 140
VAL A 139
 None
 1.04A 2nnjA-2bhnA:
undetectable		 2nnjA-2bhnA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 2bhn XPF ENDONUCLEASE
(Aeropyrum
pernix) 		3 / 3 LEU A 127
LEU A  85
PHE A  69
 None
 0.50A 2pgrA-2bhnA:
undetectable		 2pgrA-2bhnA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 2bhn XPF ENDONUCLEASE
(Aeropyrum
pernix) 		4 / 6 GLY A  51
GLU A  62
ASP A  68
ASP A  24
 None
 0.95A 3vywC-2bhnA:
undetectable		 3vywC-2bhnA:
23.05