SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 8 ILE A  31
LEU A 206
GLU A  24
ALA A  23
VAL A  29
 None
 1.36A 1a29A-2bi7A:
undetectable		 1a29A-2bi7A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 11 THR A 362
VAL A 341
GLY A 342
THR A 355
VAL A  17
 None
None
FAD  A1385 (-3.4A)
FAD  A1385 (-3.4A)
None
 1.27A 1akdA-2bi7A:
undetectable		 1akdA-2bi7A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 10 LEU A   7
VAL A 213
ILE A  38
GLY A  39
GLY A  12
 None
None
None
None
FAD  A1385 (-3.4A)
 1.03A 1k6cA-2bi7A:
undetectable		 1k6cA-2bi7A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  12
ALA A  11
ILE A 211
GLY A  19
ILE A  18
 FAD  A1385 (-3.4A)
None
None
None
None
 0.96A 1sguB-2bi7A:
undetectable		 1sguB-2bi7A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 11 THR A 362
VAL A 341
GLY A 342
THR A 355
VAL A  17
 None
None
FAD  A1385 (-3.4A)
FAD  A1385 (-3.4A)
None
 1.28A 2a1nA-2bi7A:
undetectable		 2a1nA-2bi7A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  12
ALA A  11
VAL A 213
VAL A  29
ILE A  31
 FAD  A1385 (-3.4A)
None
None
None
None
 0.79A 2avvB-2bi7A:
undetectable		 2avvB-2bi7A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  12
ALA A  11
VAL A 213
VAL A  29
ILE A  31
 FAD  A1385 (-3.4A)
None
None
None
None
 0.85A 2o4lB-2bi7A:
undetectable		 2o4lB-2bi7A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 345
GLY A  12
GLY A  10
GLY A 234
ILE A 202
 None
FAD  A1385 (-3.4A)
FAD  A1385 (-3.1A)
FAD  A1385 (-3.5A)
None
 1.03A 2oxtA-2bi7A:
3.5		 2oxtA-2bi7A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 8 ILE A 205
SER A  42
TYR A  72
SER A  14
 None
FAD  A1385 ( 3.8A)
None
FAD  A1385 (-2.6A)
 0.97A 2zw9B-2bi7A:
undetectable		 2zw9B-2bi7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 6 LEU A 325
GLY A 320
LEU A 329
SER A 330
 None
 0.94A 3aiaA-2bi7A:
1.2		 3aiaA-2bi7A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 8 GLY A  12
ALA A  11
VAL A 213
GLY A  19
ILE A  18
 FAD  A1385 (-3.4A)
None
None
None
None
 1.21A 3ekpA-2bi7A:
undetectable		 3ekpA-2bi7A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  12
ALA A  11
VAL A 213
VAL A  29
ILE A  31
 FAD  A1385 (-3.4A)
None
None
None
None
 0.89A 3el1B-2bi7A:
undetectable		 3el1B-2bi7A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 9 ILE A 104
ILE A 121
LYS A 124
LEU A 147
GLU A 146
 None
 1.45A 3f78B-2bi7A:
2.5		 3f78B-2bi7A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		6 / 12 MET A 201
ILE A   8
GLY A  15
ILE A 356
ALA A  11
VAL A  29
 None
 1.30A 3fpjA-2bi7A:
3.3		 3fpjA-2bi7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 197
VAL A 213
GLY A  39
SER A  42
ILE A 202
 None
None
None
FAD  A1385 ( 3.8A)
None
 1.15A 3k13A-2bi7A:
undetectable		 3k13A-2bi7A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 197
VAL A 213
GLY A  39
SER A  42
ILE A 202
 None
None
None
FAD  A1385 ( 3.8A)
None
 1.14A 3k13B-2bi7A:
undetectable		 3k13B-2bi7A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 197
VAL A 213
GLY A  39
SER A  42
ILE A 202
 None
None
None
FAD  A1385 ( 3.8A)
None
 1.13A 3k13C-2bi7A:
undetectable		 3k13C-2bi7A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 10 PHE A 152
ALA A 139
PHE A 142
ILE A 121
CYH A 272
 None
 1.21A 3qpsA-2bi7A:
undetectable		 3qpsA-2bi7A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  12
ALA A  11
VAL A 213
VAL A  29
ILE A  31
 FAD  A1385 (-3.4A)
None
None
None
None
 0.88A 3tkwB-2bi7A:
undetectable		 3tkwB-2bi7A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 8 ARG A 280
TYR A 299
GLU A 301
HIS A 284
 None
 1.40A 3zmdA-2bi7A:
0.0
3zmdB-2bi7A:
undetectable		 3zmdA-2bi7A:
19.00
3zmdB-2bi7A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		3 / 3 PHE A  13
VAL A 213
ILE A 211
 None
 0.59A 4emaA-2bi7A:
undetectable		 4emaA-2bi7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 8 PHE A 107
ILE A  99
PHE A 108
GLY A 144
 None
 0.89A 4fgjA-2bi7A:
4.3
4fgjB-2bi7A:
4.3		 4fgjA-2bi7A:
20.97
4fgjB-2bi7A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 LEU A 175
VAL A 177
ALA A 150
PHE A 108
PHE A 107
 None
 1.33A 4iaqA-2bi7A:
undetectable		 4iaqA-2bi7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 8 ILE A 143
ILE A 104
ALA A 117
VAL A 177
PRO A 176
 None
 1.23A 4jltA-2bi7A:
undetectable		 4jltA-2bi7A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 8 LEU A 324
LEU A 331
PHE A 239
GLY A 241
 None
 0.78A 4r3aA-2bi7A:
undetectable		 4r3aA-2bi7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		3 / 3 GLU A 138
ALA A 139
PHE A 142
 None
 0.65A 4v1fA-2bi7A:
undetectable		 4v1fA-2bi7A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		3 / 3 GLU A 138
ALA A 139
PHE A 142
 None
 0.67A 4v1fC-2bi7A:
undetectable		 4v1fC-2bi7A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 7 TYR A 259
SER A 296
PHE A 257
GLU A 283
 None
 1.21A 4xzkA-2bi7A:
undetectable		 4xzkA-2bi7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 6 TYR A 249
ARG A 343
GLY A 342
LEU A 344
 None
FAD  A1385 (-4.1A)
FAD  A1385 (-3.4A)
FAD  A1385 ( 4.7A)
 1.29A 5bphA-2bi7A:
4.0		 5bphA-2bi7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 9 THR A 362
VAL A 341
GLY A 342
THR A 355
VAL A  17
 None
None
FAD  A1385 (-3.4A)
FAD  A1385 (-3.4A)
None
 1.28A 5cp4A-2bi7A:
undetectable		 5cp4A-2bi7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		3 / 3 TYR A 302
LYS A 255
LYS A 300
 None
 1.19A 5dbyA-2bi7A:
undetectable		 5dbyA-2bi7A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  19
SER A  14
HIS A  27
VAL A  29
VAL A 213
 None
FAD  A1385 (-2.6A)
None
None
None
 1.11A 5dpdA-2bi7A:
2.8		 5dpdA-2bi7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 6 TYR A 349
ILE A  61
TYR A 185
TYR A 155
 FAD  A1385 (-4.8A)
FAD  A1385 (-4.3A)
None
None
 0.95A 5igyA-2bi7A:
undetectable		 5igyA-2bi7A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 6 TYR A 349
ILE A  61
TYR A 185
TYR A 155
 FAD  A1385 (-4.8A)
FAD  A1385 (-4.3A)
None
None
 1.00A 5ih0A-2bi7A:
undetectable		 5ih0A-2bi7A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		3 / 3 THR A 339
HIS A 229
ASN A 337
 None
 1.00A 5n4tA-2bi7A:
undetectable		 5n4tA-2bi7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  39
SER A  42
 None
None
None
None
FAD  A1385 ( 3.8A)
 1.06A 5vooA-2bi7A:
undetectable		 5vooA-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 VAL A 213
LEU A 215
GLY A  39
SER A  42
ILE A 202
 None
None
None
FAD  A1385 ( 3.8A)
None
 1.18A 5vooA-2bi7A:
undetectable		 5vooA-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  39
SER A  42
 None
None
None
None
FAD  A1385 ( 3.8A)
 1.11A 5vooB-2bi7A:
undetectable		 5vooB-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		6 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  39
SER A  42
ILE A 202
 None
None
None
None
FAD  A1385 ( 3.8A)
None
 1.25A 5vooC-2bi7A:
undetectable		 5vooC-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		6 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  39
SER A  42
ILE A 202
 None
None
None
None
FAD  A1385 ( 3.8A)
None
 1.29A 5vooD-2bi7A:
undetectable		 5vooD-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  40
SER A  42
 None
None
None
FAD  A1385 (-3.1A)
FAD  A1385 ( 3.8A)
 1.18A 5vooD-2bi7A:
undetectable		 5vooD-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		6 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  39
SER A  42
ILE A 202
 None
None
None
None
FAD  A1385 ( 3.8A)
None
 1.35A 5vooE-2bi7A:
undetectable		 5vooE-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		6 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  39
SER A  42
ILE A 202
 None
None
None
None
FAD  A1385 ( 3.8A)
None
 1.33A 5vooF-2bi7A:
undetectable		 5vooF-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 197
VAL A 213
LEU A 215
GLY A  39
SER A  42
 None
None
None
None
FAD  A1385 ( 3.8A)
 1.06A 5vopA-2bi7A:
undetectable		 5vopA-2bi7A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  10
ALA A  16
ASP A  33
GLU A 218
PHE A 219
 FAD  A1385 (-3.1A)
None
FAD  A1385 (-2.7A)
None
None
 1.09A 5x6yC-2bi7A:
1.1		 5x6yC-2bi7A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		3 / 3 GLY A 295
THR A  50
GLU A  49
 None
 0.47A 6b58A-2bi7A:
8.0		 6b58A-2bi7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 2bi7 UDP-GALACTOPYRANOSE
MUTASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A 234
LEU A 344
GLY A 241
TYR A 242
 FAD  A1385 (-3.5A)
FAD  A1385 ( 4.7A)
None
None
 0.68A 6nm4A-2bi7A:
undetectable		 6nm4A-2bi7A:
20.33