SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.45A 1uw6A-2bj0A:
24.8
1uw6B-2bj0A:
25.8		 1uw6A-2bj0A:
43.00
1uw6B-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_B_NCTB1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 9 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.44A 1uw6B-2bj0A:
25.8
1uw6C-2bj0A:
25.6		 1uw6B-2bj0A:
43.00
1uw6C-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.48A 1uw6D-2bj0A:
25.0
1uw6E-2bj0A:
25.2		 1uw6D-2bj0A:
43.00
1uw6E-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_F_NCTF1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 10 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.45A 1uw6F-2bj0A:
25.1
1uw6G-2bj0A:
25.3		 1uw6F-2bj0A:
43.00
1uw6G-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.47A 1uw6G-2bj0A:
25.3
1uw6H-2bj0A:
25.4		 1uw6G-2bj0A:
43.00
1uw6H-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_H_NCTH1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 10 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.44A 1uw6H-2bj0A:
25.4
1uw6I-2bj0A:
25.4		 1uw6H-2bj0A:
43.00
1uw6I-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_J_NCTJ1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 9 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.41A 1uw6F-2bj0A:
25.1
1uw6J-2bj0A:
25.5		 1uw6F-2bj0A:
43.00
1uw6J-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_M_NCTM1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 10 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.47A 1uw6M-2bj0A:
25.3
1uw6N-2bj0A:
25.7		 1uw6M-2bj0A:
43.00
1uw6N-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_N_NCTN1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 10 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.41A 1uw6N-2bj0A:
25.7
1uw6O-2bj0A:
25.4		 1uw6N-2bj0A:
43.00
1uw6O-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_O_NCTO1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 9 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.44A 1uw6K-2bj0A:
24.8
1uw6O-2bj0A:
25.4		 1uw6K-2bj0A:
43.00
1uw6O-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.44A 1uw6P-2bj0A:
25.1
1uw6Q-2bj0A:
25.5		 1uw6P-2bj0A:
43.00
1uw6Q-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_Q_NCTQ1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 10 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.44A 1uw6Q-2bj0A:
25.5
1uw6R-2bj0A:
25.2		 1uw6Q-2bj0A:
43.00
1uw6R-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_S_NCTS1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 10 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.46A 1uw6S-2bj0A:
25.4
1uw6T-2bj0A:
25.2		 1uw6S-2bj0A:
43.00
1uw6T-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.44A 1uw6P-2bj0A:
25.1
1uw6T-2bj0A:
25.2		 1uw6P-2bj0A:
43.00
1uw6T-2bj0A:
43.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WNC_A_TKTA300_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		6 / 10 TYR A  88
TRP A 142
TYR A 184
CSS A 186
CSS A 187
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-3.4A)
CXS  A1204 (-3.6A)
CXS  A1204 (-4.7A)
 0.80A 2wncA-2bj0A:
22.5
2wncE-2bj0A:
18.8		 2wncA-2bj0A:
31.49
2wncE-2bj0A:
31.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WNC_A_TKTA300_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 10 TYR A  88
TRP A 142
TYR A 184
CSS A 186
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-3.4A)
CXS  A1204 (-4.7A)
 1.21A 2wncA-2bj0A:
22.5
2wncE-2bj0A:
18.8		 2wncA-2bj0A:
31.49
2wncE-2bj0A:
31.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_A_ACHA1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 6 TYR A  88
TRP A 142
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.55A 2xz5A-2bj0A:
24.8
2xz5B-2bj0A:
24.7		 2xz5A-2bj0A:
31.30
2xz5B-2bj0A:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 7 TYR A  88
TRP A 142
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.55A 2xz5B-2bj0A:
24.7
2xz5E-2bj0A:
24.6		 2xz5B-2bj0A:
31.30
2xz5E-2bj0A:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.56A 2xz5A-2bj0A:
24.8
2xz5C-2bj0A:
24.6		 2xz5A-2bj0A:
31.30
2xz5C-2bj0A:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.56A 2xz5C-2bj0A:
24.6
2xz5D-2bj0A:
24.7		 2xz5C-2bj0A:
31.30
2xz5D-2bj0A:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 7 TYR A  88
TRP A 142
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.55A 2xz5D-2bj0A:
24.7
2xz5E-2bj0A:
24.6		 2xz5D-2bj0A:
31.30
2xz5E-2bj0A:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 12 ILE A 137
LEU A  33
ILE A 196
ILE A  36
PHE A 120
 None
 1.14A 2ygnA-2bj0A:
undetectable		 2ygnA-2bj0A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 6 LEU A   7
GLY A  12
LEU A  64
SER A  63
 None
 0.83A 3aiaA-2bj0A:
undetectable		 3aiaA-2bj0A:
23.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 7 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.66A 3wipA-2bj0A:
25.1
3wipB-2bj0A:
24.6		 3wipA-2bj0A:
40.44
3wipB-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.71A 3wipB-2bj0A:
24.6
3wipC-2bj0A:
25.2		 3wipB-2bj0A:
40.44
3wipC-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.69A 3wipC-2bj0A:
25.2
3wipD-2bj0A:
25.2		 3wipC-2bj0A:
40.44
3wipD-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.70A 3wipD-2bj0A:
25.2
3wipE-2bj0A:
25.1		 3wipD-2bj0A:
40.44
3wipE-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.76A 3wipA-2bj0A:
25.1
3wipE-2bj0A:
25.1		 3wipA-2bj0A:
40.44
3wipE-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 7 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.66A 3wipF-2bj0A:
24.5
3wipG-2bj0A:
25.9		 3wipF-2bj0A:
40.44
3wipG-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.68A 3wipG-2bj0A:
25.9
3wipH-2bj0A:
24.8		 3wipG-2bj0A:
40.44
3wipH-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_H_ACHH301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 9 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.64A 3wipH-2bj0A:
24.8
3wipI-2bj0A:
25.4		 3wipH-2bj0A:
40.44
3wipI-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_I_ACHI301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 9 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.85A 3wipI-2bj0A:
25.4
3wipJ-2bj0A:
25.0		 3wipI-2bj0A:
40.44
3wipJ-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.66A 3wipF-2bj0A:
24.5
3wipJ-2bj0A:
25.0		 3wipF-2bj0A:
40.44
3wipJ-2bj0A:
40.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.32A 4aftD-2bj0A:
24.4
4aftE-2bj0A:
19.0		 4aftD-2bj0A:
31.30
4aftE-2bj0A:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.34A 4bqtC-2bj0A:
24.5
4bqtD-2bj0A:
24.4		 4bqtC-2bj0A:
31.30
4bqtD-2bj0A:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.75A 5kxiA-2bj0A:
22.6
5kxiB-2bj0A:
21.8		 5kxiA-2bj0A:
19.49
5kxiB-2bj0A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.76A 5kxiD-2bj0A:
22.4
5kxiE-2bj0A:
21.7		 5kxiD-2bj0A:
19.49
5kxiE-2bj0A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		3 / 3 PHE A 170
ASP A 171
LYS A 203
 None
 0.89A 6awtD-2bj0A:
undetectable		 6awtD-2bj0A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 8 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.76A 6cnjD-2bj0A:
21.6
6cnjE-2bj0A:
10.7		 6cnjD-2bj0A:
17.44
6cnjE-2bj0A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_A_NCTA405_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 6 TYR A  88
TRP A 142
THR A 143
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.7A)
 0.70A 6cnkA-2bj0A:
21.5
6cnkB-2bj0A:
15.1		 6cnkA-2bj0A:
17.44
6cnkB-2bj0A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 7 TYR A  88
TRP A 142
CSS A 186
CSS A 187
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-3.4A)
CXS  A1204 (-3.6A)
CXS  A1204 (-4.7A)
 0.68A 6cnkB-2bj0A:
15.1
6cnkC-2bj0A:
20.7		 6cnkB-2bj0A:
17.44
6cnkC-2bj0A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		4 / 7 TYR A  88
TRP A 142
CSS A 187
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 (-3.6A)
CXS  A1204 (-4.7A)
 1.28A 6cnkB-2bj0A:
15.1
6cnkC-2bj0A:
20.7		 6cnkB-2bj0A:
17.44
6cnkC-2bj0A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_D_NCTD401_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 2bj0 ACETYLCHOLINE-BINDIN
G PROTEIN
(Bulinus
truncatus) 		5 / 9 TYR A  88
TRP A 142
THR A 143
TYR A 184
TYR A 191
 None
CXS  A1204 (-3.6A)
CXS  A1204 ( 4.7A)
CXS  A1204 (-4.6A)
CXS  A1204 (-4.7A)
 0.84A 6cnkD-2bj0A:
21.3
6cnkE-2bj0A:
9.9		 6cnkD-2bj0A:
17.44
6cnkE-2bj0A:
15.08