SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H1D_A_SAMA301_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 4 SER A1079
GLU A1070
SER A1037
ASP A1274
 None
MG  A2279 ( 2.6A)
None
None
 1.26A 1h1dA-2bjiA:
0.0		 1h1dA-2bjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		5 / 12 VAL A1193
LEU A1235
ALA A1252
ASN A1199
VAL A1148
 None
 1.08A 1sa1A-2bjiA:
undetectable
1sa1B-2bjiA:
undetectable		 1sa1A-2bjiA:
20.96
1sa1B-2bjiA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 5 SER A1079
GLU A1070
SER A1037
ASP A1274
 None
MG  A2279 ( 2.6A)
None
None
 1.27A 1vidA-2bjiA:
undetectable		 1vidA-2bjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		5 / 12 ALA A1210
ASP A1209
ILE A1187
GLY A1189
ILE A1262
 None
 1.10A 2o4kA-2bjiA:
undetectable		 2o4kA-2bjiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.13A 2obvA-2bjiA:
undetectable		 2obvA-2bjiA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.14A 2p02A-2bjiA:
undetectable		 2p02A-2bjiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 7 ILE A1109
SER A1057
TYR A1062
TYR A1011
 None
 1.43A 2xz5D-2bjiA:
undetectable
2xz5E-2bjiA:
undetectable		 2xz5D-2bjiA:
19.16
2xz5E-2bjiA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 6 SER A1079
GLU A1070
SER A1037
ASP A1274
 None
MG  A2279 ( 2.6A)
None
None
 1.24A 2zvjA-2bjiA:
undetectable		 2zvjA-2bjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		5 / 12 THR A1161
VAL A1238
ALA A1210
GLU A1213
ILE A1269
 None
 1.21A 3dl9B-2bjiA:
undetectable		 3dl9B-2bjiA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_B_TMQB612_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		5 / 9 VAL A1160
ALA A1210
ILE A1154
ILE A1190
TYR A1212
 None
 1.49A 3hbbB-2bjiA:
undetectable		 3hbbB-2bjiA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 7 PHE A1098
VAL A1105
VAL A1099
GLY A1094
 None
 1.04A 3kmoB-2bjiA:
undetectable		 3kmoB-2bjiA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		5 / 12 GLY A1094
VAL A1107
ALA A1197
ALA A1196
LEU A1042
 None
 0.98A 3mteB-2bjiA:
undetectable		 3mteB-2bjiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		5 / 12 ALA A1204
GLY A1223
GLY A1225
ILE A1226
VAL A1122
 None
 1.12A 3o7wA-2bjiA:
undetectable		 3o7wA-2bjiA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		5 / 12 GLY A1094
VAL A1107
ALA A1197
ALA A1196
LEU A1042
 None
 0.98A 3p2kC-2bjiA:
undetectable		 3p2kC-2bjiA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 5 ASP A1220
GLU A1213
GLY A1215
ASP A1274
 MG  A2278 (-3.0A)
None
None
None
 1.40A 3w9tD-2bjiA:
undetectable		 3w9tD-2bjiA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.12A 4kttA-2bjiA:
undetectable		 4kttA-2bjiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.15A 4kttC-2bjiA:
undetectable		 4kttC-2bjiA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.09A 4ndnA-2bjiA:
undetectable		 4ndnA-2bjiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 7 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.15A 4ndnC-2bjiA:
undetectable		 4ndnC-2bjiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 7 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.19A 4odjA-2bjiA:
undetectable		 4odjA-2bjiA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.09A 5a1iA-2bjiA:
undetectable		 5a1iA-2bjiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 7 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.09A 5a1iA-2bjiA:
undetectable		 5a1iA-2bjiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 5 SER A1079
GLU A1070
SER A1037
ASP A1274
 None
MG  A2279 ( 2.6A)
None
None
 1.27A 5fhrA-2bjiA:
undetectable		 5fhrA-2bjiA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		3 / 3 ALA A1197
VAL A1160
TYR A1211
 None
 0.72A 5zmqH-2bjiA:
undetectable		 5zmqH-2bjiA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.20A 6fbnB-2bjiA:
undetectable		 6fbnB-2bjiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.11A 6fboA-2bjiA:
undetectable		 6fboA-2bjiA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.12A 6fcbA-2bjiA:
undetectable		 6fcbA-2bjiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.11A 6fcdA-2bjiA:
undetectable		 6fcdA-2bjiA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2bji INOSITOL-1(OR
4)-MONOPHOSPHATASE
(Bos
taurus) 		4 / 7 PRO A1091
ASP A1090
SER A1165
ASP A1047
 MG  A2277 ( 4.8A)
MG  A2278 ( 2.5A)
None
None
 1.09A 6g6rA-2bjiA:
undetectable		 6g6rA-2bjiA:
20.80