SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bjq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 2bjq MFP2A
(Ascaris
suum) 		3 / 3 ARG A 167
GLU A   7
GLN A 112
 None
 1.00A 2p16A-2bjqA:
undetectable		 2p16A-2bjqA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 2bjq MFP2A
(Ascaris
suum) 		4 / 4 GLU A  98
ARG A 100
ASN A 107
ASP A 104
 None
 1.50A 2zq9A-2bjqA:
undetectable		 2zq9A-2bjqA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2bjq MFP2A
(Ascaris
suum) 		5 / 12 GLY A 134
GLY A  46
ILE A 123
MET A 162
GLU A  65
 None
 1.16A 3ckkA-2bjqA:
undetectable		 3ckkA-2bjqA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2bjq MFP2A
(Ascaris
suum) 		4 / 5 PRO A  86
ASP A  85
ILE A 178
VAL A 263
 None
 1.15A 4hytA-2bjqA:
undetectable		 4hytA-2bjqA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 2bjq MFP2A
(Ascaris
suum) 		4 / 6 ALA A  48
GLN A 260
SER A 258
PRO A  23
 None
 1.03A 5c6pA-2bjqA:
undetectable		 5c6pA-2bjqA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2bjq MFP2A
(Ascaris
suum) 		4 / 5 TYR A  33
TRP A  49
LEU A 220
LEU A 186
 None
 1.33A 5eshA-2bjqA:
0.0		 5eshA-2bjqA:
20.18