SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bjr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2bjr MFP2B
(Ascaris
suum) 		4 / 8 LEU A 275
VAL A 211
LEU A 272
ALA A 196
 None
 0.93A 1fiqC-2bjrA:
undetectable		 1fiqC-2bjrA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 2bjr MFP2B
(Ascaris
suum) 		4 / 6 ILE A 163
ARG A 165
LEU A  80
ASP A   9
 None
 1.03A 2rlfA-2bjrA:
undetectable
2rlfD-2bjrA:
undetectable		 2rlfA-2bjrA:
15.98
2rlfD-2bjrA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 2bjr MFP2B
(Ascaris
suum) 		5 / 12 ILE A 244
GLY A 326
GLY A 242
ALA A 253
ALA A 328
 None
 1.07A 2yvlA-2bjrA:
undetectable		 2yvlA-2bjrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 2bjr MFP2B
(Ascaris
suum) 		5 / 12 ILE A 244
GLY A 326
GLY A 242
ALA A 253
ALA A 328
 None
 1.08A 2yvlB-2bjrA:
undetectable		 2yvlB-2bjrA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2bjr MFP2B
(Ascaris
suum) 		3 / 3 PRO A 226
LEU A 218
GLN A 228
 None
 0.50A 3hznG-2bjrA:
undetectable
3hznH-2bjrA:
undetectable		 3hznG-2bjrA:
20.68
3hznH-2bjrA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 2bjr MFP2B
(Ascaris
suum) 		5 / 11 LEU A  73
GLY A  47
ALA A  36
ILE A  16
ILE A  77
 None
 0.90A 3s45B-2bjrA:
undetectable		 3s45B-2bjrA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2bjr MFP2B
(Ascaris
suum) 		5 / 12 LEU A  73
GLY A  47
ALA A  36
ILE A  16
ILE A  77
 None
 0.86A 3s54A-2bjrA:
undetectable		 3s54A-2bjrA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2bjr MFP2B
(Ascaris
suum) 		4 / 8 GLY A 259
GLY A 341
GLU A 261
TYR A 262
 None
 0.89A 4fgzA-2bjrA:
undetectable		 4fgzA-2bjrA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2bjr MFP2B
(Ascaris
suum) 		4 / 8 LEU A 121
GLU A 124
ALA A 129
LEU A 131
 None
 0.90A 4iizB-2bjrA:
undetectable		 4iizB-2bjrA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 2bjr MFP2B
(Ascaris
suum) 		4 / 6 ALA A  49
GLN A 270
SER A 268
PRO A  24
 None
 0.88A 5c6pA-2bjrA:
undetectable		 5c6pA-2bjrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 2bjr MFP2B
(Ascaris
suum) 		4 / 8 GLY A 326
GLU A 343
ILE A 312
GLN A  31
 None
 1.07A 5vlmD-2bjrA:
undetectable		 5vlmD-2bjrA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 2bjr MFP2B
(Ascaris
suum) 		5 / 12 PHE A 255
GLY A 242
VAL A 303
GLY A 338
ALA A 335
 None
 1.10A 6c2mB-2bjrA:
undetectable		 6c2mB-2bjrA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 2bjr MFP2B
(Ascaris
suum) 		5 / 12 LEU A  73
GLY A  47
ALA A  36
ILE A  16
ILE A  77
 None
 0.93A 6dh3A-2bjrA:
undetectable		 6dh3A-2bjrA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 2bjr MFP2B
(Ascaris
suum) 		4 / 4 ARG A 243
GLU A 224
GLU A 261
ARG A 263
 None
 1.13A 6fk2A-2bjrA:
undetectable		 6fk2A-2bjrA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2bjr MFP2B
(Ascaris
suum) 		4 / 8 HIS A  46
ARG A 165
ASP A   9
GLU A   8
 None
 1.15A 6mn4C-2bjrA:
undetectable		 6mn4C-2bjrA:
20.49