SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		6 / 12 ILE A  56
TYR A  83
VAL A  85
ILE A  98
ASN A 100
LEU A 143
 None
 0.81A 1fm4A-2bk0A:
23.2		 1fm4A-2bk0A:
38.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		6 / 12 PHE A  23
TYR A  83
VAL A  85
ILE A  98
ASN A 100
LEU A 143
 None
 0.69A 1fm4A-2bk0A:
23.2		 1fm4A-2bk0A:
38.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		5 / 12 PHE A  23
VAL A  27
VAL A  85
ILE A  98
ASN A 100
 None
 1.26A 1fm4A-2bk0A:
23.2		 1fm4A-2bk0A:
38.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		4 / 7 LEU A   8
PHE A  23
VAL A  14
SER A 112
 None
 1.11A 1wrlA-2bk0A:
undetectable
1wrlB-2bk0A:
undetectable		 1wrlA-2bk0A:
24.81
1wrlB-2bk0A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		4 / 7 PHE A 120
ILE A  90
VAL A  85
TYR A  83
 None
 0.89A 3p6hA-2bk0A:
2.1		 3p6hA-2bk0A:
23.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		5 / 12 ASP A  28
ILE A  56
TYR A  83
VAL A  85
ILE A  98
 None
 0.87A 4a84A-2bk0A:
22.9		 4a84A-2bk0A:
40.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		5 / 12 ILE A  56
TYR A  83
VAL A  85
ILE A  98
LEU A 143
 None
 0.88A 4a84A-2bk0A:
22.9		 4a84A-2bk0A:
40.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		5 / 12 VAL A  24
ASP A  82
HIS A 101
PRO A  50
GLY A  48
 None
 1.48A 6gnfA-2bk0A:
undetectable		 6gnfA-2bk0A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 2bk0 MAJOR ALLERGEN API G
1
(Apium
graveolens) 		5 / 12 VAL A  24
ASP A  82
HIS A 101
PRO A  50
GLY A  48
 None
 1.46A 6gnfC-2bk0A:
undetectable		 6gnfC-2bk0A:
15.90