SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bk9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 2bk9 CG9734-PA
(Drosophila
melanogaster) 		4 / 6 LEU A 114
ALA A 128
LEU A 117
SER A 121
 None
 1.03A 1ictB-2bk9A:
undetectable		 1ictB-2bk9A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 2bk9 CG9734-PA
(Drosophila
melanogaster) 		5 / 11 PHE A 143
PHE A  31
VAL A 112
TYR A 139
VAL A 138
 None
HEM  A1154 ( 3.9A)
None
None
None
 1.12A 2vcdA-2bk9A:
undetectable		 2vcdA-2bk9A:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2bk9 CG9734-PA
(Drosophila
melanogaster) 		5 / 10 ALA A  62
PHE A  42
HIS A  61
GLY A  24
ILE A  27
 None
HEM  A1154 (-3.0A)
HEM  A1154 (-3.2A)
None
None
 1.11A 2zm7A-2bk9A:
undetectable		 2zm7A-2bk9A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2bk9 CG9734-PA
(Drosophila
melanogaster) 		5 / 10 ALA A  62
PHE A  42
HIS A  61
GLY A  24
ILE A  27
 None
HEM  A1154 (-3.0A)
HEM  A1154 (-3.2A)
None
None
 1.10A 2zm8A-2bk9A:
undetectable		 2zm8A-2bk9A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2bk9 CG9734-PA
(Drosophila
melanogaster) 		5 / 9 LEU A 134
VAL A 101
ILE A 142
LEU A 114
VAL A 112
 CXS  A1155 ( 4.1A)
HEM  A1154 ( 3.8A)
None
None
None
 1.45A 3oxzA-2bk9A:
undetectable		 3oxzA-2bk9A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2bk9 CG9734-PA
(Drosophila
melanogaster) 		5 / 10 ARG A  45
VAL A  47
LEU A  39
LEU A  28
LEU A  52
 None
 1.03A 6f6nA-2bk9A:
undetectable
6f6nB-2bk9A:
undetectable		 6f6nA-2bk9A:
19.59
6f6nB-2bk9A:
20.77