SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 2bka TAT-INTERACTING
PROTEIN TIP30
(Homo
sapiens) 		3 / 3 LEU A  92
LEU A  55
PHE A  72
 NDP  A 506 (-4.3A)
None
NDP  A 506 (-4.5A)
 0.72A 2pgrA-2bkaA:
undetectable		 2pgrA-2bkaA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 2bka TAT-INTERACTING
PROTEIN TIP30
(Homo
sapiens) 		3 / 3 GLU A 151
GLY A 148
SER A 131
 None
 0.70A 4b53B-2bkaA:
undetectable		 4b53B-2bkaA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 2bka TAT-INTERACTING
PROTEIN TIP30
(Homo
sapiens) 		4 / 5 GLU A 176
SER A 197
PRO A 202
SER A 200
 None
 1.45A 4k17B-2bkaA:
2.9		 4k17B-2bkaA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 2bka TAT-INTERACTING
PROTEIN TIP30
(Homo
sapiens) 		4 / 6 ILE A  50
LEU A 118
VAL A  70
SER A 115
 None
 1.22A 6f6jA-2bkaA:
undetectable		 6f6jA-2bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 2bka TAT-INTERACTING
PROTEIN TIP30
(Homo
sapiens) 		3 / 3 ARG A  15
PHE A  44
GLY A  42
 None
 0.81A 6fgdA-2bkaA:
4.1		 6fgdA-2bkaA:
21.17