SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bkk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2bkk DESIGNED ANKYRIN
REPEAT INHIBITOR
AR_3A
(synthetic
construct) 		4 / 6 LEU B 126
ALA B 120
LEU B 117
ALA B 149
 None
 0.91A 2vcvB-2bkkB:
undetectable		 2vcvB-2bkkB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2bkk DESIGNED ANKYRIN
REPEAT INHIBITOR
AR_3A
(synthetic
construct) 		4 / 6 LEU B 126
ALA B 120
LEU B 117
ALA B 149
 None
 0.92A 2vcvK-2bkkB:
undetectable		 2vcvK-2bkkB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 2bkk DESIGNED ANKYRIN
REPEAT INHIBITOR
AR_3A
(synthetic
construct) 		4 / 8 LEU B  86
THR B  82
LEU B 119
SER B  79
 None
 0.76A 4qknA-2bkkB:
undetectable		 4qknA-2bkkB:
16.98