SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bm3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A  91
VAL A 132
PHE A 134
ASN A  86
ALA A  52
 None
 1.11A 1sg9C-2bm3A:
undetectable		 1sg9C-2bm3A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 12 VAL A  72
ILE A  30
ASN A  31
SER A   7
PHE A  36
 None
 1.41A 4c49D-2bm3A:
undetectable		 4c49D-2bm3A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A 146
ASN A  42
ILE A 144
PHE A 150
TYR A 160
 None
None
None
IPA  A1167 ( 4.5A)
None
 1.24A 4kotA-2bm3A:
undetectable		 4kotA-2bm3A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 12 GLY A 146
ASN A  42
ILE A 144
PHE A 150
TYR A 160
 None
None
None
IPA  A1167 ( 4.5A)
None
 1.25A 4kovA-2bm3A:
undetectable		 4kovA-2bm3A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		6 / 12 LEU A 149
LEU A  97
ILE A 117
LEU A  73
ILE A   9
PHE A  36
 None
 1.33A 4odrA-2bm3A:
undetectable
4odrB-2bm3A:
undetectable		 4odrA-2bm3A:
18.82
4odrB-2bm3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 11 PHE A 134
VAL A  28
ILE A 117
ILE A  33
ILE A 157
 None
 0.98A 5hw8E-2bm3A:
undetectable		 5hw8E-2bm3A:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 12 PHE A 134
VAL A  28
ILE A 117
ILE A  33
ILE A 157
 None
 1.02A 5hw8B-2bm3A:
undetectable
5hw8F-2bm3A:
undetectable
5hw8G-2bm3A:
undetectable		 5hw8B-2bm3A:
26.04
5hw8F-2bm3A:
26.04
5hw8G-2bm3A:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 6 SER A 139
GLY A 146
MET A 140
ILE A  92
 None
 1.15A 5j4nA-2bm3A:
undetectable		 5j4nA-2bm3A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 8 LEU A  97
VAL A  72
ARG A  70
ILE A  30
 None
 0.89A 5v0vA-2bm3A:
undetectable		 5v0vA-2bm3A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 8 THR A 130
ASN A  16
PHE A  13
PRO A 165
 None
 1.14A 5v4vA-2bm3A:
undetectable		 5v4vA-2bm3A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		4 / 8 THR A 130
ASN A  16
PHE A  13
PRO A 165
 None
 1.14A 5v4vB-2bm3A:
undetectable		 5v4vB-2bm3A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 11 LEU A  73
GLY A  69
ILE A 116
PHE A  36
ILE A  30
 None
 1.00A 6ebzA-2bm3A:
undetectable		 6ebzA-2bm3A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 11 LEU A  73
GLY A  69
ILE A 116
PHE A  36
ILE A  30
 None
 0.96A 6ebzB-2bm3A:
undetectable		 6ebzB-2bm3A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 11 LEU A  73
GLY A  69
ILE A 116
PHE A  36
ILE A  30
 None
 0.98A 6ebzC-2bm3A:
undetectable		 6ebzC-2bm3A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 11 LEU A  73
GLY A  69
ILE A 116
PHE A  36
ILE A  30
 None
 0.94A 6ebzD-2bm3A:
undetectable		 6ebzD-2bm3A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 11 LEU A  73
GLY A  69
ILE A 116
PHE A  36
ILE A  30
 None
 0.93A 6gp2A-2bm3A:
undetectable		 6gp2A-2bm3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A
(Ruminiclostridiu
m
thermocellum) 		5 / 11 LEU A  73
GLY A  69
ILE A 116
PHE A  36
ILE A  30
 None
 0.87A 6gp2B-2bm3A:
undetectable		 6gp2B-2bm3A:
18.18