SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 131
THR A 112
LEU A 114
LEU A 153
LEU A 109
 None
 1.04A 3ndvA-2bm7A:
undetectable
3ndvB-2bm7A:
undetectable		 3ndvA-2bm7A:
22.19
3ndvB-2bm7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 109
GLY A 131
THR A 112
LEU A 114
LEU A 153
 None
 1.05A 3ndvA-2bm7A:
undetectable
3ndvB-2bm7A:
undetectable		 3ndvA-2bm7A:
22.19
3ndvB-2bm7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 131
THR A 112
LEU A 114
LEU A 153
LEU A 109
 None
 1.06A 3ndvC-2bm7A:
undetectable
3ndvD-2bm7A:
undetectable		 3ndvC-2bm7A:
22.19
3ndvD-2bm7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 109
GLY A 131
THR A 112
LEU A 114
LEU A 153
 None
 1.04A 3ndvC-2bm7A:
undetectable
3ndvD-2bm7A:
undetectable		 3ndvC-2bm7A:
22.19
3ndvD-2bm7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  99
ALA A 132
THR A 134
LEU A 124
 None
 0.99A 3t3zB-2bm7A:
undetectable		 3t3zB-2bm7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 THR A 134
THR A 117
ARG A 100
LEU A 109
LEU A 104
 None
 1.44A 4qynB-2bm7A:
undetectable		 4qynB-2bm7A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 PHE A  74
ALA A  92
THR A  24
LEU A  39
LEU A  59
 None
 1.17A 4qzuC-2bm7A:
undetectable		 4qzuC-2bm7A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 SER A  42
HIS A  44
PHE A  49
TRP A   4
 None
 1.47A 5u6nA-2bm7A:
undetectable		 5u6nA-2bm7A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 2bm7 PENTAPEPTIDE REPEAT
FAMILY PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 132
LEU A 153
VAL A 152
LEU A 124
ASP A 128
 None
 1.14A 5w7pA-2bm7A:
undetectable		 5w7pA-2bm7A:
19.19