SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 7 ILE A 332
GLY A 462
PRO A 326
ASN A 329
 None
 1.01A 1oniG-2bmfA:
undetectable
1oniI-2bmfA:
undetectable		 1oniG-2bmfA:
14.48
1oniI-2bmfA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 12 ILE A 178
LEU A 204
THR A 189
LEU A 280
ILE A 182
 None
 0.98A 1rd7B-2bmfA:
undetectable		 1rd7B-2bmfA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 7 LEU A 204
GLY A 311
ILE A 281
VAL A 208
ILE A 207
 None
 1.10A 2aojB-2bmfA:
undetectable		 2aojB-2bmfA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 7 PHE A 325
ALA A 454
ARG A 458
ASP A 323
 None
 1.08A 2e5dA-2bmfA:
undetectable
2e5dB-2bmfA:
undetectable		 2e5dA-2bmfA:
21.50
2e5dB-2bmfA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 7 ASP A 323
PHE A 325
ALA A 454
ARG A 458
 None
 1.16A 2e5dA-2bmfA:
undetectable
2e5dB-2bmfA:
undetectable		 2e5dA-2bmfA:
21.50
2e5dB-2bmfA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2bmf RNA HELICASE
(Dengue
virus) 		3 / 3 ARG A 387
ASN A 416
THR A 224
 None
 0.86A 2q63A-2bmfA:
undetectable		 2q63A-2bmfA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 7 TRP A 402
TYR A 394
ILE A 383
SER A 411
 None
 1.02A 2xz5A-2bmfA:
undetectable
2xz5B-2bmfA:
undetectable		 2xz5A-2bmfA:
19.80
2xz5B-2bmfA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 7 ILE A 383
SER A 411
TRP A 402
TYR A 394
 None
 1.01A 2xz5D-2bmfA:
undetectable
2xz5E-2bmfA:
undetectable		 2xz5D-2bmfA:
19.80
2xz5E-2bmfA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 10 PRO A 593
ILE A 600
VAL A 441
TRP A 562
LEU A 542
 None
 1.27A 2ze2A-2bmfA:
0.3		 2ze2A-2bmfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 5 ILE A 220
ARG A 297
MET A 314
THR A 315
 None
 1.27A 3abkN-2bmfA:
undetectable
3abkW-2bmfA:
undetectable		 3abkN-2bmfA:
21.62
3abkW-2bmfA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 9 LEU A 204
GLY A 311
ILE A 281
VAL A 208
ILE A 207
 None
 1.13A 3d1yB-2bmfA:
undetectable		 3d1yB-2bmfA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 9 ILE A 383
LEU A 385
ILE A 395
PHE A 390
GLY A 414
 None
 1.44A 3sj4X-2bmfA:
undetectable		 3sj4X-2bmfA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 2bmf RNA HELICASE
(Dengue
virus) 		3 / 3 ARG A 458
ARG A 426
ILE A 332
 None
 0.91A 4b7qC-2bmfA:
undetectable		 4b7qC-2bmfA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 8 ILE A 383
LEU A 385
ILE A 395
PHE A 390
GLY A 414
 None
 1.40A 4hb6A-2bmfA:
undetectable		 4hb6A-2bmfA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 8 ILE A 383
LEU A 385
ILE A 395
PHE A 390
GLY A 414
 None
 1.38A 4hb8A-2bmfA:
undetectable		 4hb8A-2bmfA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 4 THR A 450
ARG A 457
GLU A 412
VAL A 449
 None
 1.28A 4odoC-2bmfA:
0.0		 4odoC-2bmfA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2bmf RNA HELICASE
(Dengue
virus) 		4 / 7 VAL A 275
ILE A 281
ALA A 296
ILE A 282
 None
 0.77A 4uxqA-2bmfA:
undetectable		 4uxqA-2bmfA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 7 PRO A 239
VAL A 257
ILE A 220
VAL A 208
ILE A 212
 None
 1.31A 5bmvC-2bmfA:
undetectable		 5bmvC-2bmfA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2bmf RNA HELICASE
(Dengue
virus) 		3 / 3 ARG A 184
ILE A 182
PHE A 183
 None
 0.53A 5kirA-2bmfA:
undetectable		 5kirA-2bmfA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 2bmf RNA HELICASE
(Dengue
virus) 		5 / 12 PRO A 176
ILE A 182
ILE A 282
LEU A 216
THR A 218
 None
 1.22A 5tiwB-2bmfA:
undetectable		 5tiwB-2bmfA:
21.26