SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bmm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 2bmm THERMOSTABLE
HEMOGLOBIN FROM
THERMOBIFIDA FUSCA
(Thermobifida
fusca) 		5 / 12 ALA A  50
MET A 123
LEU A 130
ARG A  48
LEU A 144
 None
 1.48A 2aa6B-2bmmA:
undetectable		 2aa6B-2bmmA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 2bmm THERMOSTABLE
HEMOGLOBIN FROM
THERMOBIFIDA FUSCA
(Thermobifida
fusca) 		5 / 11 LEU A 130
LEU A 140
LEU A  83
LEU A  49
ARG A  80
 None
 1.10A 2ceoA-2bmmA:
undetectable		 2ceoA-2bmmA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 2bmm THERMOSTABLE
HEMOGLOBIN FROM
THERMOBIFIDA FUSCA
(Thermobifida
fusca) 		4 / 8 MET A  66
LEU A  63
VAL A 154
MET A 151
 None
None
None
HEM  A1157 (-4.6A)
 1.18A 2qd2A-2bmmA:
1.4		 2qd2A-2bmmA:
16.57