SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		4 / 8 THR A 241
GLY A 413
GLY A 296
GLY A 202
 None
 0.61A 1d0vA-2bmoA:
undetectable		 1d0vA-2bmoA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 11 SER A 242
GLY A 162
LEU A 161
GLY A 247
TYR A 147
 None
 1.41A 1iolA-2bmoA:
undetectable		 1iolA-2bmoA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		4 / 8 THR A 241
GLY A 413
GLY A 296
GLY A 202
 None
 0.61A 1jhaA-2bmoA:
undetectable		 1jhaA-2bmoA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		4 / 8 THR A 241
GLY A 413
GLY A 296
GLY A 202
 None
 0.63A 1jhqA-2bmoA:
undetectable		 1jhqA-2bmoA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		4 / 8 THR A 241
GLY A 413
GLY A 296
GLY A 202
 None
 0.63A 1jhvA-2bmoA:
undetectable		 1jhvA-2bmoA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 HIS A 206
ASP A 360
HIS A 211
SER A 308
PHE A 200
 FE  A1441 ( 3.2A)
FE  A1441 ( 2.0A)
FE  A1441 (-3.3A)
None
EDO  A1442 (-3.7A)
 1.28A 1uobA-2bmoA:
undetectable		 1uobA-2bmoA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 11 ILE A 225
GLY A 208
GLY A 204
PRO A 232
ILE A 406
 None
 1.13A 2y7kA-2bmoA:
undetectable		 2y7kA-2bmoA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 GLY A 204
SER A 292
ILE A 289
LEU A 238
GLY A 249
 None
 1.10A 3axzA-2bmoA:
undetectable		 3axzA-2bmoA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		3 / 3 SER A 410
GLY A 249
GLY A 296
 None
 0.49A 3bogA-2bmoA:
undetectable
3bogC-2bmoA:
undetectable		 3bogA-2bmoA:
undetectable
3bogC-2bmoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		3 / 3 THR A 297
SER A 303
PHE A 293
 None
 0.87A 3d4sA-2bmoA:
undetectable		 3d4sA-2bmoA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		3 / 3 HIS A 143
PHE A 329
PHE A 311
 EOH  A1446 (-3.5A)
None
None
 0.78A 3lk0D-2bmoA:
0.0		 3lk0D-2bmoA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		4 / 7 ARG A 216
ALA A 212
TRP A 356
ALA A 226
 None
 1.49A 3tx2A-2bmoA:
undetectable		 3tx2A-2bmoA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		4 / 7 ASN A  36
ARG A  35
GLY A 245
TYR A 244
 None
EDO  A1444 (-3.8A)
None
None
 0.86A 4cp3A-2bmoA:
undetectable
4cp3B-2bmoA:
undetectable		 4cp3A-2bmoA:
14.94
4cp3B-2bmoA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		6 / 12 GLN A 347
ALA A 328
ALA A 310
ALA A 309
THR A 306
LEU A 267
 None
 1.46A 4j6dB-2bmoA:
undetectable		 4j6dB-2bmoA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 9 TRP A 252
ALA A 405
LEU A 238
GLY A 402
ALA A 279
 EOH  A1449 ( 4.1A)
None
None
None
None
 1.46A 4l6va-2bmoA:
undetectable
4l6vf-2bmoA:
0.0		 4l6va-2bmoA:
21.68
4l6vf-2bmoA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.33A 4pfjA-2bmoA:
undetectable		 4pfjA-2bmoA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.30A 5hm8A-2bmoA:
undetectable		 5hm8A-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.30A 5hm8B-2bmoA:
undetectable		 5hm8B-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.30A 5hm8C-2bmoA:
undetectable		 5hm8C-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.29A 5hm8D-2bmoA:
undetectable		 5hm8D-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.29A 5hm8E-2bmoA:
undetectable		 5hm8E-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.30A 5hm8F-2bmoA:
undetectable		 5hm8F-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.30A 5hm8G-2bmoA:
undetectable		 5hm8G-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.29A 5hm8H-2bmoA:
undetectable		 5hm8H-2bmoA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 GLY A 245
TYR A 160
ARG A  35
ALA A 154
ILE A 422
 None
None
EDO  A1444 (-3.8A)
None
None
 1.06A 5igvA-2bmoA:
undetectable		 5igvA-2bmoA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.32A 5m5kC-2bmoA:
undetectable		 5m5kC-2bmoA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.28A 5v96B-2bmoA:
undetectable		 5v96B-2bmoA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 LEU A 305
THR A 326
ASP A 360
GLY A 351
PHE A 200
 None
None
FE  A1441 ( 2.0A)
None
EDO  A1442 (-3.7A)
 1.25A 5v96D-2bmoA:
undetectable		 5v96D-2bmoA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		4 / 6 TYR A 415
LEU A  17
GLU A  28
LEU A  24
 None
 1.31A 5xooA-2bmoA:
undetectable		 5xooA-2bmoA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 2bmo OXYGENASE-ALPHA NBDO
(Comamonas
sp.
JS765) 		5 / 12 GLY A 296
GLY A 247
MET A 240
PHE A 200
THR A 306
 None
None
None
EDO  A1442 (-3.7A)
None
 1.29A 5yf0A-2bmoA:
undetectable		 5yf0A-2bmoA:
21.47