SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2bng MB2760
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  28
TYR A  46
TRP A 120
PHE A  24
ALA A  61
 None
 1.00A 1fe2A-2bngA:
undetectable		 1fe2A-2bngA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2bng MB2760
(Mycobacterium
tuberculosis) 		4 / 8 LEU A  25
ILE A  80
CYH A 107
GLY A 108
 None
 0.70A 1sv9A-2bngA:
undetectable		 1sv9A-2bngA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2bng MB2760
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  28
TYR A  46
TRP A 120
PHE A  24
ALA A  61
 None
 1.09A 2aylA-2bngA:
undetectable		 2aylA-2bngA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2bng MB2760
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  40
ALA A  27
ASP A 122
TYR A  46
 None
 1.25A 2dpzA-2bngA:
undetectable		 2dpzA-2bngA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 2bng MB2760
(Mycobacterium
tuberculosis) 		4 / 6 LEU A  44
LEU A 119
ILE A  54
ARG A  55
 None
 1.12A 2rlfB-2bngA:
undetectable
2rlfC-2bngA:
undetectable		 2rlfB-2bngA:
15.75
2rlfC-2bngA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2bng MB2760
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  28
TYR A  46
TRP A 120
PHE A  24
ALA A  61
 None
 0.99A 3n8xA-2bngA:
undetectable		 3n8xA-2bngA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2bng MB2760
(Mycobacterium
tuberculosis) 		3 / 3 LEU A  25
ASN A  48
LEU A  95
 None
 0.70A 6exiD-2bngA:
undetectable		 6exiD-2bngA:
20.28