SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 11 HIS A  69
VAL A  68
LEU A  92
LEU A 100
THR A 103
 None
 1.11A 1dmyA-2bnhA:
undetectable		 1dmyA-2bnhA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 SER A 302
GLY A 295
ASN A 289
LEU A 313
LEU A 303
 None
 1.29A 1lhuA-2bnhA:
undetectable		 1lhuA-2bnhA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 SER A 416
GLY A 409
ASN A 403
LEU A 427
LEU A 417
 None
 1.30A 1lhuA-2bnhA:
undetectable		 1lhuA-2bnhA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 11 LEU A  72
LEU A  92
LEU A 120
LEU A  85
LEU A  87
 None
 1.00A 1mx1B-2bnhA:
undetectable		 1mx1B-2bnhA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 11 VAL A 274
LEU A 258
LEU A 271
LEU A 214
LEU A 229
 None
 1.28A 1mx1B-2bnhA:
undetectable		 1mx1B-2bnhA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 5 VAL A 328
CYH A 325
ALA A 322
CYH A 324
 None
 1.17A 1mz9D-2bnhA:
undetectable		 1mz9D-2bnhA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 VAL A 315
LEU A 271
GLY A 295
ALA A 296
LEU A 313
 None
 0.82A 1r9oA-2bnhA:
undetectable		 1r9oA-2bnhA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 4 GLY A 245
SER A 251
VAL A 274
LEU A 242
 None
 0.93A 1yajB-2bnhA:
undetectable		 1yajB-2bnhA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 LEU A 338
CYH A 308
VAL A 328
LEU A 320
LEU A 372
 None
 1.39A 2hc4A-2bnhA:
undetectable		 2hc4A-2bnhA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 LEU A 320
LEU A 343
ASN A 346
LEU A 372
LEU A 313
 None
 1.41A 2w8yB-2bnhA:
undetectable		 2w8yB-2bnhA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 CYH A 357
GLN A 358
SER A 361
LEU A 389
LEU A 372
 None
 1.46A 3adxA-2bnhA:
undetectable		 3adxA-2bnhA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 5 LEU A 201
GLY A 230
GLU A 145
CYH A 204
 None
 1.02A 3aiaA-2bnhA:
undetectable
3aiaB-2bnhA:
undetectable		 3aiaA-2bnhA:
19.90
3aiaB-2bnhA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 LEU A 395
LEU A 389
ASN A 392
LEU A 390
LEU A 400
 None
 1.32A 3d90B-2bnhA:
undetectable		 3d90B-2bnhA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 ALA A 359
GLN A 358
LEU A 360
CYH A 300
LEU A 304
 None
 1.03A 3dzyA-2bnhA:
undetectable		 3dzyA-2bnhA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 11 ASN A 346
LEU A 372
ALA A 359
VAL A 328
LEU A 303
 None
 1.37A 3jwqB-2bnhA:
undetectable
3jwqC-2bnhA:
undetectable		 3jwqB-2bnhA:
21.89
3jwqC-2bnhA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		3 / 3 GLU A 130
LEU A 133
ASP A 134
 None
 0.27A 3ko0A-2bnhA:
undetectable		 3ko0A-2bnhA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		3 / 3 GLU A 130
LEU A 133
ASP A 134
 None
 0.26A 3ko0T-2bnhA:
undetectable		 3ko0T-2bnhA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		3 / 3 GLU A 294
LEU A 298
LEU A 330
 None
 0.62A 3ohtA-2bnhA:
undetectable		 3ohtA-2bnhA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		3 / 3 GLU A 294
LEU A 298
LEU A 330
 None
 0.62A 3ohtB-2bnhA:
undetectable		 3ohtB-2bnhA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 8 GLY A 295
ASP A 293
GLY A 292
VAL A 315
 None
 0.86A 4c5nC-2bnhA:
2.0		 4c5nC-2bnhA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		6 / 12 ASN A 175
LEU A 157
GLY A 205
ASN A 232
LEU A 149
ASN A 210
 None
 1.48A 4dc3B-2bnhA:
undetectable		 4dc3B-2bnhA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		6 / 12 CYH A 382
GLY A 349
GLY A 352
ASN A 379
GLY A 409
LEU A 413
 None
 1.43A 4fp9A-2bnhA:
undetectable		 4fp9A-2bnhA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		6 / 12 CYH A 382
GLY A 349
GLY A 352
ASN A 379
GLY A 409
LEU A 413
 None
 1.40A 4fp9D-2bnhA:
undetectable		 4fp9D-2bnhA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		6 / 12 CYH A 382
GLY A 349
GLY A 352
ASN A 379
GLY A 409
LEU A 413
 None
 1.40A 4fp9F-2bnhA:
undetectable		 4fp9F-2bnhA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 7 LEU A 370
LEU A 395
SER A 394
THR A 365
 None
 1.03A 4ikjA-2bnhA:
undetectable
4ikjB-2bnhA:
undetectable		 4ikjA-2bnhA:
13.36
4ikjB-2bnhA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 LEU A  58
LEU A  63
ILE A  43
GLY A  34
LEU A  30
 None
 1.00A 4lmnA-2bnhA:
undetectable		 4lmnA-2bnhA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		3 / 3 ASP A  31
VAL A  27
ASN A  61
 None
 0.78A 4lmnA-2bnhA:
undetectable		 4lmnA-2bnhA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 5 CYH A 300
LEU A 338
LEU A 370
LEU A 313
 None
 1.21A 4n09D-2bnhA:
undetectable		 4n09D-2bnhA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 7 LEU A  92
ASN A 118
LEU A 142
LEU A  85
 None
 1.03A 4okwA-2bnhA:
undetectable		 4okwA-2bnhA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 10 CYH A  97
LEU A  92
LEU A 115
LEU A 104
LEU A  72
 None
 1.23A 4p65A-2bnhA:
undetectable
4p65B-2bnhA:
undetectable
4p65F-2bnhA:
undetectable
4p65H-2bnhA:
undetectable		 4p65A-2bnhA:
8.42
4p65B-2bnhA:
6.59
4p65F-2bnhA:
6.59
4p65H-2bnhA:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 LEU A  92
GLY A 121
CYH A 147
ASN A 175
ALA A 123
 None
 1.40A 4pclB-2bnhA:
undetectable		 4pclB-2bnhA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RGC_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 ILE A 177
ALA A 152
ASP A 122
LEU A 125
LEU A 170
 None
 1.14A 4rgcA-2bnhA:
undetectable		 4rgcA-2bnhA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 5 LEU A 400
ASP A 399
LEU A 413
THR A 432
 None
 1.08A 4wozF-2bnhA:
undetectable
4wozH-2bnhA:
undetectable		 4wozF-2bnhA:
20.13
4wozH-2bnhA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 12 CYH A 243
ILE A 263
LEU A 275
LEU A 281
LEU A 256
 None
 1.32A 4xumA-2bnhA:
undetectable		 4xumA-2bnhA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 10 LEU A 398
LEU A 413
SER A 380
ASN A 403
LEU A 429
 None
 1.18A 4yiaA-2bnhA:
undetectable		 4yiaA-2bnhA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 8 LEU A 185
GLY A 181
VAL A 184
ALA A 158
LEU A 161
 None
 1.14A 4zauA-2bnhA:
undetectable		 4zauA-2bnhA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 11 LEU A 185
LEU A 115
LEU A 139
LEU A 167
LEU A 113
 None
 1.03A 4zowA-2bnhA:
undetectable		 4zowA-2bnhA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 11 LEU A 332
LEU A 286
LEU A 310
LEU A 338
LEU A 284
 None
 1.04A 4zowA-2bnhA:
undetectable		 4zowA-2bnhA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 7 ILE A 353
CYH A 375
LYS A 347
LEU A 348
GLY A 352
 None
 1.32A 5a06A-2bnhA:
undetectable		 5a06A-2bnhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 7 ILE A 353
CYH A 375
LYS A 347
LEU A 348
GLY A 352
 None
 1.29A 5a06C-2bnhA:
undetectable		 5a06C-2bnhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 7 ILE A 353
CYH A 375
LYS A 347
LEU A 348
GLY A 352
 None
 1.30A 5a06E-2bnhA:
undetectable		 5a06E-2bnhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 7 ILE A 353
CYH A 375
LYS A 347
LEU A 348
GLY A 352
 None
 1.29A 5a06F-2bnhA:
3.1		 5a06F-2bnhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		4 / 7 VAL A 315
LEU A 320
LEU A 341
LEU A 338
 None
 0.66A 5jq7A-2bnhA:
undetectable		 5jq7A-2bnhA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6M_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		5 / 11 ILE A 177
ALA A 152
ASP A 122
LEU A 125
LEU A 170
 None
 1.06A 5z6mA-2bnhA:
undetectable		 5z6mA-2bnhA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 2bnh RIBONUCLEASE
INHIBITOR
(Sus
scrofa) 		3 / 3 ILE A 177
ASN A 232
CYH A 211
 None
 0.75A 6bp4A-2bnhA:
undetectable		 6bp4A-2bnhA:
21.20