SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bo9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		5 / 12 VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
 None
 1.33A 2vdyA-2bo9B:
undetectable		 2vdyA-2bo9B:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		4 / 4 GLU B  60
GLY B  96
THR B  95
GLU B  94
 None
 0.98A 3e9xA-2bo9B:
undetectable		 3e9xA-2bo9B:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		4 / 7 VAL B  74
VAL B  37
PHE B  56
ILE B  21
 None
 0.89A 3zjqA-2bo9B:
undetectable		 3zjqA-2bo9B:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		4 / 7 VAL B  74
VAL B  37
PHE B  56
ILE B  21
 None
 0.89A 3zjqB-2bo9B:
undetectable		 3zjqB-2bo9B:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		5 / 12 VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
 None
 1.23A 4c49A-2bo9B:
undetectable		 4c49A-2bo9B:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		5 / 12 VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
 None
 1.38A 4c49B-2bo9B:
undetectable		 4c49B-2bo9B:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		5 / 12 VAL B  58
PHE B  89
ILE B  21
ASN B  22
PHE B  91
 None
 1.35A 4c49C-2bo9B:
undetectable		 4c49C-2bo9B:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		4 / 5 PRO B  99
ASP B 103
ILE B  62
VAL B 142
 None
None
MPD  B 303 ( 4.8A)
None
 1.35A 4hytA-2bo9B:
undetectable		 4hytA-2bo9B:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2bo9 HUMAN LATEXIN
(Homo
sapiens) 		3 / 3 GLN B 150
ILE B 187
HIS B 185
 None
 0.64A 5z12B-2bo9B:
undetectable		 5z12B-2bo9B:
19.44