SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		3 / 3 PRO A 199
ASP A 102
ASP A  49
 None
 0.75A 1sqfA-2bolA:
undetectable		 1sqfA-2bolA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		5 / 12 ALA A 204
GLY A 202
LEU A 203
ARG A  41
VAL A  35
 None
 1.33A 1vpoH-2bolA:
undetectable
1vpoL-2bolA:
2.4		 1vpoH-2bolA:
20.95
1vpoL-2bolA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		4 / 6 LEU A 137
SER A 159
ILE A 183
PHE A 123
 None
 1.03A 3ko0S-2bolA:
undetectable		 3ko0S-2bolA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		5 / 12 LEU A 162
PHE A 114
VAL A 116
MET A  66
PHE A  58
 None
 1.47A 3nuvA-2bolA:
undetectable		 3nuvA-2bolA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		3 / 3 LYS A 251
PRO A 207
LYS A 196
 None
 1.46A 4dr5L-2bolA:
0.0		 4dr5L-2bolA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		3 / 3 LYS A 251
PRO A 207
LYS A 196
 None
 1.47A 4dr6L-2bolA:
0.0		 4dr6L-2bolA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		3 / 3 LYS A 251
PRO A 207
LYS A 196
 None
 1.44A 4duzL-2bolA:
0.0		 4duzL-2bolA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		3 / 3 PHE A  70
VAL A  73
GLU A  96
 None
 0.80A 4fvqA-2bolA:
undetectable		 4fvqA-2bolA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		5 / 11 ASN A 119
LEU A 181
VAL A 116
ILE A 183
LEU A 162
 None
 1.44A 4k37B-2bolA:
undetectable		 4k37B-2bolA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		4 / 8 PRO A 163
SER A 165
VAL A 166
GLY A 256
 None
 0.86A 4mk4A-2bolA:
undetectable		 4mk4A-2bolA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		4 / 5 GLY A 110
ASP A 109
GLU A 105
VAL A 182
 None
 0.98A 4nkvD-2bolA:
undetectable		 4nkvD-2bolA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		4 / 5 HIS A 236
VAL A 308
GLU A 309
LYS A 218
 None
 1.41A 4p6vB-2bolA:
undetectable
4p6vE-2bolA:
undetectable		 4p6vB-2bolA:
19.50
4p6vE-2bolA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 2bol SMALL HEAT SHOCK
PROTEIN
(Taenia
saginata) 		4 / 7 LEU A  97
VAL A 166
TYR A 104
SER A 165
 None
 0.88A 5umwA-2bolA:
undetectable
5umwF-2bolA:
undetectable		 5umwA-2bolA:
14.06
5umwF-2bolA:
14.06