SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
RAS-RELATED PROTEIN
RAL-A
(Clostridium
botulinum;
Homo
sapiens) 		3 / 3 ARG A 135
THR B1080
VAL B1077
 None
 0.96A 1hxbA-2bovA:
undetectable		 1hxbA-2bovA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_A_ACTA601_0
(VANILLYL-ALCOHOL
OXIDASE)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 5 TYR B1134
ILE B1239
TYR B1223
ARG B1167
 None
 1.47A 1qltA-2bovB:
0.1		 1qltA-2bovB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QLT_B_ACTB601_0
(VANILLYL-ALCOHOL
OXIDASE)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 5 TYR B1134
ILE B1239
TYR B1223
ARG B1167
 None
 1.48A 1qltB-2bovB:
0.1		 1qltB-2bovB:
19.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 7 ARG B1128
SER B1174
ARG B1186
GLU B1214
 None
 0.98A 2c8aA-2bovB:
34.7		 2c8aA-2bovB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		5 / 7 ARG B1128
GLY B1129
SER B1174
ARG B1186
GLU B1214
 None
 0.92A 2c8aB-2bovB:
33.0		 2c8aB-2bovB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 6 ARG B1128
SER B1174
ARG B1186
GLU B1214
 None
 0.98A 2c8aC-2bovB:
34.3		 2c8aC-2bovB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		5 / 7 ARG B1128
GLY B1129
SER B1174
ARG B1186
GLU B1214
 None
 0.93A 2c8aD-2bovB:
32.7		 2c8aD-2bovB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
RAS-RELATED PROTEIN
RAL-A
(Clostridium
botulinum;
Homo
sapiens) 		3 / 3 ARG A 135
THR B1080
VAL B1077
 None
 0.85A 2q64A-2bovA:
undetectable		 2q64A-2bovA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
RAS-RELATED PROTEIN
RAL-A
(Clostridium
botulinum;
Homo
sapiens) 		3 / 3 ARG A 135
THR B1080
VAL B1077
 None
 0.76A 2qakA-2bovA:
undetectable		 2qakA-2bovA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 5 ALA A 177
GLY A  88
LYS A  16
HIS A  15
 None
 1.36A 2ylgA-2bovA:
undetectable		 2ylgA-2bovA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 6 MET A 172
ARG A  52
PRO A 121
GLY A  86
 None
 1.46A 3aqiA-2bovA:
3.9		 3aqiA-2bovA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 6 MET A 172
ARG A  52
PRO A 121
GLY A  86
 None
 1.48A 3aqiB-2bovA:
0.3		 3aqiB-2bovA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 6 ARG A 113
PHE A  83
ASP A  74
TYR A  82
 None
 1.46A 3jqaA-2bovA:
4.0		 3jqaA-2bovA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 6 ARG A 113
PHE A  83
ASP A  74
TYR A  82
 None
 1.46A 3jqaB-2bovA:
3.9		 3jqaB-2bovA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 6 ARG A 113
PHE A  83
ASP A  74
TYR A  82
 None
 1.48A 3jqaC-2bovA:
4.0		 3jqaC-2bovA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 6 ARG A 113
PHE A  83
ASP A  74
TYR A  82
 None
 1.49A 3jqaD-2bovA:
4.0		 3jqaD-2bovA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		5 / 9 VAL A  92
GLY A 126
GLN A  72
ASN A 127
GLY A  26
 None
None
None
GDP  A1184 (-3.3A)
GDP  A1184 (-3.2A)
 1.38A 3kmoA-2bovA:
undetectable		 3kmoA-2bovA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 5 ILE B1086
GLN B1107
ILE B1076
TYR B1079
 None
 1.27A 4a99D-2bovB:
undetectable		 4a99D-2bovB:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		4 / 5 PRO B1187
GLY B1185
ASP B1227
ASP B1233
 None
 0.99A 4n48B-2bovB:
undetectable		 4n48B-2bovB:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		3 / 3 ILE B1188
PRO B1187
ILE B1237
 None
 0.45A 5hw8F-2bovB:
undetectable		 5hw8F-2bovB:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 2bov RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 5 ALA A 177
GLY A  88
LYS A  16
HIS A  15
 None
 1.36A 5jliA-2bovA:
undetectable		 5jliA-2bovA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
RAS-RELATED PROTEIN
RAL-A
(Clostridium
botulinum;
Homo
sapiens) 		4 / 7 GLU A 147
ALA B1057
GLY B1059
TYR B1063
 None
 1.04A 5uxdA-2bovA:
undetectable		 5uxdA-2bovA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3
(Clostridium
botulinum) 		3 / 3 PHE B1183
ARG B1128
ALA B1210
 None
 0.86A 6ecfB-2bovB:
undetectable		 6ecfB-2bovB:
20.32