SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bp5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU M 172
TYR M 205
PHE M 174
 None
 0.78A 1eqbB-2bp5M:
undetectable		 1eqbB-2bp5M:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU M 172
TYR M 205
PHE M 174
 None
 0.78A 1eqbA-2bp5M:
undetectable		 1eqbA-2bp5M:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU M 172
TYR M 205
PHE M 174
 None
 0.78A 1eqbD-2bp5M:
undetectable		 1eqbD-2bp5M:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLU M 172
TYR M 205
PHE M 174
 None
 0.78A 1eqbC-2bp5M:
undetectable		 1eqbC-2bp5M:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 8 ALA M 194
GLY M 429
PRO M 396
ILE M 284
ILE M 283
 None
 1.21A 1hshD-2bp5M:
undetectable		 1hshD-2bp5M:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		6 / 12 LEU M 206
ILE M 263
ILE M 243
MET M 216
PHE M 214
VAL M 177
 None
 1.46A 2ygnA-2bp5M:
undetectable		 2ygnA-2bp5M:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 11 ALA M 317
LEU M 316
PHE M 394
GLY M 360
SER M 309
 None
 1.19A 3bpxA-2bp5M:
undetectable
3bpxB-2bp5M:
undetectable		 3bpxA-2bp5M:
15.40
3bpxB-2bp5M:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 10 ILE M 263
PHE M 265
VAL M 401
MET M 202
LEU M 404
 None
 1.37A 3eqmA-2bp5M:
undetectable		 3eqmA-2bp5M:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 11 ARG M 323
GLN M 318
PRO M 393
PRO M 286
ILE M 307
 None
 1.46A 3ganA-2bp5M:
undetectable		 3ganA-2bp5M:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 11 ARG M 323
VAL M 392
PRO M 393
PRO M 286
ILE M 307
 None
 1.23A 3ganA-2bp5M:
undetectable		 3ganA-2bp5M:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 GLY M 332
PRO M 327
LEU M 372
 None
 0.53A 3hcpB-2bp5M:
undetectable		 3hcpB-2bp5M:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		4 / 8 ILE M 366
ALA M 350
THR M 326
VAL M 335
 None
 0.84A 3me6B-2bp5M:
undetectable		 3me6B-2bp5M:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 12 CYH M 337
ILE M 355
SER M 364
ILE M 324
ALA M 350
 None
 1.23A 3vw1D-2bp5M:
undetectable		 3vw1D-2bp5M:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 LYS M 312
PRO M 313
SER M 314
 None
 0.43A 4k50I-2bp5M:
undetectable		 4k50I-2bp5M:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		6 / 12 LYS M 354
VAL M 322
ILE M 324
ALA M 350
VAL M 305
ILE M 307
 None
 1.27A 5j2tC-2bp5M:
undetectable		 5j2tC-2bp5M:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 11 ILE M 263
PHE M 265
VAL M 401
MET M 202
LEU M 404
 None
 1.31A 5jkwA-2bp5M:
undetectable		 5jkwA-2bp5M:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 10 ILE M 263
PHE M 265
VAL M 401
MET M 202
LEU M 404
 None
 1.32A 5jl7A-2bp5M:
0.0		 5jl7A-2bp5M:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		4 / 6 ASN M 182
PRO M 396
VAL M 196
TYR M 431
 None
 1.10A 5umd2-2bp5M:
undetectable
5umdF-2bp5M:
undetectable		 5umd2-2bp5M:
11.78
5umdF-2bp5M:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		5 / 12 ALA M 395
GLY M 426
GLU M 391
LEU M 178
PHE M 390
 None
 1.46A 5vlmF-2bp5M:
undetectable		 5vlmF-2bp5M:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50
(Rattus
norvegicus) 		3 / 3 ARG M 162
PHE M 407
LEU M 206
 None
 0.49A 5x1bC-2bp5M:
undetectable		 5x1bC-2bp5M:
19.26