SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bqp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
5 / 12 GLY A 102
GLY A  97
TYR A 100
ILE A 144
THR A 112
None
1.12A 1p91B-2bqpA:
undetectable
1p91B-2bqpA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
6 / 10 ILE A  71
ALA A 213
PHE A  67
PHE A  69
ILE A 137
LEU A 177
None
1.49A 2w3aB-2bqpA:
undetectable
2w3aB-2bqpA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
5 / 12 ALA A 221
THR A  40
ARG A 135
GLY A  82
LEU A 154
None
1.36A 3aodC-2bqpA:
undetectable
3aodC-2bqpA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
4 / 6 HIS A 136
VAL A 175
ILE A 144
LEU A 173
MN  A 236 (-3.7A)
None
None
None
0.88A 3kk6A-2bqpA:
undetectable
3kk6A-2bqpA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
5 / 12 THR A  92
ILE A  52
ILE A  87
VAL A 203
PRO A 204
None
1.03A 3kpdC-2bqpA:
undetectable
3kpdC-2bqpA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
4 / 4 SER A 226
SER A  66
THR A  65
SER A 228
None
1.15A 3loqA-2bqpA:
0.0
3loqA-2bqpA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
5 / 9 ALA A 165
ILE A  52
LEU A 199
ILE A  87
ILE A 209
None
0.87A 5nunA-2bqpA:
undetectable
5nunA-2bqpA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)
2bqp PROTEIN (PEA LECTIN)
(Pisum
sativum)
4 / 5 LEU A 101
THR A 214
THR A  96
GLY A  98
None
None
None
GLC  A 337 ( 3.8A)
1.21A 6gtqA-2bqpA:
undetectable
6gtqA-2bqpA:
21.31