SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2btj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
4 / 4 ASP A  55
LEU A 162
LEU A 137
LEU A 161
None
1.20A 1u18A-2btjA:
undetectable
1u18A-2btjA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
5 / 12 GLU A 212
ARG A  66
MET A  14
GLY A  27
LEU A  42
IEY  A  64 ( 3.6A)
IEY  A  64 ( 3.0A)
NFA  A  61 ( 3.7A)
None
NFA  A  61 ( 4.3A)
1.05A 2jfaB-2btjA:
undetectable
2jfaB-2btjA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
5 / 9 ALA A 103
VAL A 118
GLY A  16
ILE A  56
ALA A  60
None
None
None
None
NFA  A  61 ( 3.4A)
0.96A 2z0yB-2btjA:
undetectable
2z0yB-2btjA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
6 / 12 SER A  92
PHE A 173
GLY A 155
THR A 154
THR A 176
GLU A 144
None
1.31A 2zifA-2btjA:
undetectable
2zifA-2btjA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
3 / 3 HIS A 213
GLU A 212
HIS A 194
None
IEY  A  64 ( 3.6A)
IEY  A  64 ( 3.6A)
0.82A 3ba0A-2btjA:
undetectable
3ba0A-2btjA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
4 / 5 GLU A 181
GLY A 183
TYR A  78
GLN A  76
None
1.25A 3w9tE-2btjA:
undetectable
3w9tE-2btjA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
4 / 5 GLU A 181
GLY A 183
TYR A  78
GLN A  76
None
1.29A 3w9tG-2btjA:
undetectable
3w9tG-2btjA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
4 / 6 PHE A  95
TYR A 169
LEU A 161
THR A  59
None
None
None
IEY  A  64 ( 4.2A)
1.26A 4paeA-2btjA:
undetectable
4paeA-2btjA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
3 / 3 SER A 218
ALA A 216
VAL A 215
None
0.58A 4x20C-2btjA:
undetectable
4x20C-2btjA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
5 / 10 TYR A 177
ARG A  91
VAL A  67
TYR A  71
ILE A 196
None
IEY  A  64 ( 2.9A)
None
None
IEY  A  64 ( 3.7A)
1.31A 5hw8C-2btjA:
undetectable
5hw8H-2btjA:
undetectable
5hw8C-2btjA:
22.22
5hw8H-2btjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UH6_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
5 / 12 GLN A  38
LEU A 210
ASP A  26
ASN A 105
ARG A  13
IEY  A  64 ( 3.6A)
IEY  A  64 ( 3.7A)
None
IEY  A  64 ( 4.3A)
None
1.36A 5uh6C-2btjA:
1.3
5uh6C-2btjA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
5 / 12 THR A  58
MET A 159
PHE A 173
ILE A 157
THR A 175
None
IEY  A  64 ( 3.5A)
None
IEY  A  64 ( 4.8A)
None
1.22A 5w8aA-2btjA:
undetectable
5w8aA-2btjA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
4 / 6 PHE A 125
PRO A 126
GLY A 129
ASN A 128
None
0.84A 5x24A-2btjA:
undetectable
5x24A-2btjA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
5 / 12 TRP A  89
LEU A  93
HIS A 194
THR A  58
LEU A  57
IEY  A  64 ( 4.0A)
None
IEY  A  64 ( 3.6A)
None
NFA  A  61 ( 4.4A)
1.18A 6djzB-2btjA:
undetectable
6djzB-2btjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
2btj GREEN TO RED
PHOTOCONVERTIBLE
GPF-LIKE PROTEIN
EOSFP

(Lobophyllia
hemprichii)
4 / 5 ARG A  91
ARG A 174
GLY A 155
ASP A 156
IEY  A  64 ( 2.9A)
None
None
None
1.22A 6dwjB-2btjA:
undetectable
6dwjD-2btjA:
undetectable
6dwjB-2btjA:
16.67
6dwjD-2btjA:
16.67