SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2btw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 4 HIS A 143
VAL A 141
THR A 124
LEU A 131
 None
 1.42A 1oq5A-2btwA:
undetectable		 1oq5A-2btwA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A  71
TYR A 135
LEU A  79
VAL A 237
ILE A 168
 None
 1.28A 3g9eA-2btwA:
undetectable		 3g9eA-2btwA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 ARG A 153
ASN A 148
TRP A 218
GLU A 150
 None
 1.46A 3galA-2btwA:
undetectable		 3galA-2btwA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 ARG A 153
ASN A 148
TRP A 218
GLU A 150
 None
 1.44A 3galB-2btwA:
undetectable		 3galB-2btwA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 THR A 109
TYR A 135
ILE A  75
SER A 105
 None
 1.30A 3peoG-2btwA:
undetectable		 3peoG-2btwA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 139
SER A 238
ASN A 165
ASN A 159
GLN A 155
 None
 1.46A 4kukA-2btwA:
undetectable		 4kukA-2btwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 VAL A 139
SER A 238
ASN A 165
ASN A 159
GLN A 155
 None
 1.46A 4kuoA-2btwA:
undetectable		 4kuoA-2btwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 GLU A  88
THR A  89
THR A 109
ASN A  85
 None
 1.25A 4pfjB-2btwA:
undetectable		 4pfjB-2btwA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 8 ILE A 149
VAL A 139
ILE A 168
ILE A 132
ILE A 184
 None
 1.17A 5hi2A-2btwA:
undetectable		 5hi2A-2btwA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 THR A  89
THR A 109
LEU A  79
 None
 0.63A 5m66D-2btwA:
undetectable		 5m66D-2btwA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 PHE A 236
GLN A 155
MET A 221
THR A 147
 None
 1.09A 5u6mA-2btwA:
undetectable		 5u6mA-2btwA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 PHE A 236
GLN A 155
MET A 221
THR A 147
 None
 1.22A 5u6mB-2btwA:
undetectable		 5u6mB-2btwA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 8 PHE A 236
GLN A 155
MET A 221
THR A 147
 None
 1.20A 5u6nA-2btwA:
undetectable		 5u6nA-2btwA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 PHE A 236
GLN A 155
MET A 221
THR A 147
 None
 1.26A 5u6nB-2btwA:
undetectable		 5u6nB-2btwA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 2btw ALR0975 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A  68
ARG A 173
ILE A 199
ILE A 176
GLN A 178
 None
 1.28A 5y80A-2btwA:
undetectable		 5y80A-2btwA:
15.64