SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2buc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 HIS A 748
TRP A 627
ALA A 654
TRP A 629
 None
 1.34A 1dy4A-2bucA:
undetectable		 1dy4A-2bucA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 PHE A 647
THR A 636
VAL A 635
ALA A 642
 None
 1.00A 1fo4B-2bucA:
undetectable		 1fo4B-2bucA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 ALA A 226
VAL A 198
TRP A 154
 None
 1.03A 1gmkA-2bucA:
undetectable
1gmkB-2bucA:
undetectable		 1gmkA-2bucA:
2.76
1gmkB-2bucA:
2.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 ARG A 184
VAL A 167
TRP A 168
 None
 1.26A 1qwcA-2bucA:
1.4		 1qwcA-2bucA:
20.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		12 / 12 ARG A 125
GLU A 205
GLU A 206
SER A 209
PHE A 357
TYR A 547
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 (-3.4A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.33A 1x70A-2bucA:
56.4		 1x70A-2bucA:
88.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 ARG A 358
SER A 630
TYR A 631
 008  A1767 ( 4.0A)
SO4  A1769 ( 3.0A)
None
 0.68A 1x70A-2bucA:
56.4		 1x70A-2bucA:
88.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		12 / 12 ARG A 125
GLU A 205
GLU A 206
SER A 209
ARG A 358
SER A 630
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 (-3.4A)
008  A1767 ( 4.0A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.61A 1x70B-2bucA:
56.0		 1x70B-2bucA:
88.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 PHE A 357
TYR A 547
TYR A 631
 008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
None
 0.25A 1x70B-2bucA:
56.0		 1x70B-2bucA:
88.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 TRP A 201
GLN A 320
TYR A 299
TYR A 256
 None
 1.30A 2ph9A-2bucA:
undetectable
2ph9B-2bucA:
undetectable		 2ph9A-2bucA:
15.28
2ph9B-2bucA:
15.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 GLU A 205
GLU A 206
PHE A 357
TRP A 629
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
VAL A 711
HIS A 740
 008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 (-3.5A)
None
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
None
SO4  A1769 ( 4.1A)
 0.55A 2rguA-2bucA:
55.8		 2rguA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		9 / 12 GLU A 205
GLU A 206
PHE A 357
TYR A 547
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
 008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
 0.74A 2rguA-2bucA:
55.8		 2rguA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
PHE A 357
SER A 630
VAL A 656
VAL A 711
 008  A1767 (-3.9A)
008  A1767 (-3.5A)
SO4  A1769 ( 3.0A)
None
None
 1.38A 2rguA-2bucA:
55.8		 2rguA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
PHE A 357
TYR A 547
SER A 630
VAL A 656
 008  A1767 (-3.9A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
 1.39A 2rguA-2bucA:
55.8		 2rguA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TRP A 629
TYR A 634
TYR A 662
VAL A 711
HIS A 740
 None
None
008  A1767 (-4.4A)
None
SO4  A1769 ( 4.1A)
 1.09A 2rguA-2bucA:
55.8		 2rguA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		10 / 11 GLU A 205
GLU A 206
TRP A 629
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
VAL A 711
HIS A 740
 008  A1767 (-3.9A)
008  A1767 (-2.5A)
None
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
None
SO4  A1769 ( 4.1A)
 0.56A 2rguB-2bucA:
55.7		 2rguB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		7 / 11 GLU A 205
GLU A 206
TYR A 547
TYR A 631
VAL A 656
TYR A 662
TYR A 666
 008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
 0.62A 2rguB-2bucA:
55.7		 2rguB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 11 GLU A 205
TYR A 547
TYR A 631
VAL A 656
TYR A 662
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
None
None
008  A1767 (-4.4A)
 1.27A 2rguB-2bucA:
55.7		 2rguB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 11 TRP A 629
TYR A 634
TYR A 662
VAL A 711
HIS A 740
 None
None
008  A1767 (-4.4A)
None
SO4  A1769 ( 4.1A)
 1.07A 2rguB-2bucA:
55.7		 2rguB-2bucA:
88.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 ARG A 433
GLU A 448
SER A 486
 None
 0.87A 2xkkA-2bucA:
1.9
2xkkC-2bucA:
2.6		 2xkkA-2bucA:
20.45
2xkkC-2bucA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 SER A 349
PRO A 359
GLY A 355
TRP A 353
 None
 1.32A 2y7kB-2bucA:
0.0		 2y7kB-2bucA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 6 SER A 349
PRO A 359
GLY A 355
TRP A 353
 None
 1.20A 2y7pA-2bucA:
undetectable		 2y7pA-2bucA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 GLY A 335
ASP A 329
TYR A 330
ARG A 310
 None
 1.07A 3arrA-2bucA:
undetectable		 3arrA-2bucA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 GLY A 335
ASP A 329
TYR A 330
ARG A 310
 None
 1.09A 3aruA-2bucA:
undetectable		 3aruA-2bucA:
21.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
SER A 630
TYR A 631
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.66A 3bjmA-2bucA:
55.9		 3bjmA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.37A 3bjmA-2bucA:
55.9		 3bjmA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		6 / 12 GLU A 205
TYR A 547
TYR A 631
VAL A 656
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
None
None
008  A1767 (-4.4A)
None
 1.16A 3bjmA-2bucA:
55.9		 3bjmA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.00A 3bjmA-2bucA:
55.9		 3bjmA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
PHE A 357
TYR A 547
SER A 630
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.72A 3bjmB-2bucA:
56.3		 3bjmB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
PHE A 357
TYR A 547
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.42A 3bjmB-2bucA:
56.3		 3bjmB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
PHE A 357
TYR A 547
VAL A 656
TYR A 662
 008  A1767 (-3.9A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
None
008  A1767 (-4.4A)
 1.42A 3bjmB-2bucA:
56.3		 3bjmB-2bucA:
88.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 TYR A 670
GLU A 205
ASP A 739
 None
008  A1767 (-3.9A)
None
 0.72A 3bxoA-2bucA:
undetectable		 3bxoA-2bucA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 TYR A 670
GLU A 205
ASP A 739
 None
008  A1767 (-3.9A)
None
 0.75A 3bxoB-2bucA:
3.7		 3bxoB-2bucA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 TYR A  70
TYR A 105
ILE A  76
 None
 0.83A 3eteA-2bucA:
undetectable
3eteB-2bucA:
undetectable		 3eteA-2bucA:
22.35
3eteB-2bucA:
22.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.32A 3g0bA-2bucA:
53.2		 3g0bA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
SO4  A1769 ( 4.1A)
 0.54A 3g0bA-2bucA:
53.2		 3g0bA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
SER A 630
VAL A 656
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
None
 1.21A 3g0bA-2bucA:
53.2		 3g0bA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
TYR A 547
SER A 630
VAL A 656
TYR A 662
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
 1.28A 3g0bA-2bucA:
53.2		 3g0bA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.03A 3g0bA-2bucA:
53.2		 3g0bA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.33A 3g0bB-2bucA:
52.8		 3g0bB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
SO4  A1769 ( 4.1A)
 0.55A 3g0bB-2bucA:
52.8		 3g0bB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
SER A 630
VAL A 656
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
None
 1.19A 3g0bB-2bucA:
52.8		 3g0bB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
TYR A 547
SER A 630
VAL A 656
TYR A 662
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
 1.26A 3g0bB-2bucA:
52.8		 3g0bB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.08A 3g0bB-2bucA:
52.8		 3g0bB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.31A 3g0bC-2bucA:
52.6		 3g0bC-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		9 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
 0.59A 3g0bC-2bucA:
52.6		 3g0bC-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
SER A 630
VAL A 656
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
None
 1.17A 3g0bC-2bucA:
52.6		 3g0bC-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.08A 3g0bC-2bucA:
52.6		 3g0bC-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.35A 3g0bD-2bucA:
55.3		 3g0bD-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
SO4  A1769 ( 4.1A)
 0.55A 3g0bD-2bucA:
55.3		 3g0bD-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
SER A 630
VAL A 656
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
None
 1.18A 3g0bD-2bucA:
55.3		 3g0bD-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
TYR A 547
SER A 630
VAL A 656
TYR A 662
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
 1.22A 3g0bD-2bucA:
55.3		 3g0bD-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.10A 3g0bD-2bucA:
55.3		 3g0bD-2bucA:
88.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 GLU A 309
GLU A 308
TRP A 337
 None
 1.31A 3hrdA-2bucA:
undetectable
3hrdE-2bucA:
undetectable
3hrdF-2bucA:
undetectable		 3hrdA-2bucA:
19.78
3hrdE-2bucA:
19.78
3hrdF-2bucA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 ARG A 358
GLU A 206
TYR A 670
 008  A1767 ( 4.0A)
008  A1767 (-2.5A)
None
 0.92A 3k37B-2bucA:
2.2		 3k37B-2bucA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 ASP A 329
LEU A 313
ILE A 311
PHE A 364
PHE A 371
 None
 1.23A 3ko0G-2bucA:
undetectable
3ko0H-2bucA:
undetectable
3ko0I-2bucA:
undetectable
3ko0J-2bucA:
undetectable		 3ko0G-2bucA:
7.57
3ko0H-2bucA:
7.57
3ko0I-2bucA:
7.57
3ko0J-2bucA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 VAL A 656
VAL A 688
TRP A 659
 None
 0.93A 3l8lC-2bucA:
undetectable
3l8lD-2bucA:
undetectable		 3l8lC-2bucA:
2.76
3l8lD-2bucA:
2.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 10 LEU A 445
ALA A 459
GLY A 406
ILE A 407
LEU A 431
 None
None
SO4  A1768 (-3.4A)
SO4  A1768 (-3.9A)
None
 1.30A 3ogpB-2bucA:
undetectable		 3ogpB-2bucA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 ILE A 703
TRP A 627
TRP A 563
THR A  46
 None
 1.36A 3topA-2bucA:
undetectable		 3topA-2bucA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 1.06A 3ut5B-2bucA:
2.9		 3ut5B-2bucA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 1.04A 3ut5D-2bucA:
3.1		 3ut5D-2bucA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 8 TRP A 315
VAL A 303
TRP A 215
PHE A 208
 None
 1.16A 3v35A-2bucA:
undetectable		 3v35A-2bucA:
18.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
SER A 630
TYR A 631
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.55A 3w2tA-2bucA:
55.3		 3w2tA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.25A 3w2tA-2bucA:
55.3		 3w2tA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
TYR A 547
SER A 630
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
008  A1767 (-4.4A)
None
 1.27A 3w2tA-2bucA:
55.3		 3w2tA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.04A 3w2tA-2bucA:
55.3		 3w2tA-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		12 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
SER A 630
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.50A 3w2tB-2bucA:
55.7		 3w2tB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		6 / 12 GLU A 205
TYR A 547
SER A 630
VAL A 656
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
None
 1.23A 3w2tB-2bucA:
55.7		 3w2tB-2bucA:
88.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.03A 3w2tB-2bucA:
55.7		 3w2tB-2bucA:
88.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 6 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.95A 3wg7N-2bucA:
0.0
3wg7W-2bucA:
undetectable		 3wg7N-2bucA:
19.97
3wg7W-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 6 HIS A 740
SER A 630
GLU A 545
ASP A 556
 SO4  A1769 ( 4.1A)
SO4  A1769 ( 3.0A)
None
None
 1.35A 4blvA-2bucA:
2.1		 4blvA-2bucA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		6 / 11 SER A 644
GLY A 643
ALA A 642
ILE A 607
ILE A 544
ILE A 626
 None
 1.18A 4dt8A-2bucA:
undetectable		 4dt8A-2bucA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 PHE A  95
ASN A  75
ILE A 114
PHE A 116
 None
NAG  A1092 (-3.1A)
None
None
 0.84A 4ejjA-2bucA:
undetectable		 4ejjA-2bucA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 PHE A  95
ASN A  75
ILE A 114
PHE A 116
 None
NAG  A1092 (-3.1A)
None
None
 0.88A 4ejjD-2bucA:
undetectable		 4ejjD-2bucA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 8 ASN A 710
ASP A 708
VAL A 656
HIS A 704
 008  A1767 (-3.0A)
None
None
None
 1.22A 4f5zA-2bucA:
12.7		 4f5zA-2bucA:
15.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
ARG A 358
TYR A 547
SER A 630
VAL A 656
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 ( 4.0A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.56A 4ffwA-2bucA:
52.0		 4ffwA-2bucA:
81.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 PHE A 357
TYR A 631
TYR A 666
 008  A1767 (-3.5A)
None
008  A1767 (-3.8A)
 0.25A 4ffwA-2bucA:
52.0		 4ffwA-2bucA:
81.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
PHE A 357
TYR A 547
SER A 630
VAL A 656
TYR A 662
TYR A 666
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
None
SO4  A1769 ( 4.1A)
 0.57A 4ffwB-2bucA:
51.3		 4ffwB-2bucA:
81.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
PHE A 357
TYR A 547
VAL A 656
TYR A 662
 008  A1767 (-3.9A)
008  A1767 (-3.5A)
SO4  A1769 ( 4.5A)
None
008  A1767 (-4.4A)
 1.30A 4ffwB-2bucA:
51.3		 4ffwB-2bucA:
81.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 ARG A 358
TYR A 631
ASN A 710
 008  A1767 ( 4.0A)
None
008  A1767 (-3.0A)
 0.80A 4ffwB-2bucA:
51.3		 4ffwB-2bucA:
81.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 TYR A 135
ILE A 134
ASN A 138
ILE A 143
 None
 1.06A 4jtpA-2bucA:
undetectable		 4jtpA-2bucA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 LYS A 760
LEU A 759
GLU A 571
LEU A 567
 None
 1.31A 4k4yA-2bucA:
undetectable		 4k4yA-2bucA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 4 LYS A 760
LEU A 759
GLU A 571
LEU A 567
 None
 1.34A 4k4yE-2bucA:
undetectable		 4k4yE-2bucA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 LYS A 760
LEU A 759
GLU A 571
LEU A 567
 None
 1.33A 4k4yI-2bucA:
undetectable		 4k4yI-2bucA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 10 VAL A 546
TYR A 547
GLY A 599
SER A 630
GLY A 633
 None
SO4  A1769 ( 4.5A)
NDG  A1685 (-4.6A)
SO4  A1769 ( 3.0A)
None
 0.96A 4mmdA-2bucA:
undetectable		 4mmdA-2bucA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 VAL A 546
TYR A 547
GLY A 599
SER A 630
GLY A 633
 None
SO4  A1769 ( 4.5A)
NDG  A1685 (-4.6A)
SO4  A1769 ( 3.0A)
None
 1.01A 4mmdB-2bucA:
undetectable		 4mmdB-2bucA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 1.11A 4o2bB-2bucA:
undetectable		 4o2bB-2bucA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 11 ALA A 609
GLU A 608
LEU A 519
ILE A 594
GLY A 582
 None
 1.23A 4pxmB-2bucA:
undetectable		 4pxmB-2bucA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 THR A 275
THR A 283
ASP A 272
TYR A 330
 None
 1.18A 4qwpB-2bucA:
0.0		 4qwpB-2bucA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ASN A 192
PRO A 255
TRP A 124
TYR A 211
 None
 1.46A 4v2yB-2bucA:
0.0		 4v2yB-2bucA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 8 ASN A 192
PRO A 255
TRP A 124
TYR A 211
 None
 1.47A 4v2zB-2bucA:
0.0		 4v2zB-2bucA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 8 ASN A 192
PRO A 255
TRP A 124
TYR A 211
 None
 1.48A 4v30B-2bucA:
0.0		 4v30B-2bucA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 0.90A 4x1iD-2bucA:
undetectable		 4x1iD-2bucA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 1.06A 4x1yB-2bucA:
undetectable		 4x1yB-2bucA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 0.90A 4x1yD-2bucA:
2.8		 4x1yD-2bucA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 11 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 0.90A 4x20D-2bucA:
undetectable		 4x20D-2bucA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ASN A 192
PRO A 255
TRP A 124
TYR A 211
 None
 1.45A 5amjB-2bucA:
undetectable		 5amjB-2bucA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.96A 5b1aA-2bucA:
undetectable
5b1aJ-2bucA:
undetectable		 5b1aA-2bucA:
19.97
5b1aJ-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.89A 5b1bN-2bucA:
undetectable
5b1bW-2bucA:
undetectable		 5b1bN-2bucA:
19.97
5b1bW-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.94A 5b3sA-2bucA:
undetectable
5b3sJ-2bucA:
undetectable		 5b3sA-2bucA:
19.97
5b3sJ-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		3 / 3 ARG A 184
VAL A 167
TRP A 168
 None
 1.17A 5fvoA-2bucA:
0.9		 5fvoA-2bucA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 8 TYR A 118
ASP A 133
ILE A 155
ILE A 143
 None
 0.84A 5hw8H-2bucA:
undetectable		 5hw8H-2bucA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 VAL A 303
ILE A 287
LEU A 313
GLY A 302
TYR A 285
 None
 1.07A 5ienA-2bucA:
undetectable		 5ienA-2bucA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 0.99A 5itzB-2bucA:
undetectable		 5itzB-2bucA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
 None
 1.06A 5mioB-2bucA:
undetectable		 5mioB-2bucA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 8 ILE A 374
VAL A 404
THR A 398
ILE A 397
 SO4  A1768 (-4.9A)
None
None
None
 0.86A 5mzrE-2bucA:
undetectable		 5mzrE-2bucA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ASN A 192
PRO A 255
TRP A 124
TYR A 211
 None
 1.45A 5oh1B-2bucA:
0.0		 5oh1B-2bucA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ASN A 192
PRO A 255
TRP A 124
TYR A 211
 None
 1.44A 5oh3B-2bucA:
undetectable		 5oh3B-2bucA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 ILE A 703
ALA A 652
THR A 636
ILE A 626
ALA A 625
 None
 0.92A 5vceA-2bucA:
undetectable		 5vceA-2bucA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 5 GLY A 521
THR A 522
ASN A 518
LYS A 523
 None
 0.99A 5x23A-2bucA:
undetectable		 5x23A-2bucA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.86A 5xdqA-2bucA:
0.0
5xdqJ-2bucA:
undetectable		 5xdqA-2bucA:
19.97
5xdqJ-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 6 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.99A 5z86N-2bucA:
0.0
5z86W-2bucA:
undetectable		 5z86N-2bucA:
19.97
5z86W-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 6 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 1.00A 5zcoN-2bucA:
undetectable
5zcoW-2bucA:
undetectable		 5zcoN-2bucA:
19.97
5zcoW-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.96A 5zcpA-2bucA:
undetectable
5zcpJ-2bucA:
undetectable		 5zcpA-2bucA:
19.97
5zcpJ-2bucA:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 7 ILE A 384
ARG A 433
THR A 411
LEU A 410
 None
 0.97A 5zcqA-2bucA:
undetectable
5zcqJ-2bucA:
undetectable		 5zcqA-2bucA:
19.97
5zcqJ-2bucA:
7.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
SER A 630
TYR A 631
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.56A 6b1eB-2bucA:
56.1		 6b1eB-2bucA:
88.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		11 / 12 ARG A 125
GLU A 205
GLU A 206
TYR A 547
TYR A 631
VAL A 656
TYR A 662
TYR A 666
ASN A 710
VAL A 711
HIS A 740
 SO4  A1769 ( 3.1A)
008  A1767 (-3.9A)
008  A1767 (-2.5A)
SO4  A1769 ( 4.5A)
None
None
008  A1767 (-4.4A)
008  A1767 (-3.8A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 0.22A 6b1eB-2bucA:
56.1		 6b1eB-2bucA:
88.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 GLU A 205
TYR A 547
SER A 630
TYR A 662
VAL A 711
 008  A1767 (-3.9A)
SO4  A1769 ( 4.5A)
SO4  A1769 ( 3.0A)
008  A1767 (-4.4A)
None
 1.30A 6b1eB-2bucA:
56.1		 6b1eB-2bucA:
88.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 TYR A 634
TYR A 662
ASN A 710
VAL A 711
HIS A 740
 None
008  A1767 (-4.4A)
008  A1767 (-3.0A)
None
SO4  A1769 ( 4.1A)
 1.02A 6b1eB-2bucA:
56.1		 6b1eB-2bucA:
88.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 6 ARG A 184
ILE A 194
ASN A 170
ASP A 171
 None
NAG  A1229 (-4.5A)
None
None
 1.36A 6dhbA-2bucA:
undetectable		 6dhbA-2bucA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		5 / 12 VAL A 688
VAL A 724
LEU A 723
GLY A 633
TYR A 661
 None
 1.15A 6drzA-2bucA:
undetectable		 6drzA-2bucA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 2buc DIPEPTIDYL PEPTIDASE
IV
(Sus
scrofa) 		4 / 6 ILE A 594
GLY A 549
TYR A 670
GLU A 602
 None
 1.13A 6gqiA-2bucA:
undetectable		 6gqiA-2bucA:
21.68