SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 2bud MALES-ABSENT ON THE
FIRST PROTEIN
(Drosophila
melanogaster) 		5 / 11 ARG A 387
ILE A 385
ILE A 432
GLY A 418
TYR A 413
 None
 1.23A 2azyA-2budA:
undetectable		 2azyA-2budA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 2bud MALES-ABSENT ON THE
FIRST PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 414
ILE A 375
MET A 370
ARG A 394
 None
 1.23A 3oezA-2budA:
undetectable		 3oezA-2budA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2bud MALES-ABSENT ON THE
FIRST PROTEIN
(Drosophila
melanogaster) 		4 / 5 VAL A 414
ILE A 375
MET A 370
ARG A 394
 None
 1.14A 3pyyB-2budA:
undetectable		 3pyyB-2budA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2bud MALES-ABSENT ON THE
FIRST PROTEIN
(Drosophila
melanogaster) 		3 / 3 GLU A 377
ASP A 374
ASP A 434
 None
 0.77A 4gc9A-2budA:
undetectable		 4gc9A-2budA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 2bud MALES-ABSENT ON THE
FIRST PROTEIN
(Drosophila
melanogaster) 		4 / 6 ASP A 367
GLY A 363
PRO A 409
THR A 402
 None
 1.06A 4l1aB-2budA:
undetectable		 4l1aB-2budA:
18.45