SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2buf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 9 VAL A 159
GLY A 157
ILE A 156
THR A  96
SER A  83
 NLG  A1302 ( 4.5A)
None
None
None
None
 1.23A 1gtnL-2bufA:
undetectable
1gtnM-2bufA:
undetectable		 1gtnL-2bufA:
15.67
1gtnM-2bufA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 267
GLY A 266
ALA A 202
ILE A  32
HIS A 271
 None
 1.25A 1kxhA-2bufA:
undetectable		 1kxhA-2bufA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_A_C2FA801_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 101
ASP A 130
ILE A 182
GLY A 186
SER A 193
 None
 1.48A 1q8jA-2bufA:
undetectable		 1q8jA-2bufA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 250
GLY A 251
MET A 252
LEU A 253
 None
 0.60A 1qzzA-2bufA:
4.6		 1qzzA-2bufA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 204
ILE A 182
THR A  29
 None
 0.81A 1rx3A-2bufA:
1.1		 1rx3A-2bufA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.28A 1v54A-2bufA:
1.2
1v54B-2bufA:
0.0
1v54T-2bufA:
0.0		 1v54A-2bufA:
22.06
1v54B-2bufA:
21.69
1v54T-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.33A 1v54G-2bufA:
0.0
1v54N-2bufA:
0.0
1v54O-2bufA:
0.0		 1v54G-2bufA:
14.04
1v54N-2bufA:
22.06
1v54O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.33A 1v55G-2bufA:
0.0
1v55N-2bufA:
0.0
1v55O-2bufA:
0.0		 1v55G-2bufA:
14.04
1v55N-2bufA:
22.06
1v55O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 7 PRO A 180
LEU A 126
GLY A 128
LEU A 170
 None
 0.78A 1ya4B-2bufA:
undetectable		 1ya4B-2bufA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.38A 2dyrG-2bufA:
0.0
2dyrN-2bufA:
0.0
2dyrO-2bufA:
0.0		 2dyrG-2bufA:
14.04
2dyrN-2bufA:
22.06
2dyrO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.34A 2eijG-2bufA:
0.0
2eijN-2bufA:
0.0
2eijO-2bufA:
0.0		 2eijG-2bufA:
14.04
2eijN-2bufA:
22.06
2eijO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.31A 2eikG-2bufA:
0.0
2eikN-2bufA:
0.0
2eikO-2bufA:
0.0		 2eikG-2bufA:
14.04
2eikN-2bufA:
22.06
2eikO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.34A 2eilG-2bufA:
0.0
2eilN-2bufA:
0.0
2eilO-2bufA:
0.0		 2eilG-2bufA:
14.04
2eilN-2bufA:
22.06
2eilO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CHDN1604_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.40A 2eimG-2bufA:
0.0
2eimN-2bufA:
0.2
2eimO-2bufA:
0.0		 2eimG-2bufA:
14.04
2eimN-2bufA:
22.06
2eimO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.27A 2zxwA-2bufA:
undetectable
2zxwB-2bufA:
0.0
2zxwT-2bufA:
0.0		 2zxwA-2bufA:
22.06
2zxwB-2bufA:
21.69
2zxwT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.29A 3abkA-2bufA:
0.7
3abkB-2bufA:
0.0
3abkT-2bufA:
0.0		 3abkA-2bufA:
22.06
3abkB-2bufA:
21.69
3abkT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.37A 3ablA-2bufA:
0.0
3ablB-2bufA:
0.0
3ablT-2bufA:
0.0		 3ablA-2bufA:
22.06
3ablB-2bufA:
21.69
3ablT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.33A 3ag1A-2bufA:
0.0
3ag1B-2bufA:
0.0
3ag1T-2bufA:
0.0		 3ag1A-2bufA:
22.06
3ag1B-2bufA:
21.69
3ag1T-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.25A 3ag1G-2bufA:
0.0
3ag1N-2bufA:
0.0
3ag1O-2bufA:
0.0		 3ag1G-2bufA:
14.04
3ag1N-2bufA:
22.06
3ag1O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.37A 3ag3A-2bufA:
0.0
3ag3B-2bufA:
0.0
3ag3T-2bufA:
0.0		 3ag3A-2bufA:
22.06
3ag3B-2bufA:
21.69
3ag3T-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.35A 3ag3G-2bufA:
0.0
3ag3N-2bufA:
0.0
3ag3O-2bufA:
0.0		 3ag3G-2bufA:
14.04
3ag3N-2bufA:
22.06
3ag3O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.26A 3asnA-2bufA:
0.0
3asnB-2bufA:
0.0
3asnT-2bufA:
0.0		 3asnA-2bufA:
22.06
3asnB-2bufA:
21.69
3asnT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.27A 3asoA-2bufA:
0.0
3asoB-2bufA:
0.0
3asoT-2bufA:
0.0		 3asoA-2bufA:
22.06
3asoB-2bufA:
21.69
3asoT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 7 THR A  96
VAL A  99
ILE A  72
THR A  92
 None
 0.84A 3deuA-2bufA:
undetectable		 3deuA-2bufA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 216
GLY A 186
ALA A 202
GLY A 203
ILE A 134
 None
 0.91A 3ku1A-2bufA:
3.6		 3ku1A-2bufA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 216
GLY A 186
ALA A 202
GLY A 203
ILE A 134
 None
 0.91A 3ku1C-2bufA:
3.6		 3ku1C-2bufA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 223
LEU A 231
ILE A 295
GLN A 238
ILE A 248
 None
 1.12A 4a7aB-2bufA:
undetectable		 4a7aB-2bufA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 101
ASP A 130
ILE A 182
GLY A 186
SER A 193
 None
 1.44A 4djfB-2bufA:
undetectable		 4djfB-2bufA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 204
ILE A 182
THR A  29
 None
 0.80A 4gh8A-2bufA:
undetectable		 4gh8A-2bufA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.31A 4oltA-2bufA:
undetectable		 4oltA-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.26A 4oltB-2bufA:
undetectable		 4oltB-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 9 VAL A 267
ILE A 243
VAL A 239
THR A 293
ALA A 270
 None
 1.18A 4oqrA-2bufA:
undetectable		 4oqrA-2bufA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.25A 4qwpA-2bufA:
undetectable		 4qwpA-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.25A 4qwpB-2bufA:
undetectable		 4qwpB-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.35A 5b1bG-2bufA:
0.0
5b1bN-2bufA:
0.0
5b1bO-2bufA:
0.0		 5b1bG-2bufA:
14.04
5b1bN-2bufA:
22.06
5b1bO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 239
ASN A 240
ILE A 243
ALA A 244
ILE A 295
 None
 0.83A 5j2tC-2bufA:
2.6		 5j2tC-2bufA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		3 / 3 SER A 269
SER A 296
PHE A  25
 None
 0.93A 5mugA-2bufA:
undetectable		 5mugA-2bufA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.39A 5x1fG-2bufA:
0.0
5x1fN-2bufA:
0.0
5x1fO-2bufA:
0.0		 5x1fG-2bufA:
14.04
5x1fN-2bufA:
22.06
5x1fO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A  37
PRO A  70
ILE A  72
VAL A 108
VAL A 100
 None
 1.41A 6j21A-2bufA:
undetectable		 6j21A-2bufA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.45A 6nknA-2bufA:
0.0
6nknB-2bufA:
0.0
6nknT-2bufA:
0.0		 6nknA-2bufA:
22.06
6nknB-2bufA:
21.69
6nknT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 221
GLY A 222
LEU A 223
GLY A 290
 None
 0.81A 6nm4A-2bufA:
undetectable		 6nm4A-2bufA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 10 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.39A 6nmfG-2bufA:
0.0
6nmfN-2bufA:
0.0
6nmfO-2bufA:
0.0		 6nmfG-2bufA:
14.04
6nmfN-2bufA:
22.06
6nmfO-2bufA:
21.69