SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2buk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A  47
SER A 186
SER A  34
ASN A  33
 None
 1.13A 1ig3A-2bukA:
3.0
1ig3B-2bukA:
3.4		 1ig3A-2bukA:
22.88
1ig3B-2bukA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.84A 2dyrP-2bukA:
undetectable
2dyrW-2bukA:
undetectable		 2dyrP-2bukA:
21.37
2dyrW-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.83A 2eikC-2bukA:
undetectable
2eikJ-2bukA:
undetectable		 2eikC-2bukA:
21.37
2eikJ-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.81A 2eikP-2bukA:
undetectable
2eikW-2bukA:
undetectable		 2eikP-2bukA:
21.37
2eikW-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.84A 2eilC-2bukA:
undetectable
2eilJ-2bukA:
undetectable		 2eilC-2bukA:
21.37
2eilJ-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.86A 2eilP-2bukA:
undetectable
2eilW-2bukA:
undetectable		 2eilP-2bukA:
21.37
2eilW-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.82A 3ag2C-2bukA:
undetectable		 3ag2C-2bukA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.84A 3ag2P-2bukA:
undetectable
3ag2W-2bukA:
undetectable		 3ag2P-2bukA:
21.37
3ag2W-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.84A 3ag4C-2bukA:
undetectable
3ag4J-2bukA:
undetectable		 3ag4C-2bukA:
21.37
3ag4J-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.79A 3ag4P-2bukA:
undetectable
3ag4W-2bukA:
undetectable		 3ag4P-2bukA:
21.37
3ag4W-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.88A 3asnC-2bukA:
undetectable
3asnJ-2bukA:
undetectable		 3asnC-2bukA:
21.37
3asnJ-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 8 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.85A 3asoC-2bukA:
undetectable
3asoJ-2bukA:
undetectable		 3asoC-2bukA:
21.37
3asoJ-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 6 GLN A 122
ILE A 118
PRO A 117
PHE A 125
 None
 0.89A 4fgkA-2bukA:
undetectable		 4fgkA-2bukA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.86A 5b1aC-2bukA:
undetectable
5b1aJ-2bukA:
undetectable		 5b1aC-2bukA:
21.37
5b1aJ-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.84A 5b1aP-2bukA:
undetectable
5b1aW-2bukA:
undetectable		 5b1aP-2bukA:
21.37
5b1aW-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		3 / 3 ASN A 148
SER A  69
ARG A  28
 None
 0.78A 5b2qA-2bukA:
undetectable		 5b2qA-2bukA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.86A 5b3sC-2bukA:
undetectable
5b3sJ-2bukA:
undetectable		 5b3sC-2bukA:
21.37
5b3sJ-2bukA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.83A 5b3sP-2bukA:
undetectable		 5b3sP-2bukA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.93A 5iy5C-2bukA:
undetectable
5iy5J-2bukA:
undetectable		 5iy5C-2bukA:
21.15
5iy5J-2bukA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2buk COAT PROTEIN
(unidentified
tobacco
necrosis
virus) 		4 / 7 LEU A 174
GLN A  45
PHE A 172
PHE A  90
 None
 0.90A 5z84C-2bukA:
undetectable
5z84J-2bukA:
undetectable		 5z84C-2bukA:
21.37
5z84J-2bukA:
15.54