SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 2bv6 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MGRA
(Staphylococcus
aureus) 		4 / 6 LEU A  44
LEU A  47
ILE A 105
ARG A 106
 None
 0.94A 2rlfB-2bv6A:
undetectable
2rlfC-2bv6A:
undetectable		 2rlfB-2bv6A:
16.94
2rlfC-2bv6A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 2bv6 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MGRA
(Staphylococcus
aureus) 		4 / 7 ARG A  84
ILE A  96
LEU A  64
THR A  37
 SO4  A1142 (-3.4A)
None
None
None
 1.03A 3nxuA-2bv6A:
undetectable		 3nxuA-2bv6A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2bv6 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MGRA
(Staphylococcus
aureus) 		3 / 3 THR A  37
HIS A  97
LEU A  47
 None
 0.84A 5axdC-2bv6A:
undetectable		 5axdC-2bv6A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 2bv6 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MGRA
(Staphylococcus
aureus) 		4 / 7 ARG A  84
ILE A  96
LEU A  64
THR A  37
 SO4  A1142 (-3.4A)
None
None
None
 1.00A 5vc0A-2bv6A:
undetectable		 5vc0A-2bv6A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 2bv6 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MGRA
(Staphylococcus
aureus) 		5 / 12 ILE A  82
VAL A  69
LEU A  81
THR A  37
LEU A  36
 None
 1.07A 6b54A-2bv6A:
undetectable		 6b54A-2bv6A:
20.32