SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 10 ALA A  90
GLU A  77
LEU A  74
ILE A  18
LEU A  24
 None
 1.29A 1a52B-2bv7A:
undetectable		 1a52B-2bv7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		3 / 3 ALA A  93
VAL A  88
TRP A  85
 None
 1.00A 1c4dA-2bv7A:
undetectable
1c4dB-2bv7A:
undetectable		 1c4dA-2bv7A:
9.17
1c4dB-2bv7A:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		3 / 3 ALA A  93
VAL A  88
TRP A  85
 None
 0.92A 1c4dC-2bv7A:
undetectable
1c4dD-2bv7A:
undetectable		 1c4dC-2bv7A:
9.17
1c4dD-2bv7A:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.99A 1drbB-2bv7A:
undetectable		 1drbB-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		4 / 6 HIS A 140
LEU A 136
PHE A 148
VAL A 144
 GM3  A1212 (-3.6A)
GM3  A1212 (-4.3A)
GM3  A1212 (-4.6A)
None
 1.02A 1ibgH-2bv7A:
undetectable		 1ibgH-2bv7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.90A 1ra2A-2bv7A:
undetectable		 1ra2A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.89A 1ra8A-2bv7A:
undetectable		 1ra8A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.92A 1rb2A-2bv7A:
undetectable		 1rb2A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.81A 1rb2B-2bv7A:
undetectable		 1rb2B-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 1.00A 1rd7A-2bv7A:
undetectable		 1rd7A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.93A 1re7B-2bv7A:
undetectable		 1re7B-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.90A 1rx2A-2bv7A:
undetectable		 1rx2A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.86A 1rx7A-2bv7A:
undetectable		 1rx7A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.89A 2d0kA-2bv7A:
undetectable		 2d0kA-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_B_FOLB2161_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.90A 2d0kB-2bv7A:
undetectable		 2d0kB-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		3 / 3 MET A 134
VAL A 209
GLU A 204
 None
GM3  A1212 (-4.6A)
SO4  A1210 ( 4.8A)
 0.82A 2x9gA-2bv7A:
undetectable		 2x9gA-2bv7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		4 / 5 PHE A 148
ILE A  45
GLY A 100
HIS A 140
 GM3  A1212 (-4.6A)
GM3  A1212 (-4.4A)
GM3  A1212 ( 3.7A)
GM3  A1212 (-3.6A)
 1.24A 3r0lD-2bv7A:
undetectable		 3r0lD-2bv7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.95A 4ej1A-2bv7A:
undetectable		 4ej1A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.92A 4fhbA-2bv7A:
undetectable		 4fhbA-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 1.00A 4i13A-2bv7A:
undetectable		 4i13A-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.97A 4p3rA-2bv7A:
undetectable		 4p3rA-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.95A 5eajA-2bv7A:
undetectable		 5eajA-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		3 / 3 LEU A 101
LEU A  30
ARG A 181
 None
GM3  A1212 ( 4.8A)
None
 0.58A 5hnzB-2bv7A:
undetectable		 5hnzB-2bv7A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.96A 5ujxA-2bv7A:
undetectable		 5ujxA-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.95A 5z6jA-2bv7A:
undetectable		 5z6jA-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		5 / 12 ILE A  18
LEU A  24
PHE A  23
LEU A 101
ILE A 194
 None
 0.94A 5z6kA-2bv7A:
undetectable		 5z6kA-2bv7A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		4 / 7 ILE A 111
LEU A 108
ARG A 125
LEU A  37
 None
GM3  A1212 ( 4.9A)
None
None
 0.91A 6nmpA-2bv7A:
2.2
6nmpJ-2bv7A:
undetectable		 6nmpA-2bv7A:
18.09
6nmpJ-2bv7A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2bv7 GLYCOLIPID TRANSFER
PROTEIN
(Bos
taurus) 		4 / 5 ILE A 111
LEU A 108
ARG A 125
LEU A  37
 None
GM3  A1212 ( 4.9A)
None
None
 0.92A 6nmpN-2bv7A:
1.9
6nmpW-2bv7A:
undetectable		 6nmpN-2bv7A:
18.09
6nmpW-2bv7A:
15.38