SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 12 GLU B 159
LEU B 156
ILE A   5
GLU B  97
TYR B 163
 None
 1.42A 1l7fA-2bv8B:
undetectable		 1l7fA-2bv8B:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 12 GLU B 159
LEU B 156
ILE A   5
GLU B  97
TYR B 163
 None
 1.42A 1l7hA-2bv8B:
undetectable		 1l7hA-2bv8B:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
(Gracilaria
chilensis) 		3 / 3 LEU A  92
VAL A  95
LEU A  99
 None
 0.53A 1mz9B-2bv8A:
undetectable		 1mz9B-2bv8A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 2bv8 C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		3 / 3 LEU B 113
TYR B 117
GLY B 121
 CYC  B1174 (-4.1A)
None
MEN  B  72 ( 4.7A)
 0.63A 2ocuA-2bv8B:
undetectable		 2ocuA-2bv8B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 12 ILE B  51
PHE B 164
ALA B  99
LEU A  19
ILE B  44
 None
 1.32A 2xkwB-2bv8B:
undetectable		 2xkwB-2bv8B:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
(Gracilaria
chilensis) 		5 / 11 LEU A  51
LEU A  44
SER A 143
LEU A 142
LEU A 154
 None
 0.77A 2xn5A-2bv8A:
undetectable		 2xn5A-2bv8A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 12 ILE A   9
ALA A  12
GLU A  23
LEU A  24
ILE B  44
 None
None
None
PEB  B1175 ( 4.6A)
None
 1.32A 2zzaA-2bv8A:
undetectable		 2zzaA-2bv8A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis;
Gracilaria
chilensis) 		5 / 11 ILE A   9
ALA A  12
GLU A  23
LEU A  24
ILE B  44
 None
None
None
PEB  B1175 ( 4.6A)
None
 1.34A 2zzaB-2bv8A:
undetectable		 2zzaB-2bv8A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 12 ILE A   9
ALA A  12
GLU A  23
LEU A  24
ILE B  44
 None
None
None
PEB  B1175 ( 4.6A)
None
 1.30A 3ia4B-2bv8A:
undetectable		 3ia4B-2bv8A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
(Gracilaria
chilensis) 		4 / 8 ASN A 151
THR A 152
SER A  37
ARG A  33
 None
 1.10A 3kp2A-2bv8A:
undetectable
3kp2B-2bv8A:
undetectable		 3kp2A-2bv8A:
25.41
3kp2B-2bv8A:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
(Gracilaria
chilensis) 		5 / 9 ASN A 151
THR A 152
ALA A  40
SER A  37
ARG A  33
 None
 1.48A 3kp6B-2bv8A:
1.5		 3kp6B-2bv8A:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 12 VAL B  41
SER B  94
LEU A  19
GLY B 100
ALA B  99
 None
 1.06A 3ln1D-2bv8B:
undetectable		 3ln1D-2bv8B:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		4 / 8 VAL B  41
LEU A  24
LEU B  38
ILE A   5
 None
PEB  B1175 ( 4.6A)
PEB  B1175 ( 4.0A)
None
 0.90A 3u5kD-2bv8B:
undetectable		 3u5kD-2bv8B:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
(Gracilaria
chilensis) 		4 / 8 LEU A  51
THR A  96
VAL A  95
ALA A  40
 None
 0.91A 3uniB-2bv8A:
undetectable		 3uniB-2bv8A:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		4 / 7 ASN B  35
LEU B  38
ARG B  37
TYR A  31
 PEB  B1175 (-3.6A)
PEB  B1175 ( 4.0A)
None
None
 1.02A 4cp3A-2bv8B:
undetectable
4cp3B-2bv8B:
undetectable		 4cp3A-2bv8B:
20.57
4cp3B-2bv8B:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 9 MET B 134
PHE B 164
LEU B 160
GLY B 161
ALA A   8
 None
 1.48A 4l6va-2bv8B:
0.0
4l6vf-2bv8B:
1.0		 4l6va-2bv8B:
12.93
4l6vf-2bv8B:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 9 VAL B  41
SER B  94
LEU A  19
GLY B 100
ALA B  99
 None
 1.01A 4rs0A-2bv8B:
undetectable		 4rs0A-2bv8B:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
(Gracilaria
chilensis) 		5 / 10 LEU A  51
LEU A  44
SER A 143
LEU A 142
LEU A 154
 None
 0.94A 4yiaA-2bv8A:
undetectable		 4yiaA-2bv8A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2bv8 C-PHYCOCYANIN ALPHA
SUBUNIT
C-PHYCOCYANIN BETA
SUBUNIT
(Gracilaria
chilensis) 		5 / 12 VAL B  41
SER B  94
LEU A  19
GLY B 100
ALA B  99
 None
 1.05A 5jvzB-2bv8B:
undetectable		 5jvzB-2bv8B:
14.42