SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bvg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 11 ALA A  99
LEU A 159
GLU A 199
ALA A 103
HIS A  95
 None
 1.18A 1mjlA-2bvgA:
undetectable
1mjlB-2bvgA:
undetectable		 1mjlA-2bvgA:
12.90
1mjlB-2bvgA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ARG A 449
GLY A  76
GLU A  64
ILE A  30
 None
 0.73A 1pk7B-2bvgA:
undetectable		 1pk7B-2bvgA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 7 ALA A 154
GLY A 142
GLY A 143
ASN A 413
PHE A 135
 None
None
FAD  A 600 (-3.0A)
FAD  A 600 (-3.8A)
None
 1.42A 2c49B-2bvgA:
undetectable		 2c49B-2bvgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 ASP A 273
ASP A 268
ASP A 239
 None
 0.65A 2igtA-2bvgA:
undetectable		 2igtA-2bvgA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 ASP A 273
ASP A 268
ASP A 239
 None
 0.67A 2igtB-2bvgA:
undetectable		 2igtB-2bvgA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 LEU A 231
LEU A 399
PRO A 218
GLY A 248
 None
 0.91A 2po5A-2bvgA:
undetectable		 2po5A-2bvgA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 LEU A 231
LEU A 399
PRO A 218
GLY A 248
 None
 0.89A 2po5B-2bvgA:
undetectable		 2po5B-2bvgA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 5 ARG A 276
ALA A 233
ASP A 232
GLU A 236
 None
 1.17A 2xrzA-2bvgA:
0.0		 2xrzA-2bvgA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 GLY A 137
GLY A  70
GLY A 134
 FAD  A 600 (-2.9A)
FAD  A 600 (-2.9A)
FAD  A 600 (-3.7A)
 0.42A 3bogC-2bvgA:
undetectable		 3bogC-2bvgA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 GLY A 143
TYR A 242
GLY A 128
MET A 129
 FAD  A 600 (-3.0A)
None
FAD  A 600 ( 3.7A)
FAD  A 600 (-4.8A)
 0.87A 3e9rA-2bvgA:
undetectable		 3e9rA-2bvgA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 GLY A 143
TYR A 242
GLY A 128
MET A 129
 FAD  A 600 (-3.0A)
None
FAD  A 600 ( 3.7A)
FAD  A 600 (-4.8A)
 0.84A 3e9rC-2bvgA:
undetectable		 3e9rC-2bvgA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 8 GLY A 142
ALA A 139
VAL A 198
GLY A 189
ILE A 158
 None
 1.20A 3ekpA-2bvgA:
undetectable		 3ekpA-2bvgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 10 ILE A 319
ILE A 351
VAL A 245
PRO A 218
LEU A 399
 None
 1.05A 3elzC-2bvgA:
undetectable		 3elzC-2bvgA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 10 ASP A 113
GLY A 134
LEU A 138
VAL A 198
ILE A 105
 None
FAD  A 600 (-3.7A)
FAD  A 600 (-3.9A)
None
None
 1.09A 3em4V-2bvgA:
undetectable		 3em4V-2bvgA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 9 PHE A 337
LEU A 399
ILE A 330
ALA A 331
ALA A 398
 None
 1.08A 3mdvA-2bvgA:
undetectable		 3mdvA-2bvgA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 10 VAL A 247
PHE A 337
ALA A 329
ILE A 319
VAL A 372
 None
 1.10A 3me6A-2bvgA:
undetectable		 3me6A-2bvgA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 11 LEU A 277
LEU A 280
LEU A 234
ASN A 235
LEU A 227
 None
 1.29A 3ndvA-2bvgA:
undetectable
3ndvB-2bvgA:
undetectable		 3ndvA-2bvgA:
25.27
3ndvB-2bvgA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 TYR A 293
GLU A 117
ALA A 118
GLY A 122
LEU A 202
 None
 1.46A 3ou6D-2bvgA:
undetectable		 3ou6D-2bvgA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 ALA A 392
ASP A 396
LEU A 399
LEU A 373
 None
 0.53A 3roxA-2bvgA:
undetectable		 3roxA-2bvgA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ARG A 291
SER A 287
ILE A 288
PHE A 146
ALA A 298
 None
 1.31A 3ua1A-2bvgA:
undetectable		 3ua1A-2bvgA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 LYS A 348
GLU A 350
TRP A 314
 None
 1.23A 3v4tH-2bvgA:
undetectable		 3v4tH-2bvgA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ILE A 158
ILE A  96
PHE A 135
LEU A 114
LEU A 138
 None
None
None
None
FAD  A 600 (-3.9A)
 1.29A 3vw1B-2bvgA:
undetectable		 3vw1B-2bvgA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 TYR A 242
GLY A 128
GLY A 145
ASN A 300
ASN A 413
 None
FAD  A 600 ( 3.7A)
None
None
FAD  A 600 (-3.8A)
 1.23A 3vywB-2bvgA:
undetectable		 3vywB-2bvgA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ILE A 241
VAL A 259
PHE A 146
ILE A 288
VAL A 303
 None
 1.10A 3w68C-2bvgA:
undetectable		 3w68C-2bvgA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_B_HQEB200_1
(FLAVOREDOXIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 5 TYR A 452
VAL A 418
ARG A  34
HIS A  35
 None
 1.40A 3zofB-2bvgA:
0.0		 3zofB-2bvgA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 GLY A  71
GLY A  70
ASN A  80
GLY A  83
ASP A  87
 FAD  A 600 (-3.2A)
FAD  A 600 (-2.9A)
None
None
None
 1.03A 4fp9C-2bvgA:
undetectable		 4fp9C-2bvgA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 LEU A 299
PHE A 246
SER A 244
LEU A 277
THR A 258
 None
 1.37A 4iarA-2bvgA:
undetectable		 4iarA-2bvgA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 PHE A 326
PHE A 337
ALA A 329
ALA A 331
VAL A 257
 None
 1.01A 4j6dA-2bvgA:
undetectable		 4j6dA-2bvgA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 PHE A 326
PHE A 337
ALA A 329
ALA A 331
VAL A 257
 None
 1.03A 4j6dB-2bvgA:
undetectable		 4j6dB-2bvgA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 PHE A 326
PHE A 337
ALA A 329
ALA A 331
VAL A 257
 None
 1.04A 4jbtA-2bvgA:
undetectable		 4jbtA-2bvgA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 8 PRO A 149
LEU A 264
VAL A 296
VAL A 261
 None
 1.01A 4pwdA-2bvgA:
3.0		 4pwdA-2bvgA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 5 ILE A 110
VAL A 109
PHE A 121
HIS A  72
 None
None
None
FAD  A 600 (-2.4A)
 1.33A 4rzvA-2bvgA:
undetectable		 4rzvA-2bvgA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 GLU A 117
ALA A 118
PHE A 121
 None
 0.56A 4v1fA-2bvgA:
undetectable		 4v1fA-2bvgA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 GLU A 117
ALA A 118
PHE A 121
 None
 0.59A 4v1fC-2bvgA:
undetectable		 4v1fC-2bvgA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 ARG A 317
GLY A 408
SER A 407
LEU A 400
 None
 1.26A 5bphD-2bvgA:
undetectable		 5bphD-2bvgA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 LEU A 334
PHE A 337
VAL A 249
PRO A 255
GLY A 281
 None
 1.21A 5f9zB-2bvgA:
undetectable		 5f9zB-2bvgA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ILE A 351
GLU A 352
GLY A 353
ARG A 367
GLU A 236
 None
 1.12A 5fhzD-2bvgA:
undetectable		 5fhzD-2bvgA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ILE A 351
LEU A 231
PRO A 243
GLY A 371
GLY A 353
 None
 1.07A 5nnaB-2bvgA:
undetectable		 5nnaB-2bvgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ILE A 351
LEU A 231
PRO A 243
GLY A 371
GLY A 353
 None
 1.06A 5nnaC-2bvgA:
undetectable		 5nnaC-2bvgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 9 ALA A 331
ILE A 351
LEU A 349
ILE A 319
ALA A 224
 None
 1.01A 5nunA-2bvgA:
1.3		 5nunA-2bvgA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 GLY A 152
LEU A 153
HIS A 366
 None
 0.70A 5u63A-2bvgA:
undetectable		 5u63A-2bvgA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 8 LEU A 234
VAL A 261
HIS A 263
LEU A 280
ILE A 274
 None
 1.25A 5v0vA-2bvgA:
2.1		 5v0vA-2bvgA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 7 PHE A 182
ILE A 158
GLY A 189
TYR A 452
 None
 0.88A 5x5qC-2bvgA:
undetectable		 5x5qC-2bvgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 PHE A 182
ILE A 158
GLY A 189
TYR A 452
 None
 0.91A 5x5qE-2bvgA:
undetectable		 5x5qE-2bvgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 VAL A  55
ILE A  65
VAL A  67
PHE A  24
LEU A  88
 None
None
FAD  A 600 (-3.8A)
None
FAD  A 600 (-4.6A)
 1.21A 6ajiA-2bvgA:
3.8		 6ajiA-2bvgA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 LEU A 435
GLY A 187
GLY A 189
GLY A 193
PRO A 456
 None
 1.08A 6ce2B-2bvgA:
undetectable		 6ce2B-2bvgA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		5 / 10 ALA A 139
VAL A 200
ILE A 105
GLY A 107
ILE A 158
 None
None
None
FAD  A 600 (-3.6A)
None
 0.99A 6dj2A-2bvgA:
undetectable		 6dj2A-2bvgA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		4 / 7 ARG A 104
TYR A 172
LEU A 163
VAL A 195
 None
None
None
FAD  A 600 (-3.9A)
 1.02A 6g2pA-2bvgA:
undetectable		 6g2pA-2bvgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 2bvg 6-HYDROXY-D-NICOTINE
OXIDASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 TRP A  31
ILE A  30
ASP A  32
 FAD  A 600 (-3.6A)
None
None
 0.84A 6i0y7-2bvgA:
undetectable		 6i0y7-2bvgA:
8.38