SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bwb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2bwb UBIQUITIN-LIKE
PROTEIN DSK2
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 358
GLY A 359
SER A 360
GLY A 363
ASP A 366
 None
 0.95A 3huoB-2bwbA:
undetectable		 3huoB-2bwbA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 2bwb UBIQUITIN-LIKE
PROTEIN DSK2
(Saccharomyces
cerevisiae) 		4 / 5 ALA A 353
SER A 357
GLY A 358
TYR A 332
 None
 1.23A 5yodD-2bwbA:
undetectable		 5yodD-2bwbA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 2bwb UBIQUITIN-LIKE
PROTEIN DSK2
(Saccharomyces
cerevisiae) 		4 / 5 ALA A 364
SER A 357
GLY A 358
TYR A 332
 None
 1.27A 5yodD-2bwbA:
undetectable		 5yodD-2bwbA:
16.56