SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 HIS A 142
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.4A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.12A 1eqbA-2bwpA:
28.5
1eqbB-2bwpA:
28.6		 1eqbA-2bwpA:
23.80
1eqbB-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 SER A 189
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.6A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.19A 1eqbA-2bwpA:
28.5
1eqbB-2bwpA:
28.6		 1eqbA-2bwpA:
23.80
1eqbB-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 HIS A 142
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.4A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.12A 1eqbA-2bwpA:
28.5
1eqbB-2bwpA:
28.6		 1eqbA-2bwpA:
23.80
1eqbB-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 SER A 189
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.6A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.19A 1eqbA-2bwpA:
28.5
1eqbB-2bwpA:
28.6		 1eqbA-2bwpA:
23.80
1eqbB-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 HIS A 142
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.4A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.12A 1eqbC-2bwpA:
28.5
1eqbD-2bwpA:
28.1		 1eqbC-2bwpA:
23.80
1eqbD-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 SER A 189
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.6A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.19A 1eqbC-2bwpA:
28.5
1eqbD-2bwpA:
28.1		 1eqbC-2bwpA:
23.80
1eqbD-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 HIS A 142
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.4A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.12A 1eqbC-2bwpA:
28.5
1eqbD-2bwpA:
28.1		 1eqbC-2bwpA:
23.80
1eqbD-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 SER A 189
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.6A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.19A 1eqbC-2bwpA:
28.5
1eqbD-2bwpA:
28.1		 1eqbC-2bwpA:
23.80
1eqbD-2bwpA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 6 ASN A 362
HIS A  15
TYR A  20
GLY A  18
 None
 1.45A 1mxdA-2bwpA:
undetectable		 1mxdA-2bwpA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 12 LEU A 350
VAL A 356
GLY A 355
LEU A 396
ALA A 392
 None
 0.97A 2egvA-2bwpA:
undetectable		 2egvA-2bwpA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 12 LEU A 350
VAL A 356
GLY A 355
LEU A 396
ALA A 392
 None
 1.00A 2egvB-2bwpA:
undetectable		 2egvB-2bwpA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 10 ARG A  84
ILE A 257
GLY A 255
PHE A 112
TYR A 250
 None
 1.11A 2tsrC-2bwpA:
undetectable		 2tsrC-2bwpA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 7 HIS A 142
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.4A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.11A 2vmyA-2bwpA:
28.7
2vmyB-2bwpA:
28.0		 2vmyA-2bwpA:
26.77
2vmyB-2bwpA:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 HIS A 142
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.4A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.17A 2vmyA-2bwpA:
28.7
2vmyB-2bwpA:
27.9		 2vmyA-2bwpA:
26.77
2vmyB-2bwpA:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 SER A 189
HIS A 217
LYS A 248
ARG A 374
 PLG  A 500 (-3.6A)
PLG  A 500 (-3.8A)
PLG  A 500 (-2.7A)
PLG  A 500 ( 4.0A)
 1.27A 2vmyA-2bwpA:
28.7
2vmyB-2bwpA:
27.9		 2vmyA-2bwpA:
26.77
2vmyB-2bwpA:
26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 12 ASP A  55
GLY A  58
SER A 291
LEU A 303
ALA A 249
 None
 0.85A 3d91B-2bwpA:
undetectable		 3d91B-2bwpA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 7 GLY A 226
GLY A 223
GLU A 231
GLU A  99
 None
 0.88A 3fpjB-2bwpA:
2.3		 3fpjB-2bwpA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 12 GLY A 254
GLY A 255
VAL A 111
MET A  69
ILE A 100
 None
 0.98A 3h52B-2bwpA:
undetectable		 3h52B-2bwpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 12 TYR A 212
ILE A 100
GLY A 244
ALA A 247
ILE A 257
 None
None
None
PLG  A 500 ( 4.0A)
None
 0.85A 3jayA-2bwpA:
3.4		 3jayA-2bwpA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 12 ASP A 163
ARG A 157
ILE A 135
ALA A 178
ALA A 173
 None
 0.98A 3ua1A-2bwpA:
0.0		 3ua1A-2bwpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 11 GLY A 208
ALA A 204
ILE A 182
ILE A 135
LEU A 133
 None
 1.04A 4dt8A-2bwpA:
undetectable		 4dt8A-2bwpA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 10 GLY A 208
ALA A 204
ILE A 182
ILE A 135
LEU A 133
 None
 1.10A 4dt8B-2bwpA:
undetectable		 4dt8B-2bwpA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 4 ILE A  26
VAL A 356
VAL A  50
ARG A  28
 None
 0.98A 4m6tA-2bwpA:
undetectable		 4m6tA-2bwpA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 9 ALA A 285
ALA A 286
LEU A  73
LEU A 246
VAL A 252
 None
 1.11A 4or0A-2bwpA:
undetectable		 4or0A-2bwpA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 8 LEU A  96
LEU A 103
PHE A 242
GLY A 244
 None
 0.90A 4r3aA-2bwpA:
undetectable		 4r3aA-2bwpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 9 SER A 137
ALA A 183
LEU A 133
ILE A 134
 None
 0.89A 4xtaA-2bwpA:
undetectable		 4xtaA-2bwpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 5 ASN A 162
ASP A 138
ASN A 141
ASP A 214
 None
None
None
PLG  A 500 (-3.1A)
 1.44A 5vooA-2bwpA:
undetectable		 5vooA-2bwpA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 5 ASN A 162
ASP A 138
ASN A 141
ASP A 214
 None
None
None
PLG  A 500 (-3.1A)
 1.44A 5vooC-2bwpA:
undetectable		 5vooC-2bwpA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 5 ASN A 162
ASP A 138
ASN A 141
ASP A 214
 None
None
None
PLG  A 500 (-3.1A)
 1.45A 5vooE-2bwpA:
undetectable		 5vooE-2bwpA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 7 LEU A  57
ASP A  55
TYR A 250
HIS A 142
 None
None
None
PLG  A 500 (-3.4A)
 1.18A 5w97C-2bwpA:
undetectable
5w97a-2bwpA:
undetectable
5w97c-2bwpA:
undetectable		 5w97C-2bwpA:
18.25
5w97a-2bwpA:
23.30
5w97c-2bwpA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 12 LEU A 133
GLY A 132
TYR A 136
THR A 125
ALA A 209
 None
 1.23A 5x5qB-2bwpA:
undetectable		 5x5qB-2bwpA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		5 / 11 SER A 260
ALA A 259
THR A 211
LEU A 181
ALA A 204
 None
 1.40A 6efnA-2bwpA:
undetectable		 6efnA-2bwpA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2bwp 5-AMINOLEVULINATE
SYNTHASE
(Rhodobacter
capsulatus) 		4 / 5 ALA A 288
TYR A 250
GLN A 289
ILE A 100
 None
 1.38A 6f6sA-2bwpA:
undetectable
6f6sB-2bwpA:
undetectable		 6f6sA-2bwpA:
10.95
6f6sB-2bwpA:
12.77