SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bwq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XZX_X_T3X500_2 (THYROID HORMONE RECEPTOR BETA-1)	2bwq	REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 (Rattus norvegicus)	3 / 3	PHE A 798 ARG A 811 ASN A 779	None	0.82A	1xzxX-2bwqA: undetectable	1xzxX-2bwqA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB1283_1 (CES1 PROTEIN)	2bwq	REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 (Rattus norvegicus)	4 / 7	PRO A 765 LEU A 831 GLY A 832 LEU A 754	None	0.90A	1ya4B-2bwqA: undetectable	1ya4B-2bwqA: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GAN_A_SVRA158_1 (UNCHARACTERIZED PROTEIN AT3G22680)	2bwq	REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 (Rattus norvegicus)	5 / 11	GLN A 743 VAL A 803 PRO A 802 ILE A 836 ILE A 769	None	1.47A	3ganA-2bwqA: undetectable	3ganA-2bwqA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_A_SAMA501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	2bwq	REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 (Rattus norvegicus)	5 / 12	PRO A 762 GLY A 760 GLY A 832 LEU A 731 LEU A 852	None	1.17A	5wwsA-2bwqA: undetectable	5wwsA-2bwqA: 16.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XZX_X_T3X500_2","THYROID HORMONE RECEPTOR BETA-1","2bwq","REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2","Rattus norvegicus",3,"PHE A 798;ARG A 811;ASN A 779","None","0.82A","1xzxX-2bwqA:undetectable","1xzxX-2bwqA:20.00"],["1YA4_B_CTXB1283_1","CES1 PROTEIN","2bwq","REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2","Rattus norvegicus",4,"PRO A 765;LEU A 831;GLY A 832;LEU A 754","None","0.90A","1ya4B-2bwqA:undetectable","1ya4B-2bwqA:15.11"],["3GAN_A_SVRA158_1","UNCHARACTERIZED PROTEIN AT3G22680","2bwq","REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2","Rattus norvegicus",5,"GLN A 743;VAL A 803;PRO A 802;ILE A 836;ILE A 769","None","1.47A","3ganA-2bwqA:undetectable","3ganA-2bwqA:21.95"],["5WWS_A_SAMA501_0","PUTATIVE METHYLTRANSFERASE NSUN6","2bwq","REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2","Rattus norvegicus",5,"PRO A 762;GLY A 760;GLY A 832;LEU A 731;LEU A 852","None","1.17A","5wwsA-2bwqA:undetectable","5wwsA-2bwqA:16.37"]]