SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bws'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 8 SER A 353
LEU A 301
TYR A 304
PRO A 384
 None
 1.02A 1fduB-2bwsA:
undetectable		 1fduB-2bwsA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		3 / 3 PHE A 219
TYR A 229
PRO A 227
 None
 0.96A 1mcnA-2bwsA:
undetectable
1mcnB-2bwsA:
undetectable
1mcnP-2bwsA:
undetectable		 1mcnA-2bwsA:
18.41
1mcnB-2bwsA:
18.41
1mcnP-2bwsA:
2.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		3 / 3 PHE A 282
LEU A 256
MET A 251
 None
 0.90A 1mx1D-2bwsA:
undetectable		 1mx1D-2bwsA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 THR A 381
ALA A 421
GLY A 262
HIS A 195
TYR A 229
 MN  A1441 ( 3.5A)
None
None
None
None
 1.26A 1nbiC-2bwsA:
undetectable		 1nbiC-2bwsA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 THR A 381
ALA A 421
GLY A 262
HIS A 195
TYR A 229
 MN  A1441 ( 3.5A)
None
None
None
None
 1.26A 1nbiD-2bwsA:
undetectable		 1nbiD-2bwsA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.82A 1rl8A-2bwsA:
undetectable		 1rl8A-2bwsA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.83A 1rl8B-2bwsA:
undetectable		 1rl8B-2bwsA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 5 PRO A 390
GLY A 239
ASN A 238
GLY A 236
 None
None
CSO  A 249 ( 3.9A)
None
 1.03A 1zlqA-2bwsA:
undetectable		 1zlqA-2bwsA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 7 LEU A 433
ILE A 259
VAL A 424
ILE A 430
 None
 0.69A 2aojB-2bwsA:
undetectable		 2aojB-2bwsA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 10 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.91A 2aquA-2bwsA:
undetectable		 2aquA-2bwsA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 9 LEU A 433
ILE A 403
ILE A 259
VAL A 424
ILE A 430
 None
 1.11A 2avoA-2bwsA:
undetectable		 2avoA-2bwsA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.84A 2fxeA-2bwsA:
undetectable		 2fxeA-2bwsA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 11 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.87A 2fxeB-2bwsA:
undetectable		 2fxeB-2bwsA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.79A 2nmyA-2bwsA:
undetectable		 2nmyA-2bwsA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 8 THR A 420
VAL A 423
GLU A 406
ARG A 274
 None
None
MN  A1442 ( 2.4A)
None
 1.11A 2v41G-2bwsA:
undetectable
2v41H-2bwsA:
undetectable		 2v41G-2bwsA:
19.23
2v41H-2bwsA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 5 SER A 235
GLY A 205
GLU A 208
CYH A 202
 CSO  A 249 ( 4.7A)
None
CSO  A 249 ( 3.5A)
None
 0.93A 3aiaA-2bwsA:
undetectable
3aiaB-2bwsA:
undetectable		 3aiaA-2bwsA:
20.51
3aiaB-2bwsA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		3 / 3 LEU A 102
VAL A  63
ARG A  12
 None
 0.73A 3b0wB-2bwsA:
undetectable		 3b0wB-2bwsA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.84A 3ekwB-2bwsA:
undetectable		 3ekwB-2bwsA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 8 GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
MN  A1442 (-2.0A)
None
 0.63A 3el0A-2bwsA:
undetectable		 3el0A-2bwsA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 11 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.82A 3em4U-2bwsA:
undetectable		 3em4U-2bwsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 GLY A 357
ARG A 173
ASP A 408
GLY A 262
ARG A  44
 None
 1.23A 3k13B-2bwsA:
undetectable		 3k13B-2bwsA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 GLY A 357
ARG A 173
ASP A 408
GLY A 262
ARG A  44
 None
 1.23A 3k13C-2bwsA:
undetectable		 3k13C-2bwsA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.81A 3ndwA-2bwsA:
undetectable		 3ndwA-2bwsA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.82A 3ndxA-2bwsA:
undetectable		 3ndxA-2bwsA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 11 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.87A 3ndxB-2bwsA:
undetectable		 3ndxB-2bwsA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		3 / 3 GLY A 402
ILE A 292
VAL A 293
 None
 0.35A 3nv6A-2bwsA:
undetectable		 3nv6A-2bwsA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.74A 3oxxC-2bwsA:
undetectable		 3oxxC-2bwsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 GLY A  54
GLU A   7
ARG A  11
VAL A 183
ALA A 182
 None
 1.10A 3t7vA-2bwsA:
undetectable		 3t7vA-2bwsA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 5 ASN A  46
ALA A  30
TYR A 136
ALA A 137
 None
 1.36A 3twpD-2bwsA:
undetectable		 3twpD-2bwsA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 9 PRO A 277
GLN A 286
LEU A 294
ILE A 430
MET A 434
 None
 1.26A 4c66A-2bwsA:
undetectable		 4c66A-2bwsA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 8 ARG A 221
GLY A 262
ALA A 261
ASP A 260
 None
None
None
MN  A1442 (-2.0A)
 0.83A 4eyrB-2bwsA:
undetectable		 4eyrB-2bwsA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ARG A 221
GLY A 262
ALA A 261
ASP A 260
ILE A 215
 None
None
None
MN  A1442 (-2.0A)
None
 0.90A 4njvA-2bwsA:
undetectable		 4njvA-2bwsA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		3 / 3 ASP A 271
ASP A 260
ASN A 230
 MN  A1442 ( 2.4A)
MN  A1442 (-2.0A)
None
 0.84A 4q5mA-2bwsA:
undetectable		 4q5mA-2bwsA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 11 LEU A 433
ILE A 403
ILE A 259
VAL A 424
ILE A 430
 None
 0.93A 4qgiB-2bwsA:
undetectable		 4qgiB-2bwsA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 11 ILE A 272
GLY A 262
ASP A 408
GLU A 383
THR A 420
 None
None
None
MN  A1441 (-2.5A)
None
 1.37A 4xt7A-2bwsA:
undetectable		 4xt7A-2bwsA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 5 TYR A  51
TRP A  50
LEU A 184
LEU A 174
 None
 1.38A 5eshA-2bwsA:
undetectable		 5eshA-2bwsA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ILE A  27
PHE A  49
ALA A  25
LEU A 102
LEU A  76
 None
 1.25A 5jkvA-2bwsA:
undetectable		 5jkvA-2bwsA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 11 LEU A 433
ILE A 403
ILE A 259
VAL A 424
ILE A 430
 None
 0.91A 5kr2B-2bwsA:
undetectable		 5kr2B-2bwsA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 9 LEU A 433
ILE A 403
ILE A 259
VAL A 424
ILE A 430
 None
 1.04A 5kr2D-2bwsA:
undetectable		 5kr2D-2bwsA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 5 ARG A 274
THR A 196
HIS A 195
ALA A 192
 None
 1.33A 5mfxA-2bwsA:
2.3		 5mfxA-2bwsA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 ILE A 215
GLY A 213
HIS A 210
ILE A 272
ALA A 261
 None
 1.10A 5n0sA-2bwsA:
undetectable		 5n0sA-2bwsA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		4 / 8 ARG A 287
ILE A 320
LEU A 386
GLY A 385
 None
 0.92A 5nooD-2bwsA:
undetectable		 5nooD-2bwsA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 11 LEU A 301
ILE A 409
LEU A 297
SER A 296
VAL A 382
 None
 0.89A 5twjD-2bwsA:
undetectable		 5twjD-2bwsA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 2bws XAA-PRO
AMINOPEPTIDASE P
(Escherichia
coli) 		5 / 12 GLY A 402
ILE A 272
ALA A 261
THR A 231
GLY A 239
 None
 0.99A 5veuH-2bwsA:
0.9		 5veuH-2bwsA:
20.90