SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2byf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 2byf PHOSPHOLIPASE C,
EPSILON 1
(Homo
sapiens) 		3 / 3 ASP A  13
LEU A 105
LEU A 103
 None
 0.72A 1np1B-2byfA:
undetectable		 1np1B-2byfA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2byf PHOSPHOLIPASE C,
EPSILON 1
(Homo
sapiens) 		4 / 6 LEU A  39
THR A  38
LEU A  59
ASP A  56
 None
 0.95A 2wm3A-2byfA:
undetectable		 2wm3A-2byfA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 2byf PHOSPHOLIPASE C,
EPSILON 1
(Homo
sapiens) 		4 / 8 SER A  45
VAL A  22
LEU A  20
PRO A  19
 None
 1.15A 3jq7C-2byfA:
undetectable		 3jq7C-2byfA:
18.02