SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bz0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 2bz0 GTP CYCLOHYDROLASE
II
(Escherichia
coli) 		4 / 7 VAL A  50
LEU A 147
THR A 149
LEU A 171
 None
None
G2P  A1176 (-3.7A)
None
 0.88A 1jgsA-2bz0A:
undetectable		 1jgsA-2bz0A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2bz0 GTP CYCLOHYDROLASE
II
(Escherichia
coli) 		4 / 6 GLY A  93
THR A 114
GLU A  92
GLU A  53
 G2P  A1176 (-3.4A)
G2P  A1176 (-2.9A)
G2P  A1176 (-4.3A)
None
 0.99A 3fpjA-2bz0A:
undetectable		 3fpjA-2bz0A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2bz0 GTP CYCLOHYDROLASE
II
(Escherichia
coli) 		4 / 8 HIS A  89
ASN A  95
ASP A 135
LEU A 132
 None
 1.05A 4k0bA-2bz0A:
undetectable		 4k0bA-2bz0A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2bz0 GTP CYCLOHYDROLASE
II
(Escherichia
coli) 		4 / 8 HIS A  89
ASN A  95
ASP A 135
LEU A 132
 None
 1.04A 4l7iA-2bz0A:
undetectable		 4l7iA-2bz0A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 2bz0 GTP CYCLOHYDROLASE
II
(Escherichia
coli) 		4 / 6 ALA A  74
GLN A  77
LEU A  86
LEU A  47
 None
 1.25A 4xp3A-2bz0A:
undetectable		 4xp3A-2bz0A:
19.43