SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.40A	1oe1A-2bz7A: undetectable	1oe1A-2bz7A: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	5 / 5	HIS A 37 CYH A 87 PRO A 89 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 ( 4.5A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.70A	1oe2A-2bz7A: 6.8	1oe2A-2bz7A: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.42A	1oe3A-2bz7A: 3.9	1oe3A-2bz7A: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.32A	2fqdA-2bz7A: undetectable	2fqdA-2bz7A: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.31A	2fqeA-2bz7A: undetectable	2fqeA-2bz7A: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.29A	2fqfA-2bz7A: undetectable	2fqfA-2bz7A: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.29A	2fqgA-2bz7A: undetectable	2fqgA-2bz7A: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.38A	2xxgA-2bz7A: 6.5	2xxgA-2bz7A: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	5 / 5	HIS A 37 CYH A 87 PRO A 89 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 ( 4.5A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.75A	2xxgC-2bz7A: 6.6	2xxgC-2bz7A: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TAJ_A_NBOA700_1 (LACTOTRANSFERRIN)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 7	GLY A 10 ASN A 11 TYR A 15 THR A 30	None	0.65A	3tajA-2bz7A: undetectable	3tajA-2bz7A: 14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 4	HIS A 37 CYH A 87 HIS A 90 MET A 95	CU A 103 (-3.1A) CU A 103 (-2.2A) CU A 103 (-3.2A) CU A 103 (-2.8A)	0.27A	4ef3A-2bz7A: undetectable	4ef3A-2bz7A: 11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUO_D_08HD501_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2)	2bz7	PLASTOCYANIN (Dryopteris crassirhizoma)	4 / 8	TYR A 83 PHE A 41 PHE A 29 VAL A 21	None	1.04A	6huoC-2bz7A: undetectable 6huoD-2bz7A: undetectable	6huoC-2bz7A: 21.50 6huoD-2bz7A: 17.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.40A","1oe1A-2bz7A:undetectable","1oe1A-2bz7A:19.44"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",5,"HIS A  37;CYH A  87;PRO A  89;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 ( 4.5A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.70A","1oe2A-2bz7A:6.8","1oe2A-2bz7A:19.44"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.42A","1oe3A-2bz7A:3.9","1oe3A-2bz7A:19.44"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.32A","2fqdA-2bz7A:undetectable","2fqdA-2bz7A:13.00"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.31A","2fqeA-2bz7A:undetectable","2fqeA-2bz7A:13.00"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.29A","2fqfA-2bz7A:undetectable","2fqfA-2bz7A:13.00"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.29A","2fqgA-2bz7A:undetectable","2fqgA-2bz7A:13.00"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.38A","2xxgA-2bz7A:6.5","2xxgA-2bz7A:19.10"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",5,"HIS A  37;CYH A  87;PRO A  89;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 ( 4.5A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.75A","2xxgC-2bz7A:6.6","2xxgC-2bz7A:19.10"],["3TAJ_A_NBOA700_1","LACTOTRANSFERRIN","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"GLY A  10;ASN A  11;TYR A  15;THR A  30","None","0.65A","3tajA-2bz7A:undetectable","3tajA-2bz7A:14.41"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"HIS A  37;CYH A  87;HIS A  90;MET A  95"," CU A 103 (-3.1A); CU A 103 (-2.2A); CU A 103 (-3.2A); CU A 103 (-2.8A)","0.27A","4ef3A-2bz7A:undetectable","4ef3A-2bz7A:11.66"],["6HUO_D_08HD501_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","2bz7","PLASTOCYANIN","Dryopteris crassirhizoma",4,"TYR A  83;PHE A  41;PHE A  29;VAL A  21","None","1.04A","6huoC-2bz7A:undetectable;6huoD-2bz7A:undetectable","6huoC-2bz7A:21.50;6huoD-2bz7A:17.65"]]