SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2bzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.96A 1dhiA-2bzuA:
undetectable		 1dhiA-2bzuA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
SER A 243
ILE A 244
LEU A 284
ILE A 269
 None
 0.70A 1dhiA-2bzuA:
undetectable		 1dhiA-2bzuA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 11 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.96A 1dhiB-2bzuA:
undetectable		 1dhiB-2bzuA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
SER A 243
ILE A 244
LEU A 284
ILE A 269
 None
 0.73A 1dhjA-2bzuA:
undetectable		 1dhjA-2bzuA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.95A 1dhjB-2bzuA:
undetectable		 1dhjB-2bzuA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.93A 1draA-2bzuA:
undetectable		 1draA-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
SER A 243
ILE A 244
LEU A 284
ILE A 269
 None
 0.70A 1draA-2bzuA:
undetectable		 1draA-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.94A 1draB-2bzuA:
undetectable		 1draB-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.95A 1drbA-2bzuA:
undetectable		 1drbA-2bzuA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
SER A 243
ILE A 244
LEU A 284
ILE A 269
 None
 0.68A 1drbA-2bzuA:
undetectable		 1drbA-2bzuA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.95A 1drbB-2bzuA:
undetectable		 1drbB-2bzuA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.98A 1rb2A-2bzuA:
undetectable		 1rb2A-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.83A 1rb3B-2bzuA:
undetectable		 1rb3B-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.88A 1rd7A-2bzuA:
undetectable		 1rd7A-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		4 / 6 SER A 367
ALA A 283
THR A 348
ASN A 338
 None
 1.14A 1yvpB-2bzuA:
undetectable		 1yvpB-2bzuA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		4 / 8 PHE A 381
LEU A 256
LEU A 288
LEU A 286
 None
 0.98A 2bfpC-2bzuA:
undetectable		 2bfpC-2bzuA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.94A 2drcA-2bzuA:
undetectable		 2drcA-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
SER A 243
ILE A 244
LEU A 284
ILE A 269
 None
 0.69A 2drcA-2bzuA:
undetectable		 2drcA-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.90A 2drcB-2bzuA:
undetectable		 2drcB-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		4 / 7 MET A 322
VAL A 327
THR A 326
ARG A 330
 None
 1.01A 2kotA-2bzuA:
undetectable		 2kotA-2bzuA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 LEU A 254
ILE A 269
LEU A 284
ILE A 267
PHE A 290
 None
 1.06A 2ygqA-2bzuA:
undetectable		 2ygqA-2bzuA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		4 / 5 ILE A 236
SER A 237
PRO A 238
PRO A 240
 None
 1.40A 3bjwC-2bzuA:
undetectable		 3bjwC-2bzuA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.96A 3drcA-2bzuA:
undetectable		 3drcA-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
SER A 243
ILE A 244
LEU A 284
ILE A 269
 None
 0.71A 3drcA-2bzuA:
undetectable		 3drcA-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.93A 3drcB-2bzuA:
undetectable		 3drcB-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.76A 3tq9A-2bzuA:
undetectable		 3tq9A-2bzuA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
SER A 243
ILE A 244
LEU A 284
ILE A 269
 None
 0.95A 3tq9A-2bzuA:
undetectable		 3tq9A-2bzuA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.85A 4dfrB-2bzuA:
undetectable		 4dfrB-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.91A 4ej1A-2bzuA:
undetectable		 4ej1A-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.99A 4fhbA-2bzuA:
undetectable		 4fhbA-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 1.01A 4i13A-2bzuA:
undetectable		 4i13A-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.95A 4kjjA-2bzuA:
undetectable		 4kjjA-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.81A 4kjkA-2bzuA:
undetectable		 4kjkA-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		4 / 8 PHE A 374
TYR A 245
GLY A 271
ALA A 300
 None
 0.91A 4m48A-2bzuA:
undetectable		 4m48A-2bzuA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.78A 4p3rA-2bzuA:
undetectable		 4p3rA-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.77A 4pthA-2bzuA:
undetectable		 4pthA-2bzuA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		3 / 3 THR A 305
HIS A 375
LEU A 272
 None
 0.80A 5axdA-2bzuA:
undetectable		 5axdA-2bzuA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		3 / 3 THR A 305
HIS A 375
LEU A 272
 None
 0.79A 5axdC-2bzuA:
undetectable		 5axdC-2bzuA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 PHE A 374
LEU A 252
LEU A 286
PHE A 349
ALA A 379
 None
 1.26A 5ieoA-2bzuA:
undetectable		 5ieoA-2bzuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 LEU A 254
LEU A 256
LEU A 301
ALA A 318
MET A 322
 None
 0.91A 5og9B-2bzuA:
undetectable		 5og9B-2bzuA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.92A 5z6jA-2bzuA:
undetectable		 5z6jA-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		5 / 12 ILE A 267
LYS A 365
ILE A 244
LEU A 284
ILE A 269
 None
 0.97A 5z6kA-2bzuA:
undetectable		 5z6kA-2bzuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 2bzu FIBER PROTEIN 2
(Human
mastadenovirus
F) 		3 / 3 ILE A 347
THR A 348
PRO A 376
 None
 0.62A 6ncsA-2bzuA:
undetectable		 6ncsA-2bzuA:
19.93